145 research outputs found
CHARACTERISTICS OF A NEW OSCILLATING-PLATE VISCOMETER
Proceedings : 4th International Conference on Molten Slags and Fluxes (Molten Slags & Fluxes '92), 8-11 June, 1992, Sendai International Center, Sendai, Japa
Application of Thermodynamic Databases to the Evaluation of Surface Tensions of Molten Alloys, Salt Mixtures and Oxide Mixtures
Thermodynamic Relationship between the Enthalpy Interaction Parameter and Entropy Interaction Parameter in Liquid Iron-Nitrogen Based Ternary Alloys
Thermodynamic Relationship between Enthalpy of Mixing and Excess Entropy in Liquid Binary Alloys
Equilibrium Partition Coefficients between Solid and Liquid Phases and Activity Coefficients of Solute Elements in Ni Base Binary Dilute Alloys
Evaluation of Interaction Parameters in Dilute Liquid Ternary Alloys by a Solution Model Based on the Free Volume Theory
<Abstract of published report>Difference of Internal Structures of Underground Parts of Gentiana Lutea L. with Growth.
<Abstract of published report>Studies on Genus Urtica in Turkey (1) : Identification of Urtica in Turkey by Internal Structure of Axis and Petiole.
<Abstract of Published Report>Studies on Genus Urtica in Turkey (2). : Discrimination of Commercial Herb Drugs of Urtica in the Middle East.
Changing trends in prognostic factors for patients with multiple myeloma after autologous stem cell transplantation during the immunomodulator drug/proteasome inhibitor era
We evaluated the clinical significance of prognostic factors including the International Staging System (ISS) and modified European Group for Blood and Marrow Transplantation response criteria in 1650 Japanese patients with multiple myeloma (MM) who underwent upfront single autologous stem cell transplantation (ASCT). We categorized patients into two treatment cohorts: pre-novel agent era (1995-2006) and novel agent era (2008-2011). The combined percentage of pre-ASCT complete response and very good partial response cases (463 of 988, 47%) significantly increased during the novel agent era compared with the pre-novel agent era (164 of 527, 31%; P < 0.0001). The 2-year overall survival (OS) rate of 87% during the novel agent era was a significant improvement relative to that of 82% during the pre-novel agent era (P = 0.019). Although significant differences in OS were found among ISS stages during the pre-novel agent era, no significant difference was observed between ISS I and II (P = 0.107) during the novel agent era. The factors independently associated with a superior OS were female gender (P = 0.002), a good performance status (P = 0.024), lower ISS (P < 0.001), pre-ASCT response at least partial response (P < 0.001) and ASCT during the novel agent era (P = 0.017). These results indicate that the response rate and OS were significantly improved, and the ISS could not clearly stratify the prognoses of Japanese patients with MM who underwent upfront single ASCT during the novel agent era. © 2014 The Authors. Cancer Science published by Wiley Publishing Asia Pty Ltd on behalf of Japanese Cancer Association
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