FREQUENCY OF SIDE EFFECTS OF ANTIVIRUS THERAPY FOR CHRONIC VIRUS HEPATITIS IN CHILDHOOD

In pediatrics, the issue of using antivirus therapy for chronic virus hepatitis is not sufficiently studied, there is search for rational combinations, schemes, doses and length of treatment. The article demonstrates results of using a combined antivirus therapy with alpha interferon medications, interferon inducers, systemic enzymotherapy in children with chronic virus hepatitis B and C. Including systemic enzymotherapy medications in the combined treatment made it possible to reduce the number and severity of side effects of parenteral interferons. Key words: chronic hepatitis, antivirus therapy, alpha interferon, interferon inducers, children. (Pediatric Pharmacology. – 2010; 7(2):73-77

FREQUENCY OF SIDE EFFECTS OF ANTIVIRUS THERAPY FOR CHRONIC VIRUS HEPATITIS IN CHILDHOOD

In pediatrics, the issue of using antivirus therapy for chronic virus hepatitis is not sufficiently studied, there is search for rational combinations, schemes, doses and length of treatment. The article demonstrates results of using a combined antivirus therapy with alpha interferon medications, interferon inducers, systemic enzymotherapy in children with chronic virus hepatitis B and C. Including systemic enzymotherapy medications in the combined treatment made it possible to reduce the number and severity of side effects of parenteral interferons. Key words: chronic hepatitis, antivirus therapy, alpha interferon, interferon inducers, children. (Pediatric Pharmacology. – 2010; 7(2):73-77

PREVENTION OPPORTUNITIES FOR THE RESPIRATORY INFECTIONS AMONG CHILDREN WITH THE INSULIN DEPENDENT DIABETES

20 children with the insulin dependent diabetes have been vaccinated with pneumo 23 against pneumococcal infection during the two week prevention course by immunomodulating spray IRS 19. Topical lysate was prescribed on the day of vaccination in the season, immediately preceding the flu epidemy. Before application of topical lysate, as well as in a month and in 3 months after the pre vention course was over, the researchers evaluated the biocenose indices of nasal and fauces cavity mucosa. Alongside, otorhinolaryngologist examined the children. IRS 19 prescription helped to avoid the emergence of intercurrent diseases during the post vaccinal period, in the meantime, it led to the reduction of pathogenic flora sowing, intensity of the inflammatory changes in the nasal pharynx and fauces. Vaccination against pneumococcal infection and combined application of Pneumo 23 with IRS 19 among children with the insulin-dependent diabetes contributed to the reduction of frequency and severity of the respiratory ingections if compared with the similar indices of 43 patients with diabetes, who did not receive immunization.Key words: children, insulin dependent diabetes, chronic tonsillitis, tissue immunity, immunoregulatory spray, vaccine against pneumococcal infection

ЧАСТОТА ПОБОЧНЫХ ЭФФЕКТОВ ПРОТИВОВИРУСНОЙ ТЕРАПИИ ХРОНИЧЕСКИХ ВИРУСНЫХ ГЕПАТИТОВ В ДЕТСКОМ ВОЗРАСТЕ

In pediatrics, the issue of using antivirus therapy for chronic virus hepatitis is not sufficiently studied, there is search for rational combinations, schemes, doses and length of treatment. The article demonstrates results of using a combined antivirus therapy with alpha interferon medications, interferon inducers, systemic enzymotherapy in children with chronic virus hepatitis B and C. Including systemic enzymotherapy medications in the combined treatment made it possible to reduce the number and severity of side effects of parenteral interferons. Key words: chronic hepatitis, antivirus therapy, alpha interferon, interferon inducers, children. (Pediatric Pharmacology. – 2010; 7(2):73-77)В педиатрии вопрос применения противовирусной терапии при хронических вирусных гепатитах не достаточно изучен, продолжаются поиски рациональных комбинаций, схем, доз и длительности лечения. В статье представлены результаты применения комбинированной противовирусной терапии с использованием препаратов альфа-интерферона, индукторов интерферона, препаратов системной энзимотерапии у детей с хроническими вирусными гепатитами В и С. Ключевые слова: хронический гепатит, противовирусная терапия, интерферон ?, индукторы интерферона, дети. (Педиатрическая фармакология. – 2010; 7(2):73-77