Cellulose acetate in wound dressings formulations: potentialities and electrospinning capability

Série: IFMBE Proceedings, vol. 76Any open wound is a potential site for microorganisms’ invasion since their presence around us is inevitable. Skin wound healing relies on a series of complex physiochemical processes that remain a big challenge for healthcare professionals, particularly when the wounds are colonized by bacteria. Wound dressings play a major role in wound healing as they manage the wounded site, controlling the moisture balance and protecting the wound from repeated trauma, and by preventing possible infections from developing into more serious complications. Recently, bioactive dressings loaded with drugs and/or antimicrobial agents, allowing for a continuous and sustainable release of these molecules at the wounded site, have appeared in the market. Antimicrobial resistance is a growing health care problem, requiring more effective solutions than antibiotics. As such, nano- and microfibrous mats produced via electrospinning technique and loaded with natural-origin antimicrobial agents have attracted a lot of attention. Various polymers have been applied to engineer nanofibrous electrospun dressings. However, the environment impact of the synthesis and processing methods of synthetic polymers is undesirable. Therefore, the application of cellulose-derived materials (highly abundant polymer of natural-origin) becomes crucial as a green alternative to produce electrospun wound dressings with superior wettability, breathability and high capacity to promote cell proliferation, at relatively low costs. In this paper, different biomolecules loaded onto cellulose acetate (CA)-based polymeric nanofibers were investigated, and their antimicrobial properties were highlighted as alternatives to conventional antibiotics.Authors acknowledge the Portuguese Foundation for Science and Technology (FCT), FEDER funds by means of Competitive Factors Operational Program (POCI) for funding the projects POCI-01-0145-FEDER-028074 and UID/CTM/00264/2019

The Algol System SZ Herculis: Physical Nature and Orbital Behavior

Multiband CCD photometric observations of SZ Her were obtained between 2008 February and May. The light curve was completely covered and indicated a significant temperature difference between both components. The light-curve synthesis presented in this paper indicates that the eclipsing binary is a classical Algol-type system with parameters of $q$=0.472, $i$=87$^\circ$.57, and $\Delta$($T_{1}$--$T_{2}$)=2,381 K; the primary component fills approximately 77% of its limiting lobe and is slightly larger than the lobe-filling secondary. More than 1,100 times of minimum light spanning more than one century were used to study an orbital behavior of the binary system. It was found that the orbital period of SZ Her has varied due to a combination of two periodic variations with cycle lengths of $P_3$=85.8 yr and $P_4$=42.5 yr and semi-amplitudes of $K_3$=0.013 d and $K_4$=0.007 d, respectively. The most reasonable explanation for them is a pair of light-time effects (LITEs) driven by the possible existence of two M-type companions with minimum masses of $M_3$=0.22 M$_\odot$ and $M_4$=0.19 M$_\odot$, that are located close to the 2:1 mean motion resonance. If two additional bodies exist, then the overall dynamics of the multiple system may provide a significant clue to the formation and evolution of the eclipsing pair.Comment: 23 pages, including 5 figures and 7 tables, accepted for publication in A

Site-Specific Based Models

This chapter reviews the major conceptual approaches and specifications for the design of Site-Specific Weed Management Decision Support Systems (SSWM-DSS), recent advances in the use of remote and ground platforms and sensors for information gathering and processing and initial experiences translating this information into chemical and physical weed control actuations through decision algorithms and modelsPeer reviewe

Site-Specific Based Models

This chapter reviews the major conceptual approaches and specifications for the design of site-specific weed management decision support systems (SSWM-DSS), recent advances in the use of remote and ground platforms and sensors for information gathering and processing, and initial experiences translating this information into chemical and physical weed control actuations through decision algorithms and models.Peer reviewe