5 research outputs found
ΠΠ°ΡΠ°Π²Π΅ΡΡΠ΅Π±ΡΠ°Π»ΡΠ½Π°Ρ Π±Π»ΠΎΠΊΠ°Π΄Π° ΠΏΡΠΈ Π»Π΅ΡΠ΅Π½ΠΈΠΈ ΠΏΠ°ΡΠΈΠ΅Π½ΡΠΎΠ² Ρ Π·Π°ΠΊΡΡΡΠΎΠΉ ΡΡΠ°Π²ΠΌΠΎΠΉ Π³ΡΡΠ΄ΠΈ
The study was conducted in the Thoracoabdominal Department of the N.V. Sklifosovsky Research Institute for Emergency Medicine to explore the role of paravertebral block in the treatment of blunt chest trauma. The study included 715 patients with isolated chest trauma hospitalized between January 1, 2020 and August 2021. 55 patients received analgesic therapy in the form of paravertebral block. The comparison group included 660 patients who did not undergo paravertebral block, in their case pain relief was provided by systemic administration of analgesics. The compared groups did not differ significantly in sex and age composition. There were also no differences in the frequency of chronic diseases and interpleural complications. There were no significant complications during the block. The comparison revealed a significant decrease in the incidence of pleurisy and a shorter length of stay in hospital. Paravertebral block is an effective and safe method of pain management for patients with blunt chest trauma. The use of this technique reduces the incidence of post-traumatic pleurisy and duration of hospitalization.ΠΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΠ΅ ΠΏΡΠΎΠ²Π΅Π΄Π΅Π½ΠΎ Π² ΡΠΎΡΠ°ΠΊΠΎΠ°Π±Π΄ΠΎΠΌΠΈΠ½Π°Π»ΡΠ½ΠΎΠΌ ΠΎΡΠ΄Π΅Π»Π΅Π½ΠΈΠΈ ΠΠΠ Π‘Π ΠΈΠΌ. Π.Π. Π‘ΠΊΠ»ΠΈΡΠΎΡΠΎΠ²ΡΠΊΠΎΠ³ΠΎ Ρ ΡΠ΅Π»ΡΡ ΠΈΠ·ΡΡΠ΅Π½ΠΈΡ Π·Π½Π°ΡΠ΅Π½ΠΈΡ ΠΏΠ°ΡΠ°Π²Π΅ΡΡΠ΅Π±ΡΠ°Π»ΡΠ½ΠΎΠΉ Π±Π»ΠΎΠΊΠ°Π΄Ρ. ΠΡΠ»ΠΎ Π²ΠΊΠ»ΡΡΠ΅Π½ΠΎ 715 ΠΏΠ°ΡΠΈΠ΅Π½ΡΠΎΠ² Ρ ΠΈΠ·ΠΎΠ»ΠΈΡΠΎΠ²Π°Π½Π½ΠΎΠΉ ΡΡΠ°Π²ΠΌΠΎΠΉ Π³ΡΡΠ΄ΠΈ, Π³ΠΎΡΠΏΠΈΡΠ°Π»ΠΈΠ·ΠΈΡΠΎΠ²Π°Π½Π½ΡΡ
Π² ΡΠΊΡΡΡΠ΅Π½Π½ΠΎΠΌ ΠΏΠΎΡΡΠ΄ΠΊΠ΅ Π² ΠΏΠ΅ΡΠΈΠΎΠ΄ Ρ 1 ΡΠ½Π²Π°ΡΡ 2020 ΠΏΠΎ Π°Π²Π³ΡΡΡ 2021 Π³ΠΎΠ΄Π°; 55 ΠΏΠ°ΡΠΈΠ΅Π½ΡΠΎΠ² Π² Ρ
ΠΎΠ΄Π΅ Π»Π΅ΡΠ΅Π½ΠΈΡ ΠΏΠΎΠ»ΡΡΠΈΠ»ΠΈ ΠΎΠ±Π΅Π·Π±ΠΎΠ»ΠΈΠ²Π°ΡΡΡΡ ΡΠ΅ΡΠ°ΠΏΠΈΡ Π² Π²ΠΈΠ΄Π΅ ΠΏΠ°ΡΠ°Π²Π΅ΡΡΠ΅Π±ΡΠ°Π»ΡΠ½ΠΎΠΉ Π±Π»ΠΎΠΊΠ°Π΄Ρ. Π Π³ΡΡΠΏΠΏΡ ΡΡΠ°Π²Π½Π΅Π½ΠΈΡ Π²ΠΊΠ»ΡΡΠΈΠ»ΠΈ 660 ΠΏΠ°ΡΠΈΠ΅Π½ΡΠΎΠ², ΠΊΠΎΡΠΎΡΡΠΌ Π½Π΅ Π²ΡΠΏΠΎΠ»Π½ΡΠ»ΠΈ ΠΏΡΠΎΠ²ΠΎΠ΄Π½ΠΈΠΊΠΎΠ²ΡΡ Π±Π»ΠΎΠΊΠ°Π΄Ρ, ΠΎΠ±Π΅Π·Π±ΠΎΠ»ΠΈΠ²Π°Π½ΠΈΠ΅ ΠΎΠ±Π΅ΡΠΏΠ΅ΡΠΈΠ²Π°Π»ΠΈ ΡΠΈΡΡΠ΅ΠΌΠ½ΡΠΌ Π²Π²Π΅Π΄Π΅Π½ΠΈΠ΅ΠΌ Π°Π½Π°Π»ΡΠ³Π΅ΡΠΈΠΊΠΎΠ². Π‘ΡΠ°Π²Π½ΠΈΠ²Π°Π΅ΠΌΡΠ΅ Π³ΡΡΠΏΠΏΡ Π·Π½Π°ΡΠΈΠΌΠΎ Π½Π΅ ΠΎΡΠ»ΠΈΡΠ°Π»ΠΈΡΡ ΠΏΠΎ ΠΏΠΎΠ»ΠΎΠ²ΠΎΠΌΡ ΠΈ Π²ΠΎΠ·ΡΠ°ΡΡΠ½ΠΎΠΌΡ ΡΠΎΡΡΠ°Π²Ρ. ΠΡΠ»ΠΈΡΠΈΠΉ Π² ΡΠ°ΡΡΠΎΡΠ΅ Ρ
ΡΠΎΠ½ΠΈΡΠ΅ΡΠΊΠΈΡ
Π·Π°Π±ΠΎΠ»Π΅Π²Π°Π½ΠΈΠΉ ΠΈ ΠΈΠ½ΡΡΠ°ΠΏΠ»Π΅Π²ΡΠ°Π»ΡΠ½ΡΡ
ΠΎΡΠ»ΠΎΠΆΠ½Π΅Π½ΠΈΠΉ ΡΠ°ΠΊΠΆΠ΅ Π½Π΅ Π±ΡΠ»ΠΎ. ΠΠ½Π°ΡΠΈΠΌΡΡ
ΠΎΡΠ»ΠΎΠΆΠ½Π΅Π½ΠΈΠΉ ΠΏΡΠΈ Π²ΡΠΏΠΎΠ»Π½Π΅Π½ΠΈΠΈ Π±Π»ΠΎΠΊΠ°Π΄Ρ Π½Π΅ ΠΎΡΠΌΠ΅ΡΠ°Π»ΠΎΡΡ. ΠΡΠΈ ΡΡΠ°Π²Π½Π΅Π½ΠΈΠΈ Π²ΡΡΠ²Π»Π΅Π½ΠΎ Π΄ΠΎΡΡΠΎΠ²Π΅ΡΠ½ΠΎΠ΅ ΡΠΌΠ΅Π½ΡΡΠ΅Π½ΠΈΠ΅ ΡΠ°ΡΡΠΎΡΡ ΠΏΠ»Π΅Π²ΡΠΈΡΠ° ΠΈ Π±ΠΎΠ»Π΅Π΅ ΠΊΠΎΡΠΎΡΠΊΠΎΠ΅ Π²ΡΠ΅ΠΌΡ Π½Π°Ρ
ΠΎΠΆΠ΄Π΅Π½ΠΈΡ Π² ΡΡΠ°ΡΠΈΠΎΠ½Π°ΡΠ΅. ΠΠ°ΡΠ°Π²Π΅ΡΡΠ΅Π±ΡΠ°Π»ΡΠ½Π°Ρ Π±Π»ΠΎΠΊΠ°Π΄Π° ΡΠ²Π»ΡΠ΅ΡΡΡ ΡΡΡΠ΅ΠΊΡΠΈΠ²Π½ΡΠΌ ΠΈ Π±Π΅Π·ΠΎΠΏΠ°ΡΠ½ΡΠΌ ΠΌΠ΅ΡΠΎΠ΄ΠΎΠΌ ΠΎΠ±Π΅Π·Π±ΠΎΠ»ΠΈΠ²Π°Π½ΠΈΡ ΠΏΠ°ΡΠΈΠ΅Π½ΡΠΎΠ² Ρ Π·Π°ΠΊΡΡΡΠΎΠΉ ΡΡΠ°Π²ΠΌΠΎΠΉ Π³ΡΡΠ΄ΠΈ. ΠΡΠΏΠΎΠ»ΡΠ·ΠΎΠ²Π°Π½ΠΈΠ΅ ΡΡΠΎΠΉ ΠΌΠ΅ΡΠΎΠ΄ΠΈΠΊΠΈ ΡΠ½ΠΈΠΆΠ°Π΅Ρ ΡΠ°ΡΡΠΎΡΡ ΡΠ°Π·Π²ΠΈΡΠΈΡ ΠΏΠΎΡΡΡΡΠ°Π²ΠΌΠ°ΡΠΈΡΠ΅ΡΠΊΠΎΠ³ΠΎ ΠΏΠ»Π΅Π²ΡΠΈΡΠ° ΠΈ ΡΡΠΊΠΎΡΡΠ΅Ρ Π²ΡΠΏΠΈΡΠΊΡ Π±ΠΎΠ»ΡΠ½ΡΡ
ΠΠΎΠΌΠΏΡΡΡΠ΅ΡΠ½Π°Ρ ΡΠΎΠΌΠΎΠ³ΡΠ°ΡΠΈΡ ΠΏΡΠΈ ΡΠΏΠΎΠ½ΡΠ°Π½Π½ΠΎΠΉ Π³Π΅ΠΌΠ°ΡΠΎΠΌΠ΅ ΠΏΠΈΡΠ΅Π²ΠΎΠ΄Π°: Π½Π°Π΄Π΅ΠΆΠ½ΠΎΠ΅ ΡΠΎΠΏΡΠΎΠ²ΠΎΠΆΠ΄Π΅Π½ΠΈΠ΅ ΠΎΡ Π΄ΠΈΠ°Π³Π½ΠΎΡΡΠΈΠΊΠΈ Π΄ΠΎ Π²ΡΠ·Π΄ΠΎΡΠΎΠ²Π»Π΅Π½ΠΈΡ
The purpose of the study. To study the possibilities of computed tomography (CT) in the diagnosis of spontaneous hematoma of the esophagus, including in the process of dynamic observation.Materials and methods. A retrospective analysis of CT results in 11 patients with spontaneous esophageal hematoma treated at the N.V. Sklifosovsky Research Institute of SP in the period 2005β2020 is presented. All patients underwent a comprehensive laboratory and instrumental examination, including CT. CT studies were performed with oral and intravenous bolus contrast, primarily at admission and in dynamics.Results. In all cases, according to CT data, acute pathology of the aorta, rupture of the esophagus were excluded and signs of spontaneous hematoma of the esophagus were revealed. CT semiotics of esophageal hematoma was analyzed with quantitative treatment of changes in density, linear dimensions and volume. CT semiotics analysis also revealed the volumetric effect of hematoma on surrounding organs and structures, accumulation of blood in the pleural cavities, and verified signs of infection of hematoma with inflammatory changes in the surrounding paraesophageal tissue. CT data served as the basis for determining the optimal treatment tactics for spontaneous esophageal hematoma. Conservative therapy was the main method of her treatment. CT examination in dynamics allowed timely detection of complications of spontaneous hematoma of the esophagus (hemothorax, perforation of the esophagus, infection of the hematoma) requiring surgical intervention.Conclusion. CT is the method of choice in the diagnosis of spontaneous hematoma of the esophagus, which allows for a clear differential diagnosis with urgent life-threatening conditions. CT data make it possible to justify treatment tactics and assess the dynamics of the pathological process.Π¦Π΅Π»Ρ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΡ: ΠΈΠ·ΡΡΠΈΡΡ Π²ΠΎΠ·ΠΌΠΎΠΆΠ½ΠΎΡΡΠΈ ΠΊΠΎΠΌΠΏΡΡΡΠ΅ΡΠ½ΠΎΠΉ ΡΠΎΠΌΠΎΠ³ΡΠ°ΡΠΈΠΈ (ΠΠ’) Π² Π΄ΠΈΠ°Π³Π½ΠΎΡΡΠΈΠΊΠ΅ ΡΠΏΠΎΠ½ΡΠ°Π½Π½ΠΎΠΉ Π³Π΅ΠΌΠ°ΡΠΎΠΌΡ ΠΏΠΈΡΠ΅Π²ΠΎΠ΄Π°, Π² ΡΠΎΠΌ ΡΠΈΡΠ»Π΅ Π² ΠΏΡΠΎΡΠ΅ΡΡΠ΅ Π΄ΠΈΠ½Π°ΠΌΠΈΡΠ΅ΡΠΊΠΎΠ³ΠΎ Π½Π°Π±Π»ΡΠ΄Π΅Π½ΠΈΡ.ΠΠ°ΡΠ΅ΡΠΈΠ°Π» ΠΈ ΠΌΠ΅ΡΠΎΠ΄Ρ. ΠΡΠ΅Π΄ΡΡΠ°Π²Π»Π΅Π½ ΡΠ΅ΡΡΠΎΡΠΏΠ΅ΠΊΡΠΈΠ²Π½ΡΠΉ Π°Π½Π°Π»ΠΈΠ· ΡΠ΅Π·ΡΠ»ΡΡΠ°ΡΠΎΠ² ΠΠ’ Ρ 11 ΠΏΠ°ΡΠΈΠ΅Π½ΡΠΎΠ² ΡΠΎ ΡΠΏΠΎΠ½ΡΠ°Π½Π½ΠΎΠΉ Π³Π΅ΠΌΠ°ΡΠΎΠΌΠΎΠΉ ΠΏΠΈΡΠ΅Π²ΠΎΠ΄Π°, Π½Π°Ρ
ΠΎΠ΄ΠΈΠ²ΡΠΈΡ
ΡΡ Π½Π° Π»Π΅ΡΠ΅Π½ΠΈΠΈ Π² ΠΠΠ Π‘Π ΠΈΠΌ. Π.Π. Π‘ΠΊΠ»ΠΈΡΠΎΡΠΎΠ²ΡΠΊΠΎΠ³ΠΎ Π² ΠΏΠ΅ΡΠΈΠΎΠ΄ 2005β2020 Π³Π³. ΠΡΠ΅ΠΌ ΠΏΠ°ΡΠΈΠ΅Π½ΡΠ°ΠΌ Π±ΡΠ»ΠΎ Π²ΡΠΏΠΎΠ»Π½Π΅Π½ΠΎ ΠΊΠΎΠΌΠΏΠ»Π΅ΠΊΡΠ½ΠΎΠ΅ Π»Π°Π±ΠΎΡΠ°ΡΠΎΡΠ½ΠΎ-ΠΈΠ½ΡΡΡΡΠΌΠ΅Π½ΡΠ°Π»ΡΠ½ΠΎΠ΅ ΠΎΠ±ΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΠ΅, Π²ΠΊΠ»ΡΡΠ°Π²ΡΠ΅Π΅ ΠΠ’ Ρ ΠΏΠ΅ΡΠΎΡΠ°Π»ΡΠ½ΡΠΌ ΠΈ Π²Π½ΡΡΡΠΈΠ²Π΅Π½Π½ΡΠΌ Π±ΠΎΠ»ΡΡΠ½ΡΠΌ ΠΊΠΎΠ½ΡΡΠ°ΡΡΠΈΡΠΎΠ²Π°Π½ΠΈΠ΅ΠΌ, ΠΊΠ°ΠΊ ΠΏΠ΅ΡΠ²ΠΈΡΠ½ΠΎ ΠΏΡΠΈ ΠΏΠΎΡΡΡΠΏΠ»Π΅Π½ΠΈΠΈ, ΡΠ°ΠΊ ΠΈ Π² Π΄ΠΈΠ½Π°ΠΌΠΈΠΊΠ΅.Π Π΅Π·ΡΠ»ΡΡΠ°ΡΡ. ΠΠΎ Π²ΡΠ΅Ρ
ΡΠ»ΡΡΠ°ΡΡ
ΠΏΠΎ Π΄Π°Π½Π½ΡΠΌ ΠΠ’ Π±ΡΠ»ΠΈ ΠΈΡΠΊΠ»ΡΡΠ΅Π½Ρ ΠΎΡΡΡΠ°Ρ ΠΏΠ°ΡΠΎΠ»ΠΎΠ³ΠΈΡ Π°ΠΎΡΡΡ, ΡΠ°Π·ΡΡΠ² ΠΏΠΈΡΠ΅Π²ΠΎΠ΄Π° ΠΈ Π²ΡΡΠ²Π»Π΅Π½Ρ ΠΏΡΠΈΠ·Π½Π°ΠΊΠΈ ΡΠΏΠΎΠ½ΡΠ°Π½Π½ΠΎΠΉ Π³Π΅ΠΌΠ°ΡΠΎΠΌΡ ΠΏΠΈΡΠ΅Π²ΠΎΠ΄Π°. ΠΡΠΎΠ°Π½Π°Π»ΠΈΠ·ΠΈΡΠΎΠ²Π°Π½Π° ΠΠ’-ΡΠ΅ΠΌΠΈΠΎΡΠΈΠΊΠ° Π³Π΅ΠΌΠ°ΡΠΎΠΌΡ ΠΏΠΈΡΠ΅Π²ΠΎΠ΄Π° Ρ ΠΊΠΎΠ»ΠΈΡΠ΅ΡΡΠ²Π΅Π½Π½ΠΎΠΉ ΠΎΠ±ΡΠ°Π±ΠΎΡΠΊΠΎΠΉ ΠΈΠ·ΠΌΠ΅Π½Π΅Π½ΠΈΠΉ ΠΏΠΎ ΠΏΠ»ΠΎΡΠ½ΠΎΡΡΠΈ, Π»ΠΈΠ½Π΅ΠΉΠ½ΡΠΌ ΡΠ°Π·ΠΌΠ΅ΡΠ°ΠΌ ΠΈ ΠΎΠ±ΡΠ΅ΠΌΡ. ΠΠ½Π°Π»ΠΈΠ· ΠΠ’-ΡΠ΅ΠΌΠΈΠΎΡΠΈΠΊΠΈ ΡΠ°ΠΊΠΆΠ΅ ΠΏΠΎΠ·Π²ΠΎΠ»ΠΈΠ» Π²ΡΡΠ²ΠΈΡΡ ΠΎΠ±ΡΠ΅ΠΌΠ½ΠΎΠ΅ Π²ΠΎΠ·Π΄Π΅ΠΉΡΡΠ²ΠΈΠ΅ Π³Π΅ΠΌΠ°ΡΠΎΠΌΡ Π½Π° ΠΎΠΊΡΡΠΆΠ°ΡΡΠΈΠ΅ ΠΎΡΠ³Π°Π½Ρ ΠΈ ΡΡΡΡΠΊΡΡΡΡ, ΡΠΊΠΎΠΏΠ»Π΅Π½ΠΈΠ΅ ΠΊΡΠΎΠ²ΠΈ Π² ΠΏΠ»Π΅Π²ΡΠ°Π»ΡΠ½ΡΡ
ΠΏΠΎΠ»ΠΎΡΡΡΡ
, Π²Π΅ΡΠΈΡΠΈΡΠΈΡΠΎΠ²Π°ΡΡ ΠΏΡΠΈΠ·Π½Π°ΠΊΠΈ ΠΈΠ½ΡΠΈΡΠΈΡΠΎΠ²Π°Π½ΠΈΡ Π³Π΅ΠΌΠ°ΡΠΎΠΌΡ Ρ Π²ΠΎΡΠΏΠ°Π»ΠΈΡΠ΅Π»ΡΠ½ΡΠΌΠΈ ΠΈΠ·ΠΌΠ΅Π½Π΅Π½ΠΈΡΠΌΠΈ ΠΎΠΊΡΡΠΆΠ°ΡΡΠ΅ΠΉ ΠΏΠ°ΡΠ°ΡΠ·ΠΎΡΠ°Π³Π΅Π°Π»ΡΠ½ΠΎΠΉ ΠΊΠ»Π΅ΡΡΠ°ΡΠΊΠΈ. ΠΠ°Π½Π½ΡΠ΅ ΠΠ’ ΠΏΠΎΡΠ»ΡΠΆΠΈΠ»ΠΈ ΠΎΡΠ½ΠΎΠ²ΠΎΠΉ Π΄Π»Ρ ΠΎΠΏΡΠ΅Π΄Π΅Π»Π΅Π½ΠΈΡ ΠΎΠΏΡΠΈΠΌΠ°Π»ΡΠ½ΠΎΠΉ Π»Π΅ΡΠ΅Π±Π½ΠΎΠΉ ΡΠ°ΠΊΡΠΈΠΊΠΈ ΠΏΡΠΈ ΡΠΏΠΎΠ½ΡΠ°Π½Π½ΠΎΠΉ Π³Π΅ΠΌΠ°ΡΠΎΠΌΠ΅ ΠΏΠΈΡΠ΅Π²ΠΎΠ΄Π°. ΠΠΎΠ½ΡΠ΅ΡΠ²Π°ΡΠΈΠ²Π½Π°Ρ ΡΠ΅ΡΠ°ΠΏΠΈΡ ΡΠ²Π»ΡΠ»Π°ΡΡ ΠΎΡΠ½ΠΎΠ²Π½ΡΠΌ ΠΌΠ΅ΡΠΎΠ΄ΠΎΠΌ Π΅Π΅ Π»Π΅ΡΠ΅Π½ΠΈΡ. ΠΠ’-ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΠ΅ Π² Π΄ΠΈΠ½Π°ΠΌΠΈΠΊΠ΅ ΠΏΠΎΠ·Π²ΠΎΠ»ΠΈΠ»ΠΎ ΡΠ²ΠΎΠ΅Π²ΡΠ΅ΠΌΠ΅Π½Π½ΠΎ Π²ΡΡΠ²ΠΈΡΡ ΠΎΡΠ»ΠΎΠΆΠ½Π΅Π½ΠΈΡ ΡΠΏΠΎΠ½ΡΠ°Π½Π½ΠΎΠΉ Π³Π΅ΠΌΠ°ΡΠΎΠΌΡ ΠΏΠΈΡΠ΅Π²ΠΎΠ΄Π° (Π³Π΅ΠΌΠΎΡΠΎΡΠ°ΠΊΡ, ΠΏΠ΅ΡΡΠΎΡΠ°ΡΠΈΡ ΠΏΠΈΡΠ΅Π²ΠΎΠ΄Π°, ΠΈΠ½ΡΠΈΡΠΈΡΠΎΠ²Π°Π½ΠΈΠ΅ Π³Π΅ΠΌΠ°ΡΠΎΠΌΡ), ΡΡΠ΅Π±ΡΡΡΠΈΠ΅ Ρ
ΠΈΡΡΡΠ³ΠΈΡΠ΅ΡΠΊΠΎΠ³ΠΎ Π²ΠΌΠ΅ΡΠ°ΡΠ΅Π»ΡΡΡΠ²Π°.ΠΠ°ΠΊΠ»ΡΡΠ΅Π½ΠΈΠ΅. ΠΠ’ ΡΠ²Π»ΡΠ΅ΡΡΡ ΠΌΠ΅ΡΠΎΠ΄ΠΎΠΌ Π²ΡΠ±ΠΎΡΠ° ΠΏΡΠΈ Π΄ΠΈΠ°Π³Π½ΠΎΡΡΠΈΠΊΠ΅ ΡΠΏΠΎΠ½ΡΠ°Π½Π½ΠΎΠΉ Π³Π΅ΠΌΠ°ΡΠΎΠΌΡ ΠΏΠΈΡΠ΅Π²ΠΎΠ΄Π°, ΠΏΠΎΠ·Π²ΠΎΠ»ΡΡΡΠΈΠΌ ΠΏΡΠΎΠ²Π΅ΡΡΠΈ ΡΠ΅ΡΠΊΡΡ Π΄ΠΈΡΡΠ΅ΡΠ΅Π½ΡΠΈΠ°Π»ΡΠ½ΡΡ Π΄ΠΈΠ°Π³Π½ΠΎΡΡΠΈΠΊΡ Ρ Π½Π΅ΠΎΡΠ»ΠΎΠΆΠ½ΡΠΌΠΈ ΠΆΠΈΠ·Π½Π΅ΡΠ³ΡΠΎΠΆΠ°ΡΡΠΈΠΌΠΈ ΡΠΎΡΡΠΎΡΠ½ΠΈΡΠΌΠΈ. ΠΠ’-Π΄Π°Π½Π½ΡΠ΅ Π΄Π°ΡΡ Π²ΠΎΠ·ΠΌΠΎΠΆΠ½ΠΎΡΡΡ ΠΎΠ±ΠΎΡΠ½ΠΎΠ²Π°ΡΡ ΡΠ°ΠΊΡΠΈΠΊΡ Π»Π΅ΡΠ΅Π½ΠΈΡ ΠΈ ΠΎΡΠ΅Π½ΠΈΡΡ Π΄ΠΈΠ½Π°ΠΌΠΈΠΊΡ ΠΏΠ°ΡΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΎΠ³ΠΎ ΠΏΡΠΎΡΠ΅ΡΡΠ°
Π’ΡΠ°Π½ΡΠΏΠ»Π°Π½ΡΠ°ΡΠΈΡ Π»Π΅Π³ΠΊΠΈΡ Ρ ΠΏΠ°ΡΠΈΠ΅Π½ΡΠ° Ρ ΡΠΌΡΠΈΠ·Π΅ΠΌΠΎΠΉ Π½Π° ΡΠΎΠ½Π΅ Π΄Π΅ΡΠΈΡΠΈΡΠ° Ξ±1-Π°Π½ΡΠΈΡΡΠΈΠΏΡΠΈΠ½Π°
The condition of patients with chronic lung diseases is gradually deteriorating despite modern drug therapy and often progresses to severe respiratory failure. Thus, it is important to consider other options, including surgical methods, to help such patients. The aim of the study is to demonstrate potential additional pharmacological and surgical treatment algorithms for chronic obstructive pulmonary disease (COPD) associated with Ξ±1-anti-trypsin (A1AT) deficiency. Results. The analysis of long-term medical history (from the onset to the terminal stage of the respiratory failure) of a patient with A1AT deficiency was performed. Conclusion. Patients with COPD associated with A1AT deficiency require combination inhaled controller therapy and augmentation therapy with a1-proteinase inhibitor. Patients with terminal stage of the disease need lung transplantation unless they have any contraindications.ΠΠ΅ΡΠΌΠΎΡΡΡ Π½Π° ΡΠΎΠ²ΡΠ΅ΠΌΠ΅Π½Π½ΡΡ ΠΌΠ΅Π΄ΠΈΠΊΠ°ΠΌΠ΅Π½ΡΠΎΠ·Π½ΡΡ ΡΠ΅ΡΠ°ΠΏΠΈΡ, ΡΠΎΡΡΠΎΡΠ½ΠΈΠ΅ ΠΌΠ½ΠΎΠ³ΠΈΡ
ΠΏΠ°ΡΠΈΠ΅Π½ΡΠΎΠ² Ρ Ρ
ΡΠΎΠ½ΠΈΡΠ΅ΡΠΊΠΈΠΌΠΈ Π·Π°Π±ΠΎΠ»Π΅Π²Π°Π½ΠΈΡΠΌΠΈ Π»Π΅Π³ΠΊΠΈΡ
ΠΏΠΎΡΡΠ΅ΠΏΠ΅Π½Π½ΠΎ ΡΡ
ΡΠ΄ΡΠ°Π΅ΡΡΡ, Π½Π΅ΡΠ΅Π΄ΠΊΠΎ ΡΡΠΎ ΠΏΡΠΈΠ²ΠΎΠ΄ΠΈΡ ΠΊ ΡΠ°Π·Π²ΠΈΡΠΈΡ ΡΡΠΆΠ΅Π»ΠΎΠΉ Π΄ΡΡ
Π°ΡΠ΅Π»ΡΠ½ΠΎΠΉ Π½Π΅Π΄ΠΎΡΡΠ°ΡΠΎΡΠ½ΠΎΡΡΠΈ. ΠΡΠΈ ΡΡΠΎΠΌ Π²Π°ΠΆΠ½ΠΎ ΡΠ°ΡΡΠΌΠ°ΡΡΠΈΠ²Π°ΡΡ Π΄ΠΎΠΏΠΎΠ»Π½ΠΈΡΠ΅Π»ΡΠ½ΡΠ΅ Π²ΠΎΠ·ΠΌΠΎΠΆΠ½ΠΎΡΡΠΈ ΠΏΠΎΠΌΠΎΡΠΈ ΡΠ°ΠΊΠΈΠΌ ΠΏΠ°ΡΠΈΠ΅Π½ΡΠ°ΠΌ, Π² Ρ. Ρ. Ρ
ΠΈΡΡΡΠ³ΠΈΡΠ΅ΡΠΊΠΈΠ΅. Π¦Π΅Π»ΡΡ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΡ ΡΠ²ΠΈΠ»Π°ΡΡ Π΄Π΅ΠΌΠΎΠ½ΡΡΡΠ°ΡΠΈΡ Π²ΠΎΠ·ΠΌΠΎΠΆΠ½ΡΡ
Π΄ΠΎΠΏΠΎΠ»Π½ΠΈΡΠ΅Π»ΡΠ½ΡΡ
ΠΌΠ΅Π΄ΠΈΠΊΠ°ΠΌΠ΅Π½ΡΠΎΠ·Π½ΡΡ
ΠΈ Ρ
ΠΈΡΡΡΠ³ΠΈΡΠ΅ΡΠΊΠΈΡ
ΡΠΏΠΎΡΠΎΠ±ΠΎΠ² Π»Π΅ΡΠ΅Π½ΠΈΡ ΠΏΠ°ΡΠΈΠ΅Π½ΡΠΎΠ² Ρ Ρ
ΡΠΎΠ½ΠΈΡΠ΅ΡΠΊΠΎΠΉ ΠΎΠ±ΡΡΡΡΠΊΡΠΈΠ²Π½ΠΎΠΉ Π±ΠΎΠ»Π΅Π·Π½ΡΡ Π»Π΅Π³ΠΊΠΈΡ
(Π₯ΠΠΠ) Π½Π° ΡΠΎΠ½Π΅ Π΄Π΅ΡΠΈΡΠΈΡΠ° Ξ±1-Π°Π½ΡΠΈΡΡΠΈΠΏΡΠΈΠ½Π° (Π1ΠΠ’). Π Π΅Π·ΡΠ»ΡΡΠ°ΡΡ. ΠΡΠΏΠΎΠ»Π½Π΅Π½ Π°Π½Π°Π»ΠΈΠ· ΠΌΠ½ΠΎΠ³ΠΎΠ»Π΅ΡΠ½Π΅Π³ΠΎ Π°Π½Π°ΠΌΠ½Π΅Π·Π° ΠΏΠ°ΡΠΈΠ΅Π½ΡΠ° Ρ Π΄Π΅ΡΠΈΡΠΈΡΠΎΠΌ Π1ΠΠ’ ΠΎΡ Π΄Π΅Π±ΡΡΠ° Π·Π°Π±ΠΎΠ»Π΅Π²Π°Π½ΠΈΡ Π΄ΠΎ Π΄ΠΎΡΡΠΈΠΆΠ΅Π½ΠΈΡ ΡΠ΅ΡΠΌΠΈΠ½Π°Π»ΡΠ½ΠΎΠΉ ΡΡΠ°Π΄ΠΈΠΈ Π΄ΡΡ
Π°ΡΠ΅Π»ΡΠ½ΠΎΠΉ Π½Π΅Π΄ΠΎΡΡΠ°ΡΠΎΡΠ½ΠΎΡΡΠΈ. ΠΠ°ΠΊΠ»ΡΡΠ΅Π½ΠΈΠ΅. ΠΠ°ΡΠΈΠ΅Π½ΡΡ Ρ Π₯ΠΠΠ Π½Π° ΡΠΎΠ½Π΅ Π΄Π΅ΡΠΈΡΠΈΡΠ° Π1ΠΠ’ Π½ΡΠΆΠ΄Π°ΡΡΡΡ Π² ΠΊΠΎΠΌΠ±ΠΈΠ½ΠΈΡΠΎΠ²Π°Π½Π½ΠΎΠΉ ΠΈΠ½Π³Π°Π»ΡΡΠΈΠΎΠ½Π½ΠΎΠΉ Π±Π°Π·ΠΈΡΠ½ΠΎΠΉ ΡΠ΅ΡΠ°ΠΏΠΈΠΈ ΠΈ Π·Π°ΠΌΠ΅ΡΡΠΈΡΠ΅Π»ΡΠ½ΠΎΠΉ ΡΠ΅ΡΠ°ΠΏΠΈΠΈ ΠΈΠ½Π³ΠΈΠ±ΠΈΡΠΎΡΠΎΠΌ Ξ±1-ΠΏΡΠΎΡΠ΅ΠΈΠ½Π°Π·Ρ. ΠΠΎ Π΄ΠΎΡΡΠΈΠΆΠ΅Π½ΠΈΠΈ ΡΠ΅ΡΠΌΠΈΠ½Π°Π»ΡΠ½ΠΎΠΉ ΡΡΠ°Π΄ΠΈΠΈ Π·Π°Π±ΠΎΠ»Π΅Π²Π°Π½ΠΈΡ ΠΈ ΠΏΡΠΈ ΠΎΡΡΡΡΡΡΠ²ΠΈΠΈ ΠΏΡΠΎΡΠΈΠ²ΠΎΠΏΠΎΠΊΠ°Π·Π°Π½ΠΈΠΉ Π½Π΅ΠΎΠ±Ρ
ΠΎΠ΄ΠΈΠΌΠΎ Π²ΡΠΏΠΎΠ»Π½Π΅Π½ΠΈΠ΅ ΡΡΠ°Π½ΡΠΏΠ»Π°Π½ΡΠ°ΡΠΈΠΈ Π»Π΅Π³ΠΊΠΈΡ
Predictors of using extracorporeal membrane oxygenation in lung transplantation
Rationale. Lung transplantation is the only definitive treatment in end-stage pulmonary disease. Extracorporeal membrane oxygenation (ECMO) has been used during surgery in recent years as a replacement for respiratory function; ECMO, however, has some drawbacks: the presence of an extracorporeal circuit, the need for heparinization, potential thrombogenicity that underlies the risks of developing specific complications that worsen the transplantation prognosis. In this regard, it is relevant to study the factors that make it possible to predict the need in intraoperative ECMO in order to avoid its unjustified use.Purpose. To identify predictors for intraoperative use of ECMO in lung transplantation.Material and methods. The medical records of patients who underwent lung transplantation in the Sklifosovsky Research Institute for Emergency Medicine from May 2011 to July 2017 were retrospectively reviewed. Forty nine bilateral lung transplantations were made where 15 patients (30.6%) had lung transplantation performed without ECMO, and 34 (69.4%) underwent lung transplantation and ECMO. A central veno-arterial connection was used in all patients. The study analyzed various factors of patient condition at baseline and identified the most significant of them that enabled to predict the need of ECMO use at surgery with a high degree of probability, avoiding episodes of gas exchange and hemodynamic impairments, the prolongation of surgery, and, therefore, the graft ischemia time.Results. As assessed in this study, pulmonary hypertension was the only predictor of an increased likelihood of using ECMO. The probability of connection to ECMO statistically significantly increased in the patients with systolic pulmonary artery pressure higher 50 mm Hg (p<0.05).Conclusion. The presence of pulmonary hypertension > 50 mm Hg determines the preventive use of ECMO during lung transplantation, which should reduce the number of uncontrolled emergencies during the main stages of surgical intervention; in all other cases, ECMO should be connected basing either on the pulmonary artery compression test results or when indicated