1,253 research outputs found
Topological Gauge Structure and Phase Diagram for Weakly Doped Antiferromagnets
We show that the topological gauge structure in the phase string theory of
the {\rm t-J} model gives rise to a global phase diagram of antiferromagnetic
(AF) and superconducting (SC) phases in a weakly doped regime. Dual confinement
and deconfinement of holons and spinons play essential roles here, with a
quantum critical point at a doping concentration . The complex
experimental phase diagram at low doping is well described within such a
framework.Comment: 4 pages, 2 figures, modified version, to appear in Phys. Rev. Let
The colonic macrophage transcription factor RBP-J orchestrates intestinal immunity against bacterial pathogens
Macrophages play pleiotropic roles in maintaining the balance between immune tolerance and inflammatory responses in the gut. Here, we identified transcription factor RBP-J as a crucial regulator of colonic macrophage-mediated immune responses against the enteric pathogen Citrobacter rodentium. In the immune response phase, RBP-J promoted pathogen clearance by enhancing intestinal macrophage-elicited Th17 cell immune responses, which was achieved by maintenance of C/EBPβ-dependent IL-6 production by overcoming miRNA-17∼92-mediated suppressive effects. RBP-J deficiency-associated phenotypes could be genetically corrected by further deleting miRNA-17∼92 in macrophages. In the late phase, noneradicated pathogens in RBP-J KO mice recruited abundant IL-1β-expressing CD64+Ly6C+ colonic macrophages and thereby promoted persistence of ILC3-derived IL-22 to compensate for the impaired innate and adaptive immune responses, leading to ultimate clearance of pathogens. These results demonstrated that colonic macrophage-intrinsic RBP-J dynamically orchestrates intestinal immunity against pathogen infections by interfacing with key immune cells of T and innate lymphoid cell lineages
New Family of Robust 2D Topological Insulators in van der Waals Heterostructures
We predict a new family of robust two-dimensional (2D) topological insulators
in van der Waals heterostructures comprising graphene and chalcogenides BiTeX
(X=Cl, Br and I). The layered structures of both constituent materials produce
a naturally smooth interface that is conducive to proximity induced new
topological states. First principles calculations reveal intrinsic
topologically nontrivial bulk energy gaps as large as 70-80 meV, which can be
further enhanced up to 120 meV by compression. The strong spin-orbit coupling
in BiTeX has a significant influence on the graphene Dirac states, resulting in
the topologically nontrivial band structure, which is confirmed by calculated
nontrivial Z2 index and an explicit demonstration of metallic edge states. Such
heterostructures offer an unique Dirac transport system that combines the 2D
Dirac states from graphene and 1D Dirac edge states from the topological
insulator, and it offers new ideas for innovative device designs
Microstructural characterization of AISI 431 martensitic stainless steel laser-deposited coatings
High cooling rates during laser cladding of stainless steels may alter the microstructure and phase constitution of the claddings and consequently change their functional properties. In this research, solidification structures and solid state phase transformation products in single and multi layer AISI 431 martensitic stainless steel coatings deposited by laser cladding at different processing speeds are investigated by optical microscopy, Scanning electron microscopy (SEM), energy dispersive spectroscopy (EDS), orientation imaging microscopy (OIM), ternary phase diagram, Schaeffler and TTT diagrams. The results of this study show how partitionless solidification and higher solidification rates alter the microstructure and phase constitution of martensitic stainless steel laser deposited coatings. In addition, it is shown that while different cladding speeds have no effect on austenite–martensite orientation relationship in the coatings, increasing the cladding speed has resulted in a reduction of hardness in deposited coatings which is in contrast to the common idea about obtaining higher hardness values at higher cladding speeds.
- …