5 research outputs found

    ΠŸΠ°Ρ€Π°Π²Π΅Ρ€Ρ‚Π΅Π±Ρ€Π°Π»ΡŒΠ½Π°Ρ Π±Π»ΠΎΠΊΠ°Π΄Π° ΠΏΡ€ΠΈ Π»Π΅Ρ‡Π΅Π½ΠΈΠΈ ΠΏΠ°Ρ†ΠΈΠ΅Π½Ρ‚ΠΎΠ² с Π·Π°ΠΊΡ€Ρ‹Ρ‚ΠΎΠΉ Ρ‚Ρ€Π°Π²ΠΌΠΎΠΉ Π³Ρ€ΡƒΠ΄ΠΈ

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    The study was conducted in the Thoracoabdominal Department of the N.V. Sklifosovsky Research Institute for Emergency Medicine to explore the role of paravertebral block in the treatment of blunt chest trauma. The study included 715 patients with isolated chest trauma hospitalized between January 1, 2020 and August 2021. 55 patients received analgesic therapy in the form of paravertebral block. The comparison group included 660 patients who did not undergo paravertebral block, in their case pain relief was provided by systemic administration of analgesics. The compared groups did not differ significantly in sex and age composition. There were also no differences in the frequency of chronic diseases and interpleural complications. There were no significant complications during the block. The comparison revealed a significant decrease in the incidence of pleurisy and a shorter length of stay in hospital. Paravertebral block is an effective and safe method of pain management for patients with blunt chest trauma. The use of this technique reduces the incidence of post-traumatic pleurisy and duration of hospitalization.ИсслСдованиС ΠΏΡ€ΠΎΠ²Π΅Π΄Π΅Π½ΠΎ Π² Ρ‚ΠΎΡ€Π°ΠΊΠΎΠ°Π±Π΄ΠΎΠΌΠΈΠ½Π°Π»ΡŒΠ½ΠΎΠΌ ΠΎΡ‚Π΄Π΅Π»Π΅Π½ΠΈΠΈ НИИ БП ΠΈΠΌ. Н.Π’. Бклифосовского с Ρ†Π΅Π»ΡŒΡŽ изучСния значСния ΠΏΠ°Ρ€Π°Π²Π΅Ρ€Ρ‚Π΅Π±Ρ€Π°Π»ΡŒΠ½ΠΎΠΉ Π±Π»ΠΎΠΊΠ°Π΄Ρ‹. Π‘Ρ‹Π»ΠΎ Π²ΠΊΠ»ΡŽΡ‡Π΅Π½ΠΎ 715 ΠΏΠ°Ρ†ΠΈΠ΅Π½Ρ‚ΠΎΠ² с ΠΈΠ·ΠΎΠ»ΠΈΡ€ΠΎΠ²Π°Π½Π½ΠΎΠΉ Ρ‚Ρ€Π°Π²ΠΌΠΎΠΉ Π³Ρ€ΡƒΠ΄ΠΈ, госпитализированных Π² экстрСнном порядкС Π² ΠΏΠ΅Ρ€ΠΈΠΎΠ΄ с 1 января 2020 ΠΏΠΎ август 2021 Π³ΠΎΠ΄Π°; 55 ΠΏΠ°Ρ†ΠΈΠ΅Π½Ρ‚ΠΎΠ² Π² Ρ…ΠΎΠ΄Π΅ лСчСния ΠΏΠΎΠ»ΡƒΡ‡ΠΈΠ»ΠΈ ΠΎΠ±Π΅Π·Π±ΠΎΠ»ΠΈΠ²Π°ΡŽΡ‰ΡƒΡŽ Ρ‚Π΅Ρ€Π°ΠΏΠΈΡŽ Π² Π²ΠΈΠ΄Π΅ ΠΏΠ°Ρ€Π°Π²Π΅Ρ€Ρ‚Π΅Π±Ρ€Π°Π»ΡŒΠ½ΠΎΠΉ Π±Π»ΠΎΠΊΠ°Π΄Ρ‹. Π’ Π³Ρ€ΡƒΠΏΠΏΡƒ сравнСния Π²ΠΊΠ»ΡŽΡ‡ΠΈΠ»ΠΈ 660 ΠΏΠ°Ρ†ΠΈΠ΅Π½Ρ‚ΠΎΠ², ΠΊΠΎΡ‚ΠΎΡ€Ρ‹ΠΌ Π½Π΅ выполняли ΠΏΡ€ΠΎΠ²ΠΎΠ΄Π½ΠΈΠΊΠΎΠ²ΡƒΡŽ Π±Π»ΠΎΠΊΠ°Π΄Ρƒ, ΠΎΠ±Π΅Π·Π±ΠΎΠ»ΠΈΠ²Π°Π½ΠΈΠ΅ обСспСчивали систСмным Π²Π²Π΅Π΄Π΅Π½ΠΈΠ΅ΠΌ Π°Π½Π°Π»ΡŒΠ³Π΅Ρ‚ΠΈΠΊΠΎΠ². Π‘Ρ€Π°Π²Π½ΠΈΠ²Π°Π΅ΠΌΡ‹Π΅ Π³Ρ€ΡƒΠΏΠΏΡ‹ Π·Π½Π°Ρ‡ΠΈΠΌΠΎ Π½Π΅ ΠΎΡ‚Π»ΠΈΡ‡Π°Π»ΠΈΡΡŒ ΠΏΠΎ ΠΏΠΎΠ»ΠΎΠ²ΠΎΠΌΡƒ ΠΈ возрастному составу. ΠžΡ‚Π»ΠΈΡ‡ΠΈΠΉ Π² частотС хроничСских Π·Π°Π±ΠΎΠ»Π΅Π²Π°Π½ΠΈΠΉ ΠΈ ΠΈΠ½Ρ‚Ρ€Π°ΠΏΠ»Π΅Π²Ρ€Π°Π»ΡŒΠ½Ρ‹Ρ… ослоТнСний Ρ‚Π°ΠΊΠΆΠ΅ Π½Π΅ Π±Ρ‹Π»ΠΎ. Π—Π½Π°Ρ‡ΠΈΠΌΡ‹Ρ… ослоТнСний ΠΏΡ€ΠΈ Π²Ρ‹ΠΏΠΎΠ»Π½Π΅Π½ΠΈΠΈ Π±Π»ΠΎΠΊΠ°Π΄Ρ‹ Π½Π΅ ΠΎΡ‚ΠΌΠ΅Ρ‡Π°Π»ΠΎΡΡŒ. ΠŸΡ€ΠΈ сравнСнии выявлСно достовСрноС ΡƒΠΌΠ΅Π½ΡŒΡˆΠ΅Π½ΠΈΠ΅ частоты ΠΏΠ»Π΅Π²Ρ€ΠΈΡ‚Π° ΠΈ Π±ΠΎΠ»Π΅Π΅ ΠΊΠΎΡ€ΠΎΡ‚ΠΊΠΎΠ΅ врСмя нахоТдСния Π² стационарС. ΠŸΠ°Ρ€Π°Π²Π΅Ρ€Ρ‚Π΅Π±Ρ€Π°Π»ΡŒΠ½Π°Ρ Π±Π»ΠΎΠΊΠ°Π΄Π° являСтся эффСктивным ΠΈ бСзопасным ΠΌΠ΅Ρ‚ΠΎΠ΄ΠΎΠΌ обСзболивания ΠΏΠ°Ρ†ΠΈΠ΅Π½Ρ‚ΠΎΠ² с Π·Π°ΠΊΡ€Ρ‹Ρ‚ΠΎΠΉ Ρ‚Ρ€Π°Π²ΠΌΠΎΠΉ Π³Ρ€ΡƒΠ΄ΠΈ. ИспользованиС этой ΠΌΠ΅Ρ‚ΠΎΠ΄ΠΈΠΊΠΈ сниТаСт частоту развития посттравматичСского ΠΏΠ»Π΅Π²Ρ€ΠΈΡ‚Π° ΠΈ ускоряСт выписку Π±ΠΎΠ»ΡŒΠ½Ρ‹Ρ…

    ΠšΠΎΠΌΠΏΡŒΡŽΡ‚Π΅Ρ€Π½Π°Ρ томография ΠΏΡ€ΠΈ спонтанной Π³Π΅ΠΌΠ°Ρ‚ΠΎΠΌΠ΅ ΠΏΠΈΡ‰Π΅Π²ΠΎΠ΄Π°: Π½Π°Π΄Π΅ΠΆΠ½ΠΎΠ΅ сопровоТдСниС ΠΎΡ‚ диагностики Π΄ΠΎ выздоровлСния

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    The purpose of the study. To study the possibilities of computed tomography (CT) in the diagnosis of spontaneous hematoma of the esophagus, including in the process of dynamic observation.Materials and methods. A retrospective analysis of CT results in 11 patients with spontaneous esophageal hematoma treated at the N.V. Sklifosovsky Research Institute of SP in the period 2005–2020 is presented. All patients underwent a comprehensive laboratory and instrumental examination, including CT. CT studies were performed with oral and intravenous bolus contrast, primarily at admission and in dynamics.Results. In all cases, according to CT data, acute pathology of the aorta, rupture of the esophagus were excluded and signs of spontaneous hematoma of the esophagus were revealed. CT semiotics of esophageal hematoma was analyzed with quantitative treatment of changes in density, linear dimensions and volume. CT semiotics analysis also revealed the volumetric effect of hematoma on surrounding organs and structures, accumulation of blood in the pleural cavities, and verified signs of infection of hematoma with inflammatory changes in the surrounding paraesophageal tissue. CT data served as the basis for determining the optimal treatment tactics for spontaneous esophageal hematoma. Conservative therapy was the main method of her treatment. CT examination in dynamics allowed timely detection of complications of spontaneous hematoma of the esophagus (hemothorax, perforation of the esophagus, infection of the hematoma) requiring surgical intervention.Conclusion. CT is the method of choice in the diagnosis of spontaneous hematoma of the esophagus, which allows for a clear differential diagnosis with urgent life-threatening conditions. CT data make it possible to justify treatment tactics and assess the dynamics of the pathological process.ЦСль исслСдования: ΠΈΠ·ΡƒΡ‡ΠΈΡ‚ΡŒ возмоТности ΠΊΠΎΠΌΠΏΡŒΡŽΡ‚Π΅Ρ€Π½ΠΎΠΉ Ρ‚ΠΎΠΌΠΎΠ³Ρ€Π°Ρ„ΠΈΠΈ (КВ) Π² диагностикС спонтанной Π³Π΅ΠΌΠ°Ρ‚ΠΎΠΌΡ‹ ΠΏΠΈΡ‰Π΅Π²ΠΎΠ΄Π°, Π² Ρ‚ΠΎΠΌ числС Π² процСссС динамичСского наблюдСния.ΠœΠ°Ρ‚Π΅Ρ€ΠΈΠ°Π» ΠΈ ΠΌΠ΅Ρ‚ΠΎΠ΄Ρ‹. ΠŸΡ€Π΅Π΄ΡΡ‚Π°Π²Π»Π΅Π½ рСтроспСктивный Π°Π½Π°Π»ΠΈΠ· Ρ€Π΅Π·ΡƒΠ»ΡŒΡ‚Π°Ρ‚ΠΎΠ² КВ Ρƒ 11 ΠΏΠ°Ρ†ΠΈΠ΅Π½Ρ‚ΠΎΠ² со спонтанной Π³Π΅ΠΌΠ°Ρ‚ΠΎΠΌΠΎΠΉ ΠΏΠΈΡ‰Π΅Π²ΠΎΠ΄Π°, Π½Π°Ρ…ΠΎΠ΄ΠΈΠ²ΡˆΠΈΡ…ΡΡ Π½Π° Π»Π΅Ρ‡Π΅Π½ΠΈΠΈ Π² НИИ БП ΠΈΠΌ. Н.Π’. Бклифосовского Π² ΠΏΠ΅Ρ€ΠΈΠΎΠ΄ 2005–2020 Π³Π³. ВсСм ΠΏΠ°Ρ†ΠΈΠ΅Π½Ρ‚Π°ΠΌ Π±Ρ‹Π»ΠΎ Π²Ρ‹ΠΏΠΎΠ»Π½Π΅Π½ΠΎ комплСксноС Π»Π°Π±ΠΎΡ€Π°Ρ‚ΠΎΡ€Π½ΠΎ-ΠΈΠ½ΡΡ‚Ρ€ΡƒΠΌΠ΅Π½Ρ‚Π°Π»ΡŒΠ½ΠΎΠ΅ обслСдованиС, Π²ΠΊΠ»ΡŽΡ‡Π°Π²ΡˆΠ΅Π΅ КВ с ΠΏΠ΅Ρ€ΠΎΡ€Π°Π»ΡŒΠ½Ρ‹ΠΌ ΠΈ Π²Π½ΡƒΡ‚Ρ€ΠΈΠ²Π΅Π½Π½Ρ‹ΠΌ Π±ΠΎΠ»ΡŽΡΠ½Ρ‹ΠΌ контрастированиСм, ΠΊΠ°ΠΊ ΠΏΠ΅Ρ€Π²ΠΈΡ‡Π½ΠΎ ΠΏΡ€ΠΈ поступлСнии, Ρ‚Π°ΠΊ ΠΈ Π² Π΄ΠΈΠ½Π°ΠΌΠΈΠΊΠ΅.Π Π΅Π·ΡƒΠ»ΡŒΡ‚Π°Ρ‚Ρ‹. Π’ΠΎ всСх случаях ΠΏΠΎ Π΄Π°Π½Π½Ρ‹ΠΌ КВ Π±Ρ‹Π»ΠΈ ΠΈΡΠΊΠ»ΡŽΡ‡Π΅Π½Ρ‹ острая патология Π°ΠΎΡ€Ρ‚Ρ‹, Ρ€Π°Π·Ρ€Ρ‹Π² ΠΏΠΈΡ‰Π΅Π²ΠΎΠ΄Π° ΠΈ выявлСны ΠΏΡ€ΠΈΠ·Π½Π°ΠΊΠΈ спонтанной Π³Π΅ΠΌΠ°Ρ‚ΠΎΠΌΡ‹ ΠΏΠΈΡ‰Π΅Π²ΠΎΠ΄Π°. ΠŸΡ€ΠΎΠ°Π½Π°Π»ΠΈΠ·ΠΈΡ€ΠΎΠ²Π°Π½Π° КВ-сСмиотика Π³Π΅ΠΌΠ°Ρ‚ΠΎΠΌΡ‹ ΠΏΠΈΡ‰Π΅Π²ΠΎΠ΄Π° с количСствСнной ΠΎΠ±Ρ€Π°Π±ΠΎΡ‚ΠΊΠΎΠΉ ΠΈΠ·ΠΌΠ΅Π½Π΅Π½ΠΈΠΉ ΠΏΠΎ плотности, Π»ΠΈΠ½Π΅ΠΉΠ½Ρ‹ΠΌ Ρ€Π°Π·ΠΌΠ΅Ρ€Π°ΠΌ ΠΈ ΠΎΠ±ΡŠΠ΅ΠΌΡƒ. Анализ КВ-сСмиотики Ρ‚Π°ΠΊΠΆΠ΅ ΠΏΠΎΠ·Π²ΠΎΠ»ΠΈΠ» Π²Ρ‹ΡΠ²ΠΈΡ‚ΡŒ объСмноС воздСйствиС Π³Π΅ΠΌΠ°Ρ‚ΠΎΠΌΡ‹ Π½Π° ΠΎΠΊΡ€ΡƒΠΆΠ°ΡŽΡ‰ΠΈΠ΅ ΠΎΡ€Π³Π°Π½Ρ‹ ΠΈ структуры, скоплСниС ΠΊΡ€ΠΎΠ²ΠΈ Π² ΠΏΠ»Π΅Π²Ρ€Π°Π»ΡŒΠ½Ρ‹Ρ… полостях, Π²Π΅Ρ€ΠΈΡ„ΠΈΡ†ΠΈΡ€ΠΎΠ²Π°Ρ‚ΡŒ ΠΏΡ€ΠΈΠ·Π½Π°ΠΊΠΈ инфицирования Π³Π΅ΠΌΠ°Ρ‚ΠΎΠΌΡ‹ с Π²ΠΎΡΠΏΠ°Π»ΠΈΡ‚Π΅Π»ΡŒΠ½Ρ‹ΠΌΠΈ измСнСниями ΠΎΠΊΡ€ΡƒΠΆΠ°ΡŽΡ‰Π΅ΠΉ ΠΏΠ°Ρ€Π°ΡΠ·ΠΎΡ„Π°Π³Π΅Π°Π»ΡŒΠ½ΠΎΠΉ ΠΊΠ»Π΅Ρ‚Ρ‡Π°Ρ‚ΠΊΠΈ. Π”Π°Π½Π½Ρ‹Π΅ КВ послуТили основой для опрСдСлСния ΠΎΠΏΡ‚ΠΈΠΌΠ°Π»ΡŒΠ½ΠΎΠΉ Π»Π΅Ρ‡Π΅Π±Π½ΠΎΠΉ Ρ‚Π°ΠΊΡ‚ΠΈΠΊΠΈ ΠΏΡ€ΠΈ спонтанной Π³Π΅ΠΌΠ°Ρ‚ΠΎΠΌΠ΅ ΠΏΠΈΡ‰Π΅Π²ΠΎΠ΄Π°. ΠšΠΎΠ½ΡΠ΅Ρ€Π²Π°Ρ‚ΠΈΠ²Π½Π°Ρ тСрапия являлась основным ΠΌΠ΅Ρ‚ΠΎΠ΄ΠΎΠΌ Π΅Π΅ лСчСния. КВ-исслСдованиС Π² Π΄ΠΈΠ½Π°ΠΌΠΈΠΊΠ΅ ΠΏΠΎΠ·Π²ΠΎΠ»ΠΈΠ»ΠΎ своСврСмСнно Π²Ρ‹ΡΠ²ΠΈΡ‚ΡŒ ослоТнСния спонтанной Π³Π΅ΠΌΠ°Ρ‚ΠΎΠΌΡ‹ ΠΏΠΈΡ‰Π΅Π²ΠΎΠ΄Π° (гСмоторакс, пСрфорация ΠΏΠΈΡ‰Π΅Π²ΠΎΠ΄Π°, ΠΈΠ½Ρ„ΠΈΡ†ΠΈΡ€ΠΎΠ²Π°Π½ΠΈΠ΅ Π³Π΅ΠΌΠ°Ρ‚ΠΎΠΌΡ‹), Ρ‚Ρ€Π΅Π±ΡƒΡŽΡ‰ΠΈΠ΅ хирургичСского Π²ΠΌΠ΅ΡˆΠ°Ρ‚Π΅Π»ΡŒΡΡ‚Π²Π°.Π—Π°ΠΊΠ»ΡŽΡ‡Π΅Π½ΠΈΠ΅. КВ являСтся ΠΌΠ΅Ρ‚ΠΎΠ΄ΠΎΠΌ Π²Ρ‹Π±ΠΎΡ€Π° ΠΏΡ€ΠΈ диагностикС спонтанной Π³Π΅ΠΌΠ°Ρ‚ΠΎΠΌΡ‹ ΠΏΠΈΡ‰Π΅Π²ΠΎΠ΄Π°, ΠΏΠΎΠ·Π²ΠΎΠ»ΡΡŽΡ‰ΠΈΠΌ провСсти Ρ‡Π΅Ρ‚ΠΊΡƒΡŽ Π΄ΠΈΡ„Ρ„Π΅Ρ€Π΅Π½Ρ†ΠΈΠ°Π»ΡŒΠ½ΡƒΡŽ диагностику с Π½Π΅ΠΎΡ‚Π»ΠΎΠΆΠ½Ρ‹ΠΌΠΈ ΠΆΠΈΠ·Π½Π΅ΡƒΠ³Ρ€ΠΎΠΆΠ°ΡŽΡ‰ΠΈΠΌΠΈ состояниями. КВ-Π΄Π°Π½Π½Ρ‹Π΅ Π΄Π°ΡŽΡ‚ Π²ΠΎΠ·ΠΌΠΎΠΆΠ½ΠΎΡΡ‚ΡŒ ΠΎΠ±ΠΎΡΠ½ΠΎΠ²Π°Ρ‚ΡŒ Ρ‚Π°ΠΊΡ‚ΠΈΠΊΡƒ лСчСния ΠΈ ΠΎΡ†Π΅Π½ΠΈΡ‚ΡŒ Π΄ΠΈΠ½Π°ΠΌΠΈΠΊΡƒ патологичСского процСсса

    Врансплантация Π»Π΅Π³ΠΊΠΈΡ… Ρƒ ΠΏΠ°Ρ†ΠΈΠ΅Π½Ρ‚Π° с эмфизСмой Π½Π° Ρ„ΠΎΠ½Π΅ Π΄Π΅Ρ„ΠΈΡ†ΠΈΡ‚Π° Ξ±1-антитрипсина

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    The condition of patients with chronic lung diseases is gradually deteriorating despite modern drug therapy and often progresses to severe respiratory failure. Thus, it is important to consider other options, including surgical methods, to help such patients. The aim of the study is to demonstrate potential additional pharmacological and surgical treatment algorithms for chronic obstructive pulmonary disease (COPD) associated with Ξ±1-anti-trypsin (A1AT) deficiency. Results. The analysis of long-term medical history (from the onset to the terminal stage of the respiratory failure) of a patient with A1AT deficiency was performed. Conclusion. Patients with COPD associated with A1AT deficiency require combination inhaled controller therapy and augmentation therapy with a1-proteinase inhibitor. Patients with terminal stage of the disease need lung transplantation unless they have any contraindications.НСсмотря Π½Π° ΡΠΎΠ²Ρ€Π΅ΠΌΠ΅Π½Π½ΡƒΡŽ ΠΌΠ΅Π΄ΠΈΠΊΠ°ΠΌΠ΅Π½Ρ‚ΠΎΠ·Π½ΡƒΡŽ Ρ‚Π΅Ρ€Π°ΠΏΠΈΡŽ, состояниС ΠΌΠ½ΠΎΠ³ΠΈΡ… ΠΏΠ°Ρ†ΠΈΠ΅Π½Ρ‚ΠΎΠ² с хроничСскими заболСваниями Π»Π΅Π³ΠΊΠΈΡ… постСпСнно ΡƒΡ…ΡƒΠ΄ΡˆΠ°Π΅Ρ‚ΡΡ, Π½Π΅Ρ€Π΅Π΄ΠΊΠΎ это ΠΏΡ€ΠΈΠ²ΠΎΠ΄ΠΈΡ‚ ΠΊ Ρ€Π°Π·Π²ΠΈΡ‚ΠΈΡŽ тяТСлой Π΄Ρ‹Ρ…Π°Ρ‚Π΅Π»ΡŒΠ½ΠΎΠΉ нСдостаточности. ΠŸΡ€ΠΈ этом Π²Π°ΠΆΠ½ΠΎ Ρ€Π°ΡΡΠΌΠ°Ρ‚Ρ€ΠΈΠ²Π°Ρ‚ΡŒ Π΄ΠΎΠΏΠΎΠ»Π½ΠΈΡ‚Π΅Π»ΡŒΠ½Ρ‹Π΅ возмоТности ΠΏΠΎΠΌΠΎΡ‰ΠΈ Ρ‚Π°ΠΊΠΈΠΌ ΠΏΠ°Ρ†ΠΈΠ΅Π½Ρ‚Π°ΠΌ, Π² Ρ‚. Ρ‡. хирургичСскиС. ЦСлью исслСдования явилась дСмонстрация Π²ΠΎΠ·ΠΌΠΎΠΆΠ½Ρ‹Ρ… Π΄ΠΎΠΏΠΎΠ»Π½ΠΈΡ‚Π΅Π»ΡŒΠ½Ρ‹Ρ… ΠΌΠ΅Π΄ΠΈΠΊΠ°ΠΌΠ΅Π½Ρ‚ΠΎΠ·Π½Ρ‹Ρ… ΠΈ хирургичСских способов лСчСния ΠΏΠ°Ρ†ΠΈΠ΅Π½Ρ‚ΠΎΠ² с хроничСской обструктивной болСзнью Π»Π΅Π³ΠΊΠΈΡ… (Π₯ΠžΠ‘Π›) Π½Π° Ρ„ΠΎΠ½Π΅ Π΄Π΅Ρ„ΠΈΡ†ΠΈΡ‚Π° Ξ±1-антитрипсина (А1АВ). Π Π΅Π·ΡƒΠ»ΡŒΡ‚Π°Ρ‚Ρ‹. Π’Ρ‹ΠΏΠΎΠ»Π½Π΅Π½ Π°Π½Π°Π»ΠΈΠ· ΠΌΠ½ΠΎΠ³ΠΎΠ»Π΅Ρ‚Π½Π΅Π³ΠΎ Π°Π½Π°ΠΌΠ½Π΅Π·Π° ΠΏΠ°Ρ†ΠΈΠ΅Π½Ρ‚Π° с Π΄Π΅Ρ„ΠΈΡ†ΠΈΡ‚ΠΎΠΌ А1АВ ΠΎΡ‚ Π΄Π΅Π±ΡŽΡ‚Π° заболСвания Π΄ΠΎ достиТСния Ρ‚Π΅Ρ€ΠΌΠΈΠ½Π°Π»ΡŒΠ½ΠΎΠΉ стадии Π΄Ρ‹Ρ…Π°Ρ‚Π΅Π»ΡŒΠ½ΠΎΠΉ нСдостаточности. Π—Π°ΠΊΠ»ΡŽΡ‡Π΅Π½ΠΈΠ΅. ΠŸΠ°Ρ†ΠΈΠ΅Π½Ρ‚Ρ‹ с Π₯ΠžΠ‘Π› Π½Π° Ρ„ΠΎΠ½Π΅ Π΄Π΅Ρ„ΠΈΡ†ΠΈΡ‚Π° А1АВ Π½ΡƒΠΆΠ΄Π°ΡŽΡ‚ΡΡ Π² ΠΊΠΎΠΌΠ±ΠΈΠ½ΠΈΡ€ΠΎΠ²Π°Π½Π½ΠΎΠΉ ингаляционной базисной Ρ‚Π΅Ρ€Π°ΠΏΠΈΠΈ ΠΈ Π·Π°ΠΌΠ΅ΡΡ‚ΠΈΡ‚Π΅Π»ΡŒΠ½ΠΎΠΉ Ρ‚Π΅Ρ€Π°ΠΏΠΈΠΈ ΠΈΠ½Π³ΠΈΠ±ΠΈΡ‚ΠΎΡ€ΠΎΠΌ Ξ±1-ΠΏΡ€ΠΎΡ‚Π΅ΠΈΠ½Π°Π·Ρ‹. По достиТСнии Ρ‚Π΅Ρ€ΠΌΠΈΠ½Π°Π»ΡŒΠ½ΠΎΠΉ стадии заболСвания ΠΈ ΠΏΡ€ΠΈ отсутствии ΠΏΡ€ΠΎΡ‚ΠΈΠ²ΠΎΠΏΠΎΠΊΠ°Π·Π°Π½ΠΈΠΉ Π½Π΅ΠΎΠ±Ρ…ΠΎΠ΄ΠΈΠΌΠΎ Π²Ρ‹ΠΏΠΎΠ»Π½Π΅Π½ΠΈΠ΅ трансплантации Π»Π΅Π³ΠΊΠΈΡ…

    Predictors of using extracorporeal membrane oxygenation in lung transplantation

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    Rationale. Lung transplantation is the only definitive treatment in end-stage pulmonary disease. Extracorporeal membrane oxygenation (ECMO) has been used during surgery in recent years as a replacement for respiratory function; ECMO, however, has some drawbacks: the presence of an extracorporeal circuit, the need for heparinization, potential thrombogenicity that underlies the risks of developing specific complications that worsen the transplantation prognosis. In this regard, it is relevant to study the factors that make it possible to predict the need in intraoperative ECMO in order to avoid its unjustified use.Purpose. To identify predictors for intraoperative use of ECMO in lung transplantation.Material and methods. The medical records of patients who underwent lung transplantation in the Sklifosovsky Research Institute for Emergency Medicine from May 2011 to July 2017 were retrospectively reviewed. Forty nine bilateral lung transplantations were made where 15 patients (30.6%) had lung transplantation performed without ECMO, and 34 (69.4%) underwent lung transplantation and ECMO. A central veno-arterial connection was used in all patients. The study analyzed various factors of patient condition at baseline and identified the most significant of them that enabled to predict the need of ECMO use at surgery with a high degree of probability, avoiding episodes of gas exchange and hemodynamic impairments, the prolongation of surgery, and, therefore, the graft ischemia time.Results. As assessed in this study, pulmonary hypertension was the only predictor of an increased likelihood of using ECMO. The probability of connection to ECMO statistically significantly increased in the patients with systolic pulmonary artery pressure higher 50 mm Hg (p<0.05).Conclusion. The presence of pulmonary hypertension > 50 mm Hg determines the preventive use of ECMO during lung transplantation, which should reduce the number of uncontrolled emergencies during the main stages of surgical intervention; in all other cases, ECMO should be connected basing either on the pulmonary artery compression test results or when indicated
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