254 research outputs found

    Sustainable supply chain management in the digitalisation era: The impact of Automated Guided Vehicles

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    Internationalization of markets and climate change introduce multifaceted challenges for modern supply chain (SC) management in the today's digitalisation era. On the other hand, Automated Guided Vehicle (AGV) systems have reached an age of maturity that allows for their utilization towards tackling dynamic market conditions and aligning SC management focus with sustainability considerations. However, extant research only myopically tackles the sustainability potential of AGVs, focusing more on addressing network optimization problems and less on developing integrated and systematic methodological approaches for promoting economic, environmental and social sustainability. To that end, the present study provides a critical taxonomy of key decisions for facilitating the adoption of AGV systems into SC design and planning, as these are mapped on the relevant strategic, tactical and operational levels of the natural hierarchy. We then propose the Sustainable Supply Chain Cube (S2C2), a conceptual tool that integrates sustainable SC management with the proposed hierarchical decision-making framework for AGVs. Market opportunities and the potential of integrating AGVs into a SC context with the use of the S2C2 tool are further discussed

    Design of sustainable supply chains for the agrifood sector: a holistic research framework

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    Agrifood sector is one of the most important economic and political areas within the European Union, with key implications for sustainability such as the fulfillment of human needs, the support of employment and economic growth, and its impact on the natural environment.  Growing environmental, social and ethical concerns and increased awareness of the impacts of the agrifood sector have led to increased pressure by all involved supply chain stakeholders, while at the same time the European Union has undertaken a number of relevant regulatory interventions.  This paper aims to present a methodological framework for the design of green supply chains for the agrifood sector.  The framework aims towards the optimization of the agrifood supply chain design, planning and operations through the implementation of appropriate green supply chain management and logistics principles.  More specifically, focus is put on the minimization of the environmental burden and the maximization of supply chain sustainability of the agrifood supply chain.  The application of such a framework could result into substantial reduction of CO2 emissions both by the additional production of other biofuels from waste, as well as the introduction of a novel intelligent logistics network, in order to reduce the harvest and transportation energy input.  Moreover, the expansion of the biomass feedstock available for biofuel production can provide adequate support towards avoidance of food/fuel competition for land use.   Keywords: supply chain management, green supply chains, sustainable development, agrifood secto

    The impact of slow steaming on the carriers’ and shippers’ costs: The case of a global logistics network

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    We propose an analytical modeling methodology for quantifying the impact of slow steaming on the carrier's voyage cost and on the shipper's total landed logistics costs. The developed methodology can be employed by a carrier and a shipper in their contract negotiations, in order for the two parties to determine how they could divide between them the savings resulted from slow steaming. We demonstrate that the impact of slow steaming and speed adjustment policies on the shippers’ total landed logistics costs tend to increase as the vessel travels towards the end of its voyage

    An Integrated System Dynamics and Discrete Event Supply Chain Simulation Framework for Supply Chain Resilience with Non-Stationary Pandemic Demand

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    COVID-19 resulted in some of the largest supply chain disruptions in recent history. To mitigate the impact of future disruptions, we propose an integrated hybrid simulation framework to couple nonstationary demand signals from an event like COVID-19 with a model of an end-to-end supply chain. We first create a system dynamics susceptible-infected-recovered (SIR) model, augmenting a classic epidemiological model to create a realistic portrayal of demand patterns for oxygen concentrators (OC). Informed by this granular demand signal, we then create a supply chain discrete event simulation model of OC sourcing, manufacturing, and distribution to test production augmentation policies to satisfy this increased demand. This model utilizes publicly available data, engineering teardowns of OCs, and a supply chain illumination to identify suppliers. Our findings indicate that this coupled approach can use realistic demand during a disruptive event to enable rapid recommendations of policies for increased supply chain resilience with controlled cost

    Synchronous parathyroid adenoma and thyroid papillary carcinoma: a case report

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    A 51-year-old female patient presented with atypical chest pain, laryngo-oesophageal reflux, increased levels of serum calcium and parathyroid hormone. Ultrasonography showed a multinodular goiter with a prominent solid nodule in the lower left thyroid lobe and a solid hypoechoic nodule outside this area

    The impact of electronic versus paper-based data capture on data collection logistics and on missing scores in thyroid cancer patients.

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    The purpose of this study was to investigate the impact of the type of data capture on the time and help needed for collecting patient-reported outcomes as well as on the proportion of missing scores. In a multinational prospective study, thyroid cancer patients from 17 countries completed a validated questionnaire measuring quality of life. Electronic data capture was compared to the paper-based approach using multivariate logistic regression. A total of 437 patients were included, of whom 13% used electronic data capture. The relation between data capture and time needed was modified by the emotional functioning of the patients. Those with clinical impairments in that respect needed more time to complete the questionnaire when they used electronic data capture compared to paper and pencil (OR <sub>adj</sub> 24.0; p = 0.006). This was not the case when patients had sub-threshold emotional problems (OR <sub>adj</sub> 1.9; p = 0.48). The odds of having the researcher reading the questions out (instead of the patient doing this themselves) (OR <sub>adj</sub> 0.1; p = 0.01) and of needing any help (OR <sub>adj</sub> 0.1; p = 0.01) were lower when electronic data capture was used. The proportion of missing scores was equivalent in both groups (OR <sub>adj</sub> 0.4, p = 0.42). The advantages of electronic data capture, such as real-time assessment and fewer data entry errors, may come at the price of more time required for data collection when the patients have mental health problems. As this is not uncommon in thyroid cancer, researchers need to choose the type of data capture wisely for their particular research question

    Develop a cost model to evaluate the economic benefit of remanufacturing based on specific technique

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    Remanufacturing is a process of recovering used products to a like-new condition. It can potentially achieve considerable economic, environmental and social benefits in many applications. However, its economic benefit varies for different products and remanufacturing processes. This research aims to develop a framework and cost model to quantitatively evaluate the benefits of remanufacturing techniques to assist the decision making on end-of-life strategies. Additive manufacturing-based remanufacturing process has been modelled first, then cost breakdown structure for the process has been created, and the cost model has been developed. Validation of the cost model has been conducted based on expert judgement, and a case study has been carried out by using the developed cost model to compare the benefit of remanufacturing a specified component or making a new one

    Revascularization for Unprotected Left Main Coronary Artery Disease: An Evolution in Clinical Decision Making

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    Coronary artery bypass grafting (CABG) has been considered the standard therapy for unprotected (nonrevascularized) left main coronary disease (ULM). However, increasing experience with ULM percutaneous coronary intervention (PCI) has resulted in high procedural success and favorable early and late clinical outcomes. In particular, reduction in clinical restenosis with drug-eluting stents, evolution of procedural technique, and demonstration of favorable outcomes from comparative trials with CABG have promoted consideration of PCI as an alternative revascularization strategy in selected patients with ULM disease. This review summarizes the results from comparative studies examining PCI versus CABG for ULM disease, discusses changing indications for ULM PCI and identifies outstanding issues that must be considered before further advancing treatment recommendations
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