10 research outputs found

    Baseline characteristics of the external validation population and according to all-cause mortality and upper quartile of MR-proADM.

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    <p><sup>1</sup>GFR<60ml/min.</p><p><sup>2</sup>Long-term use of bronchodilatators or steroids.</p><p>Abbreviations: GFR = glomerular filtration rate, SAVR = surgical aortic valve replacement, CABG = coronary artery bypass grafting, MI = myocardial infarction, NYHA = New York Heart Association, COPD = chronic obstructive pulmonary disease, BMI = body mass index, CAD = coronary artery disease.</p><p>Baseline characteristics of the external validation population and according to all-cause mortality and upper quartile of MR-proADM.</p

    Baseline characteristics of the derivation study population according to all-cause mortality and upper quartile of MR-proADM.

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    <p><sup>1</sup>GFR<60ml/min.</p><p><sup>2</sup>Long-term use of bronchodilatators or steroids.</p><p>Abbreviations: GFR = glomerular filtration rate, SAVR = surgical aortic valve replacement, CABG = coronary artery bypass grafting, MI = myocardial infarction, NYHA = New York Heart Association, COPD = chronic obstructive pulmonary disease, BMI = body mass index, CAD = coronary artery disease.</p><p>Baseline characteristics of the derivation study population according to all-cause mortality and upper quartile of MR-proADM.</p

    Clinical model enhancement by addition of MR-proADM.

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    <p><b>Risk assessment plot for the reference (EuroSCORE II, dashed lines) and biomarker-enhanced (solid line) model for 1-year mortality;</b> 1-specificity versus calculated risk for those with the event and sensitivity versus calculated risk for those without events are shown.</p

    Validation of the RP-derived PI.

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    <p><b>Solid lines: Kaplan-Meier survival curves in two prognostic groups (upper and lower quartiles of predicted risk) in the validation cohort.</b> Dashed lines: RP mean survival functions in the same prognostic groups of the validation cohort by the model fit to the derivation cohort.</p
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