PERAN KENDALI GLUKOSA TERHADAP KADAR VITAMIN D SERUM PADA PASIEN DIABETES MELITUS TIPE 2 DI MALANG

Background:Diabetes mellitus (DM) is a chronic metabolic disorder due to disruption insulin work, resulting in an increase of glucose concentration in the blood, or commonly called hyperglycemia. Hyperglycemia can also cause vitamin D serum interference because the micronutrients are involved in insulin signaling and action, also responsible in insulin sensitivity and secretion.This study will assess the effect of glucose control upon vitamin D serum levels of type 2 DM patients.Method:This research was analytic observational with cross sectional study using post-test only control group with research subjects (respondents) human male and female patients with diabetes mellitus without complications with an age range above 40 years. The research variables were classified into 2 groups, namely controlled group and uncontrolled group. Each control group of data respectively will depend on the vitamin D serum level using the Human 25-Dihydroxy Vitamin D (25-OH-D) ELISA kit. Data were analyzed using Independent T-Test followed by Pearson correlation test with a significance level of p<0.05.Result:Glucose control has no role in serum Vitamin D levels (p=0.754). This happened allegedly due to an error in the process of Vitamin D serum examination, and because of errors in the management of serum samples before use.Conclusion:Glucose control has no role in serum vitamin D levels towards patients with DM type 2.Keyword:glucose control, vitamin D serum, type 2 diabetes