Trichobezoar as Cause of Anorexia in A West African Dwarf Goat

Nigerian Veterinary Journal, VOL:32 (4) 362-36

Genetic variant of canine distemper virus from clinical cases in vaccinated dogs in South Africa

Canine distemper virus (CDV) is a highly contagious viral pathogen of worldwide distribution that can cause lethal disease in domestic dogs and other members of the family Canidae. Genetic diversity is found among reference strains and isolates of CDV, mainly in the haemagglutinin (H) protein, and this may be associated with the increasing incidence of distemper in dogs. CDV was isolated in Vero cells expressing canine signalling lymphocyte activation molecule (Vero.DogSLAM) from peripheralblood mononuclear cells and spleen of clinically diseased, previously vaccinated South African dogs. Direct fluorescence antibody test and electronmicroscopy were used to confirm the isolation procedure. Subsequently, RT-PCR was performed on the cell culture isolates, the amplified products were purified and the complete H gene wassequenced and phylogenetically analysed. The H gene of vaccines in use in South Africa was also sequenced and comparative analyses performed. However, the sequences obtained from the sick dogs showed 100% nucleotide identity and was different to that found in virus strains used in vaccines and in isolates reported from other parts of the world in GenBank. The results suggest that a novel CDV lineage may be present in South Africa and we conclude that a recent reversion of vaccine virus to virulence was not the cause of the clinical signs seen in dogs with a previoushistory of vaccination

Coccidioidomycosis in Chicken Pullets in Jos, Plateau State, Nigeria: A Case Report

No Abstract

Levels Of Haemoglobin And Packed Cell Volumes In Umbilical Cord Blood In Jos

Haemoglobin and packed cell volume have been studied in many neonatal study populations, but in Jos, Nigeria, no real reference values exist. On the other hand, disorders of the blood are common in this environment, necessitating knowledge of the references values of blood parameters as are applicable to neonates. Blood samples were taken from 121 umbilical cords at time of birth, and were analysed for haemoglobin concentration (Hb) and packed cell volume (PCV). The Hb concentration was determined by the indirect colorimetric method, and the PCV by the microhaematocrit centrifuge method. The mean values obtained were Hb 12.13 ± 0.11 g/dl and PCV 37.95 ± 0.49%. The mean umbilical cord blood haemoglobin and packed cell volumes were compared with those of the mothers, taken also at the time of delivery. The maternal values were Hb 10.87 ± 0.012 g/dl and PCV 34.51 ± 0.045%. The comparison shows statistically significant difference in Hb (

Abo And Rhesus Blood Groups Distribution In Mothers And Neonates In A Nigerian Population

Objective: To provide information in the distribution of ABO and Rhesus Blood Group in our population. Study Population/Methods: One hundred and twenty one antenatal mothers who were sequentially booked in antenatal care clinic of University of Jos Health Clinic, Jos, Plateau State after their informed consent. Cord blood was obtained from the babies of these mothers at birth. ABO and Rhesus blood groups were determined by Dacie and Lewis Methods. Result: Blood group O is the most common blood group representing 74% and 75% in mothers and their babies respectively. The distribution of group B is 13% in mothers and 12% in their babies. The distribution of A and AB groups among mothers and their babies is 10% and 3% respectively. There is a 100% Rhesus positivity in both mothers and neonates. Conclusion: The Rhesus negativity is very rare. There should still be need to test intending to marry couples before they start having children. Key words: Maternal, Umbilical Cord Blood, ABO & Rhesus blood groups. Highland Medical Research Journal Vol.1(1) 2002: 11-1

An Analysis Of QRS Interval Of The Electrocardiogram In Asymptomatic Normal Nigerians

Objectives: This cross-sectional study of the 12-lead electrocardiogram (ECG) was undertaken to establish the normal QRS interval of the adult Nigerian from Jos; to find significant correlation coefficients for QRS interval and the various anthropometric measurements and also to establish prediction equations for the QRS interval of the electrocardiogram. Methods: The QRS interval was measured in 109 young healthy adult Nigerians. Males numbered ninety-five and females numbered fourteen. They were aged between 19 years and 30 years. Results: The mean values for QRS interval in the 12-lead ECG were: Sec ± S.D (Lead 1:0.06 ± 0.01; lead II: 0.07 ± 0.01; lead III 0.07 ± 0.01; lead aVR: 0.07 ± 0.01; lead aVL: 0.07 ± 0.01; lead aVF: 0.08 ± 0.02; lead V1: 0.10 ± 0.04; lead V2:0.10 ± 0.01; lead V3: 0.08 ± 0.01; lead V4:0.07 ± 0.02; lead ± V5: 0.07 ± 0.01; lead V6: 0.07 ± 0.02). Significant inverse correlation was found between: (1) QRS interval and age in lead aVR. (2) QRS interval and weight in lead V3. (3) QRS interval and the systolic blood pressure in lead V1. (4) QRS interval and the diastolic blood pressure in leads aVR and V1. (5) QRS interval and the chest circumference in lead V3. Conclusion : This study has demonstrated the normal range (0.06 ± 0.01 sec in lead 1 to 0.10 ± 0.01 sec in level V2) for the QRS interval in young adult normal Nigerians in Jos and thus provided a precise guide for the interpretation of QRS interval in this city. Key words: QRS interval, Electrocardiogram, asymptomatic, Cross-sectional study. Highland Medical Research Journal Vol.2(2) 2004: 37-4

Renal Function in Pregnant and Non-Pregnant Women in Calabar, Nigeria

Pregnancy affects the physiology of the pregnant woman, particularly the cardiovascular, renal and endocrine systems. In this study 120 adult women were divided into four groups of two non-pregnant and two pregnant women consisting of 30 women each. The non-pregnant were the nulliparous (control of 30 women) and grand multiparous women who had stopped gestation (GMS) for at least 2 years (30 women). The sixty pregnant women were divided into primigravidal (PG) of 30 women and gradmultiparous (GMP) of 30 women also. Glomerular filtration rate (GFR) was measured in these women using endogenous creatinine clearance (Ccr). The pregnant women were studied during their 1st, 2nd and 3rd trimester. The results show that control, PG, GMP and GMS groups had a mean GFR of 99.20 + 2.16, 115 + 3.41, 113 + 3.08 and 114 + 3.20 respectively. The mean GFR increased significantly (

Studies on the S Wave of the Electrocardiogram: A Preliminary Report

We describe a preliminary cross-sectional study on the S wave of the 12-lead scalar electrocardiogram (ECG) in asymptomatic adult Nigerians. The study population consisted of a hundred and nine subjects aged nineteen to thirty years. They were all students of the University of Jos. The S wave amplitude (depth) and duration were measured and anlyzed in the 12-lead ECG in the study population. The range for mean S wave voltage was .14+ .05 to 1.21 + .53 mV. The ranges for mean S wave duration was 0.4 + .01 to .06 + .01 Sec. Significant correlation was found between S wave duration and amplitude and various anthropometric measurements. Prediction equations was derived for S wave voltage versus age, height, systolic blood pressure and S wave duration and age. The study has sought to measure the normal range for the S wave duration and amplitude in the 12-lead ECG. It has also documented some derived prediction equations. It is concluded that the results of this study can provide invaluable guidance about the interpretation of normal S wave of adult Nigerians in this metropolis. KEY WORDS: Cross-sectional study; electrocardiogram (ECG); S wave duration; S wave amplitude (voltage; depth); prediction equation; asymptomatic; healthy. Nigerian Journal of Health and Biomedical Sciences Vol.3(2) 2004: 85-8

Effect of an Aqueous Extract of Allium Sativum Linn on the Intestinal Motility of the Rabbit

The effect and probable mechanism of action of an aqueous extract of Allium sativum on intestinal motility of the rabbit was studied. Four rabbits were used as experimental animals in this study, and the standard organ bath procedure was used to monitor and record the contractions of the isolated intestine of the rabbits. The effects of acetylcholine, atropine and propranolol were also studied in the presence of the extract in the organ bath. The results show strong correlation between the log concentration of the extract and the percentage relaxation of the ileum, with r = 0.930325. This correlation was highly significant (

P Wave Ananysis In Asymptomatic Healthy Adult Nigerian Students: A Preliminary Study

The P wave amplitude and duration were measured and analyzed in the 12-lead ECG in a hundred and nine subjects aged between 19 and 30 years. The mean P wave duration was 0.07 ± 0.02 sec. Significant correlation was found between P wave duration and amplitude and various anthropometric measurements. Prediction equation was derived for the mean P wave voltage and the systolic blood pressure. The study has demonstrated the normal range for the P wave duration and amplitude. It thus provides a reference guide for the quantitative interpretations of the P waves of healthy adult Nigerians in Jos. Key words: Electrocardiogram (ECG), P wave duration, P. wave amplitude, prediction equation, asymptomatic. Nigerian Journal of Physiological Sciences Vol.18(1-2) 2003: 18-2