Additional file 1: of GWAS-identified CCR1 and IL10 loci contribute to M1 macrophage-predominant inflammation in Behçet’s disease

Figure S1. Comparison of phenotypic features and cytokine profiles between M1 and M2 cultured cells. Figure S2. eQTL effect of rs7616215 on CCR2 and CCR1. Figure S3. Detailed results of chemotaxis of M2 Mφ toward various concentrations of MIP-1α. Figure S4. Differences in CCR1 positivity (fluorescence-activated cell sorting) between treatments. a Biologics. b Colchicine. c Prednisolone. Figure S5. The number of differentiated Mφ in vitro in HC and BD. Figure S6. eQTL effect of rs1518111 on IL-10 protein and mRNA. Figure S7. Schema showing our proposed immunological responses in BD. Table S1. Characteristics of patients with BD who participated in the study. Table S2. Characteristics of HC study participants. (DOCX 9663 kb

Additional file 1: of Dysregulated heme oxygenase-1low M2-like macrophages augment lupus nephritis via Bach1 induced by type I interferons

Table S1. Primer sequences used for qRT-PCR. Figure S1. Numbers of CD68, CD163, HO-1 positive cells in the glomerulus of lupus nephritis patients (ClassI or II). Figure S2. Numbers of CD68, CD163, HO-1 positive cells in the extra-glomerulus of lupus nephritis patients. Figure S3. HO-1 mRNA expression in M1 and M2 Mϕ stimulated with various regents. Figure S4. Genomic background of congenic mice. Figure S5. Genotyping of Bach1 knockout mice. (DOCX 953 kb