Reflective Scattering and Unitarity

Interpretation of unitarity saturation as reflective scattering is discussed. Analogies with optics and Berry phase alongside with the experimental consequences of the proposed interpretation at the LHC energies are considered.Comment: 4 pages, 1 figure, talk given by S. Troshin at Diffraction 2008, September 9-14, La Londe-les-Maures, Franc

TMD PDF's: gauge invariance, RG properties and Wilson lines

The UV divergences associated with transverse-momentum dependent (TMD) parton distribution functions (PDF) are calculated together with the ensuing one-loop anomalous dimensions in the light-cone gauge. Time-reversal-odd effects in the anomalous dimensions are observed and the role of Glauber gluons is discussed. A generalized renormalization procedure of TMD PDFs is proposed, relying upon the renormalization of contour-dependent operators with obstructions.Comment: 4 pages, 1 figure. Talk presented at the International Workshop on Diffraction in High Energy and Nuclear Physics, La Londe-les-Maures, France, 9-14 Sept 2008. v2: 5 pages, preprint number and e-mail addresses adde

Prompt photon hadroproduction in the k_T-factorization approach

We study the production of prompt photons at high energy in the framework of the k_T-factorization approach. The amplitude for production of a single photon associated with quark pair in the fusion of two off-shell gluons is calculated. Theoretical results are compared with the Tevatron data.Comment: 4 pages, 3 figures, to be published in the Proceedings of Workshop "Diffraction 2008", La Londe-les-Maures, France, Sept. 9-14, 200

QCD and total cross-sections: photons and hadrons

In this contribution, we discuss a total cross-section model which can be applied to both photon and purely hadronic processes. We find that the model can reproduce photo-production cross-sections, as well as extrapolations of gamma* p processes to gamma p using vector meson dominance models, with minimal modifications from the proton case.Comment: 5 pages, 1 figure, to be published in Proceedings of Diffraction 2008, September 9-14 2008, Marseille, Franc

Displacement effect in strong-field atomic ionization by an XUV pulse

We study strong-field atomic ionization driven by an XUV pulse with a non\-zero displacement, the quantity defined as the integral of the pulse vector potential taken over the pulse duration. We demonstrate that the use of such pulses may lead to an extreme sensitivity of the ionization process to subtle changes of the parameters of a driving XUV pulse, in particular, the ramp-on/off profile and the carrier envelope phase. We illustrate this sensitivity for atomic hydrogen and lithium driven by few-femto\-second XUV pulses with intensity in the $\rm 10^{14}~W/cm^2$ range. We argue that the observed effect is general and should modify strong-field ionization of any atom, provided the ionization rate is sufficiently high.Comment: 5 pages, 7 figure

Molecular Cloning of a Bovine Immunoglobulin Lambda Chain cDNA

A cDNA library of the bovine mammary gland constructed in pBR322 was screened by mRNA hybrid-selected translation and by differential hybridization. Several immunoglobulin (Ig) λ light-chain clones were identified and sequenced. Nucleotide sequence comparison of bovine and human Ig λ chains showed a high degree of homology for constant regions and for J regions. The amino acid (aa) sequence encoded by the constant region of the bovine Ig λ chain cDNA contains 107 aa with differences at 24 aa positions from the human Ig A chain. Three complementarity-determining regions (CDR1,2,3) characteristic of the variable region of bovine Ig λ chain cDNA can be distinguished. The bovine and human sequences display good homology in the framework region 3 (FR3) but only patches of homology throughout the FR2 region. The 5′ end of the bovine Ig λ chain cDNA fragment of clone 1-14E contains five stop codons: two in CDR1, one in FR1 and two in the hydrophobic prepeptide region. These data suggest that the Igλ mRNA of clone 1-14E is transcribed from the Vλ pseudogene

N=1/2 gauge theory and its instanton moduli space from open strings in R-R background

We derive the four dimensional N=1/2 super Yang-Mills theory from tree-level computations in RNS open string theory with insertions of closed string Ramond-Ramond vertices. We also study instanton configurations in this gauge theory and their ADHM moduli space, using systems of D3 and D(-1) branes in a R-R background.Comment: 29 pages, 6 figures, JHEP class (included

Curare alkaloids from Matis Dart Poison: Comparison with d-tubocurarine in interactions with nicotinic, 5-HT3 serotonin and GABAA receptors.

Several novel bisbenzylisoquinoline alkaloids (BBIQAs) have recently been isolated from a Matis tribe arrow poison and shown by two-electrode voltage-clamp to inhibit mouse muscle nicotinic acetylcholine receptors (nAChR). Here, using radioligand assay with Aplysia californica AChBP and radioiodinated α-bungarotoxin ([125I]-αBgt), we show that BBIQA1, BBIQA2, and d-tubocurarine (d-TC) have similar affinities to nAChR orthosteric site. However, a competition with [125I]-αBgt for binding to the Torpedo californica muscle-type nAChR revealed that BBIQAs1, 2, and 3 are less potent (IC50s = 26.3, 8.75, and 17.0 μM) than d-TC (IC50 = 0.39 μM), while with α7 nAChR in GH4C1 cells, BBIQA1 was less potent that d-TC (IC50s = 162 μM and 7.77 μM, respectively), but BBIQA2 was similar (IC50 = 5.52 μM). In inhibiting the Ca2+ responses induced by acetylcholine in Neuro2a cells expressing the mouse adult α1β1εδ nAChR or human α7 nAChR, BBIQAs1 and 2 had similar potencies to d-TC (IC50s in the range 0.75-3.08 μM). Our data suggest that BBIQA1 and BBIQA2 can inhibit adult muscle α1β1εδ nAChR by both competitive and noncompetitive mechanisms. Further experiments on neuronal α3β2, α4β2, and α9α10 nAChRs, expressed in Xenopus laevis oocytes, showed that similar potencies for BBIQAs1, 2, and d-TC. With α3β2γ2 GABAAR currents were almost completely inhibited by d-TC at a high (100 μM) concentration, but BBIQAs1 and 2 were less potent (only 40-50% inhibition), whereas in competition with Alexa Fluor 546-α-cobratoxin for binding to α1β3γ2 GABAAR in Neuro2a cells, d-TC and these analogs had comparable affinities. Especially interesting effects of BBIQAs1 and 2 in comparison with d-TC were observed for 5-HT3AR: BBIQA1 and BBIQA2 were 5- and 87-fold less potent than d-TC (IC50 = 22.63 nM). Thus, our results reveal that these BBIQAs differ from d-TC in their potencies towards certain Cys-loop receptors, and we suggest that understanding the reasons behind this might be useful for future drug design.The work of ENS, IAI, DSK, IVS, AIG, LVS, and VIT was supported by the Russian Science Foundation Grant 16-14-00215 (http://rscf. ru/en). The work of IEK was supported by the Russian Foundation for Basic Research Grant 18- 04-01366 (http://www.rfbr.ru/rffi/eng). The work of SCRL was supported by a Medical Research Council Grant MR L021676 (https://mrc.ukri.org/)

Bi-harmonic superspace for N=4 d=4 super Yang-Mills

We develop N=4 d=4 bi-harmonic superspace and use it to derive a novel form for the low-energy effective action in N=4 super Yang-Mills theory. We solve the N=4 supergauge constraints in this superspace in terms of analytic superfields. Using these superfields, we construct a simple functional that respects N=4 supersymmetry and scale invariance. In components, it reproduces all on-shell terms in the four-derivative part of the N=4 SYM effective action; in particular, the F^4/X^4 and Wess-Zumino terms. The latter comes out in a novel SO(3) x SO(3)-invariant form.Comment: 1+19 pages; minor corrections, references adde