7 research outputs found

    Π”Π»ΠΈΡ‚Π΅Π»ΡŒΠ½Π°Ρ тСрапия Π±ΠΎΠ»ΡŒΠ½Ρ‹Ρ… с тяТСлым Ρ‚Π΅Ρ‡Π΅Π½ΠΈΠ΅ΠΌ Π°ΠΊΠ½Π΅: Π²Ρ‹Π±ΠΎΡ€ Π΄ΠΎΠ· ΠΈ схСм ΠΏΡ€ΠΈΠ΅ΠΌΠ° систСмного ΠΈΠ·ΠΎΡ‚Ρ€Π΅Ρ‚ΠΈΠ½ΠΎΠΈΠ½Π°

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    The article presents current data on the application of a systemic retinoid, isotretinoin, on the basis of the Lidose system for the treatment of patients with severe forms of acne. It also discusses issues of optimization of the daily dose of isotretinoin taking into consideration long-term clinical efficacy and safety of the therapy. The article presents the results of the authors’ study demonstrating the possibility to select mainly large or small doses of systemic isotretinoin depending on the treatment duration.ΠŸΡ€ΠΈΠ²ΠΎΠ΄ΡΡ‚ΡΡ соврСмСнныС Π΄Π°Π½Π½Ρ‹Π΅ ΠΎ ΠΏΡ€ΠΈΠΌΠ΅Π½Π΅Π½ΠΈΠΈ систСмного Ρ€Π΅Ρ‚ΠΈΠ½ΠΎΠΈΠ΄Π° ΠΈΠ·ΠΎΡ‚Ρ€Π΅Ρ‚ΠΈΠ½ΠΎΠΈΠ½Π° Π½Π° основС систСмы Lidose Π² Π»Π΅Ρ‡Π΅Π½ΠΈΠΈ Π±ΠΎΠ»ΡŒΠ½Ρ‹Ρ… с тяТСлыми Ρ„ΠΎΡ€ΠΌΠ°ΠΌΠΈ Π°ΠΊΠ½Π΅. ΠžΠ±ΡΡƒΠΆΠ΄Π°ΡŽΡ‚ΡΡ вопросы ΠΎΠΏΡ‚ΠΈΠΌΠΈΠ·Π°Ρ†ΠΈΠΈ суточной Π΄ΠΎΠ·Ρ‹ ΠΈΠ·ΠΎΡ‚Ρ€Π΅Ρ‚ΠΈΠ½ΠΎΠΈΠ½Π° с ΡƒΡ‡Π΅Ρ‚ΠΎΠΌ долгосрочной клиничСской эффСктивности ΠΈ бСзопасности ΠΏΡ€ΠΎΠ²ΠΎΠ΄ΠΈΠΌΠΎΠΉ Ρ‚Π΅Ρ€Π°ΠΏΠΈΠΈ. ΠŸΡ€ΠΈΠ²ΠΎΠ΄ΡΡ‚ΡΡ Ρ€Π΅Π·ΡƒΠ»ΡŒΡ‚Π°Ρ‚Ρ‹ собствСнного исслСдования, Π΄Π΅ΠΌΠΎΠ½ΡΡ‚Ρ€ΠΈΡ€ΡƒΡŽΡ‰ΠΈΠ΅ Π²ΠΎΠ·ΠΌΠΎΠΆΠ½ΠΎΡΡ‚ΡŒ Π²Ρ‹Π±ΠΎΡ€Π° прСимущСствСнно Π±ΠΎΠ»ΡŒΡˆΠΈΡ…, Π»ΠΈΠ±ΠΎ ΠΌΠ°Π»Ρ‹Ρ… Π΄ΠΎΠ· систСмного ΠΈΠ·ΠΎΡ‚Ρ€Π΅Ρ‚ΠΈΠ½ΠΎΠΈΠ½Π° Π² зависимости ΠΎΡ‚ Π΄Π»ΠΈΡ‚Π΅Π»ΡŒΠ½ΠΎΡΡ‚ΠΈ прСдпринятого лСчСния

    Π­Ρ„Ρ„Π΅ΠΊΡ‚ΠΈΠ²Π½ΠΎΡΡ‚ΡŒ примСнСния узкополосной срСднСволновой ΡƒΠ»ΡŒΡ‚Ρ€Π°Ρ„ΠΈΠΎΠ»Π΅Ρ‚ΠΎΠ²ΠΎΠΉ Ρ‚Π΅Ρ€Π°ΠΏΠΈΠΈ 311 Π½ΠΌ ΠΏΡ€ΠΈ атопичСском Π΄Π΅Ρ€ΠΌΠ°Ρ‚ΠΈΡ‚Π΅ Ρƒ Π΄Π΅Ρ‚Π΅ΠΉ

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    The article presents the results of using a narrow-band mid-wavelength ultraviolet therapy (311 nm) in 79 children suffering from with atopic dermatitis. The course of treatment comprised 15 to 20 sessions of ultraviolet therapy with the maximal dose of irradiation being not more than 0.15 J/cm2. The control group (n=35) received traditional therapeutic treatment with the use of standard schemes of dosing and drug administration, and did not differ from the main group of patients in age, duration or form of the disease. Clinical efficacy of the therapy was estimated according to the SCORAD index, Dermatological Index of the Symptom Scale and Children's Dermatology Life Quality Index. The efficacy of the narrow-band mid-wavelength ultraviolet therapy (311 nm) turned out to be very high, which is confirmed by earlier reduction of clinical symptoms among patients from this group than in the control group. The latter fact was also confirmed by the reduction of absolute values of the SCORAD index and Dermatological Index of the Symptom Scale (pΠŸΡ€Π΅Π΄ΡΡ‚Π°Π²Π»Π΅Π½Ρ‹ Ρ€Π΅Π·ΡƒΠ»ΡŒΡ‚Π°Ρ‚Ρ‹ примСнСния Π² комплСксном Π»Π΅Ρ‡Π΅Π½ΠΈΠΈ 79 Π΄Π΅Ρ‚Π΅ΠΉ, Π±ΠΎΠ»ΡŒΠ½Ρ‹Ρ… атопичСским Π΄Π΅Ρ€ΠΌΠ°Ρ‚ΠΈΡ‚ΠΎΠΌ, узкополосной срСднСволновой Π£Π€Π’-Ρ‚Π΅Ρ€Π°ΠΏΠΈΠΈ (311 Π½ΠΌ). ΠšΡƒΡ€Ρ лСчСния состоял ΠΈΠ· 15-20 ΠΏΡ€ΠΎΡ†Π΅Π΄ΡƒΡ€ Π£Π€Π’-Ρ‚Π΅Ρ€Π°ΠΏΠΈΠΈ (311 Π½ΠΌ) с максимальной Ρ€Π°Π·ΠΎΠ²ΠΎΠΉ Π΄ΠΎΠ·ΠΎΠΉ облучСния Π½Π΅ Π±ΠΎΠ»Π΅Π΅ 0,15 Π”ΠΆ/см2. Π“Ρ€ΡƒΠΏΠΏΠ° сравнСния (35 Π±ΠΎΠ»ΡŒΠ½Ρ‹Ρ…) ΠΏΠΎΠ»ΡƒΡ‡Π°Π»Π° Ρ‚Ρ€Π°Π΄ΠΈΡ†ΠΈΠΎΠ½Π½ΡƒΡŽ Ρ‚Π΅Ρ€Π°ΠΏΠΈΡŽ с использованиСм стандартных Π΄ΠΎΠ· ΠΈ схСм ΠΏΡ€ΠΈΠ΅ΠΌΠ° лСкарствСнных ΠΏΡ€Π΅ΠΏΠ°Ρ€Π°Ρ‚ΠΎΠ² ΠΈ Π½Π΅ ΠΎΡ‚Π»ΠΈΡ‡Π°Π»Π°ΡΡŒ ΠΎΡ‚ основной Π³Ρ€ΡƒΠΏΠΏΡ‹ ΠΏΠΎ возрасту Π±ΠΎΠ»ΡŒΠ½Ρ‹Ρ…, Π΄Π»ΠΈΡ‚Π΅Π»ΡŒΠ½ΠΎΡΡ‚ΠΈ ΠΈ Ρ„ΠΎΡ€ΠΌΠ΅ заболСвания. ΠšΠ»ΠΈΠ½ΠΈΡ‡Π΅ΡΠΊΡƒΡŽ ΡΡ„Ρ„Π΅ΠΊΡ‚ΠΈΠ²Π½ΠΎΡΡ‚ΡŒ ΠΎΡ†Π΅Π½ΠΈΠ²Π°Π»ΠΈ ΠΏΠΎ Π΄ΠΈΠ½Π°ΠΌΠΈΠΊΠ΅ индСксов SCORAD, Π”Π˜Π¨Π‘ ΠΈ Π”Π”Π˜ΠšΠ–. УстановлСна высокая ΡΡ„Ρ„Π΅ΠΊΡ‚ΠΈΠ²Π½ΠΎΡΡ‚ΡŒ узкополосной срСднСволновой Π£Π€Π’-Ρ‚Π΅Ρ€Π°ΠΏΠΈΠΈ (311 Π½ΠΌ), ΠΎ Ρ‡Π΅ΠΌ ΡΠ²ΠΈΠ΄Π΅Ρ‚Π΅Π»ΡŒΡΡ‚Π²ΡƒΠ΅Ρ‚ Π±ΠΎΠ»Π΅Π΅ Ρ€Π°Π½Π½Π΅Π΅, Ρ‡Π΅ΠΌ Π² Π³Ρ€ΡƒΠΏΠΏΠ΅ сравнСния, ΡƒΠΌΠ΅Π½ΡŒΡˆΠ΅Π½ΠΈΠ΅ клиничСских симптомов, Ρ‡Ρ‚ΠΎ ΠΏΠΎΠ΄Ρ‚Π²Π΅Ρ€ΠΆΠ΄Π°Π»ΠΎΡΡŒ ΡƒΠΌΠ΅Π½ΡŒΡˆΠ΅Π½ΠΈΠ΅ΠΌ Π°Π±ΡΠΎΠ»ΡŽΡ‚Π½Ρ‹Ρ… Π²Π΅Π»ΠΈΡ‡ΠΈΠ½ индСксов SCORAD, Π”Π˜Π¨Π‘ (

    ΠœΠΈΠΊΡ€ΠΎΠ±Π½Π°Ρ экзСма: Π½ΠΎΠ²Ρ‹Π΅ возмоТностикомбинированной топичСской Ρ‚Π΅Ρ€Π°ΠΏΠΈΠΈ

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    The authors assessed clinical efficacy and safety of Supirocin-B for patients suffering from microbial eczema. The dynamic assessment of EASI, Dermatological Index of Symptom Scale, DLQI and results of bacterioscopic examination showed that evident positive results of the use of Supirocin-B in patients suffering from microbial eczema are related to the strong antibacterial action of such a topical antibiotic as Mupirocin as well as high topical anti-inflammatory action of betamethasone dipropionate.Π£ Π±ΠΎΠ»ΡŒΠ½Ρ‹Ρ… ΠΌΠΈΠΊΡ€ΠΎΠ±Π½ΠΎΠΉ экзСмой ΠΏΡ€ΠΎΠ²Π΅Π΄Π΅Π½Π° ΠΎΡ†Π΅Π½ΠΊΠ° клиничСской эффСктивности ΠΈ бСзопасности ΠΏΡ€Π΅ΠΏΠ°Ρ€Π°Ρ‚Π° Π‘ΡƒΠΏΠΈΡ€ΠΎΡ†ΠΈΠ½-Π‘. Π‘ ΠΏΠΎΠΌΠΎΡ‰ΡŒΡŽ динамичСской ΠΎΡ†Π΅Π½ΠΊΠΈ индСксов EASI, Π”Π˜Π¨Π‘, Π”Π˜ΠšΠ–, Π° Ρ‚Π°ΠΊΠΆΠ΅ бактСриоскопичСских исслСдований ΠΏΠΎΠΊΠ°Π·Π°Π½ΠΎ, Ρ‡Ρ‚ΠΎ ΠΎΡ‚Ρ‡Π΅Ρ‚Π»ΠΈΠ²Ρ‹Π΅ ΠΏΠΎΠ·ΠΈΡ‚ΠΈΠ²Π½Ρ‹Π΅ Ρ€Π΅Π·ΡƒΠ»ΡŒΡ‚Π°Ρ‚Ρ‹, ΠΏΠΎΠ»ΡƒΡ‡Π΅Π½Π½Ρ‹Π΅ ΠΏΡ€ΠΈ использовании ΠΌΠ°Π·ΠΈ Β«Π‘ΡƒΠΏΠΈΡ€ΠΎΡ†ΠΈΠ½-Π‘Β» Ρƒ Π±ΠΎΠ»ΡŒΠ½Ρ‹Ρ… ΠΌΠΈΠΊΡ€ΠΎΠ±Π½ΠΎΠΉ экзСмой, связаны с ΠΌΠΎΡ‰Π½Ρ‹ΠΌ Π°Π½Ρ‚ΠΈΠ±Π°ΠΊΡ‚Π΅Ρ€ΠΈΠ°Π»ΡŒΠ½Ρ‹ΠΌ дСйствиСм топичСского Π°Π½Ρ‚ΠΈΠ±ΠΈΠΎΡ‚ΠΈΠΊΠ° ΠΌΡƒΠΏΠΈΡ€ΠΎΡ†ΠΈΠ½Π°, Π° Ρ‚Π°ΠΊΠΆΠ΅ высокой мСстной ΠΏΡ€ΠΎΡ‚ΠΈΠ²ΠΎΠ²ΠΎΡΠΏΠ°Π»ΠΈΡ‚Π΅Π»ΡŒΠ½ΠΎΠΉ Π°ΠΊΡ‚ΠΈΠ²Π½ΠΎΡΡ‚ΡŒΡŽ Π±Π΅Ρ‚Π°ΠΌΠ΅Ρ‚Π°Π·ΠΎΠ½Π° Π΄ΠΈΠΏΡ€ΠΎΠΏΠΈΠΎΠ½Π°Ρ‚Π°

    The role of motivational factors which make interns choose specialty of dermatovenerologist

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    Objective: to analyze the main motivational and psychological factors influencing the success of the process of becoming a young medical interns in the specialty Β«DermatovenereologyΒ». Materials and methods. The study involved 49 interns in the specialty Β«DermatovenereologyΒ» (22 people studied in 2013-2014, 27 people β€” in 2014-2015). For the diagnosis it was used a Shortened multi-factor Personality inventory (RESINS), the technique of "career Anchors" diagnostic value orientations in karyes-re (E. Shane, translation and adaptation of V.A. Chiker, V. E. Vinokurov), Β«Survey of young specialists-sheetΒ» developed by GUZ Β«SACVDΒ» Results: A greater number of doctors interns of 2013 and 2014 and 2014-2015 chose the specialty Β«DermatovenerologyΒ» because of the possibility to work in the field of cosmetology. Conclusions. These results provide the possibility of selecting candidates for future employment, identify motivate innovative features, the ability of young professionals

    A clinical case of Stevens-Johnson syndrome in a patient with pustular psoriasis

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    Saratov Journal of Medical Scientific Research 2017; 13 (3): 646-648. The article presents a clinical case of Stevens β€” Johnson syndrome and generalized pustular patient with HIV-infection. The characteristic of anamnestic, clinical, laboratory data is present. The cause of acute allergic reactions and the formation of severe dermatosis in a patient with HIV-infection are considered.</p

    Topical therapy in patients with microbial eczema

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    &lt;p&gt;The study aimed to display that clinical and microbiologic research of patients with microbial eczema. The study revealed that the usage of co β€” formulated medication Supirocin β€” B was rather effcient, it promotes statistically authentic reduction of eczematous foci with pathogenic St.aureus and Str.spp. Besides, it has strong anti β€” infammatory effect and reduces eczematous process.&lt;/p&gt
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