Spontaneous Local Gamma Oscillation Selectively Enhances Neural Network Responsiveness

Synchronized oscillation is very commonly observed in many neuronal systems and might play an important role in the response properties of the system. We have studied how the spontaneous oscillatory activity affects the responsiveness of a neuronal network, using a neural network model of the visual cortex built from Hodgkin-Huxley type excitatory (E-) and inhibitory (I-) neurons. When the isotropic local E-I and I-E synaptic connections were sufficiently strong, the network commonly generated gamma frequency oscillatory firing patterns in response to random feed-forward (FF) input spikes. This spontaneous oscillatory network activity injects a periodic local current that could amplify a weak synaptic input and enhance the network's responsiveness. When E-E connections were added, we found that the strength of oscillation can be modulated by varying the FF input strength without any changes in single neuron properties or interneuron connectivity. The response modulation is proportional to the oscillation strength, which leads to self-regulation such that the cortical network selectively amplifies various FF inputs according to its strength, without requiring any adaptation mechanism. We show that this selective cortical amplification is controlled by E-E cell interactions. We also found that this response amplification is spatially localized, which suggests that the responsiveness modulation may also be spatially selective. This suggests a generalized mechanism by which neural oscillatory activity can enhance the selectivity of a neural network to FF inputs

The response of a classical Hodgkin–Huxley neuron to an inhibitory input pulse

A population of uncoupled neurons can often be brought close to synchrony by a single strong inhibitory input pulse affecting all neurons equally. This mechanism is thought to underlie some brain rhythms, in particular gamma frequency (30–80 Hz) oscillations in the hippocampus and neocortex. Here we show that synchronization by an inhibitory input pulse often fails for populations of classical Hodgkin–Huxley neurons. Our reasoning suggests that in general, synchronization by inhibitory input pulses can fail when the transition of the target neurons from rest to spiking involves a Hopf bifurcation, especially when inhibition is shunting, not hyperpolarizing. Surprisingly, synchronization is more likely to fail when the inhibitory pulse is stronger or longer-lasting. These findings have potential implications for the question which neurons participate in brain rhythms, in particular in gamma oscillations

Structure Stability of Cultivated Soils from Semi-Arid Region: Comparing the Effects of Land Use and Anionic Polyacrylamide Application

The Sustainable Development Goals of the United Nations call for applying soil management practices that contribute land degradation neutrality. Our objectives were to investigate the effect of (i) soil management—conventional tillage (CT under crop) and no-tillage (NT under grass)—and (ii) an amendment (polyacrylamide (PAM)) application on the structure stability indices of soils from a semi-arid region. Two sets of experiments were conducted using the high-energy moisture characteristic (HEMC) method for the assessment of (i) land-use type (CT vs. NT) in soils (30 samples) varying in texture, and (ii) the effect of six PAM concentrations (0, 10, 25, 50, 100, and 200 mg L−1) on three typical soils (sandy clay loam, clay loam, and clay) under CT management; then, the contributions of PAM concentration (CT) and NT were compared. Water retention curves of samples were obtained at a matric potential from 0 to −5.0 J kg−1 and characterized by a modified van Genuchten model that yields (i) model parameters α and n, and (ii) a soil structure stability index (SI). The treatments affected the shape of the water retention curves. Change of land use from CT to NT and PAM application to CT soil increased the SI and ɑ, and decreased n compared to CT-managed soils. The magnitude of the NT and PAM effect was inversely related to soil clay content. CT-managed soils treated with a low PAM rate (10–25 mg L−1) gave SI comparable to that obtained for the NT-managed soils, while CT-managed soils treated with a high PAM rate (50–200 mg L−1) yielded 1.3–2.0 and 2–4 times higher SI than that for NT and CT-managed soils, respectively. Our findings suggest that both the change of land use to NT or the addition of small amounts of PAM are viable alternatives for stabilizing CT-managed weakly alkaline semi-arid soils, whose soil structure stability is a priori limited

Effectiveness of Polyacrylamide in Reducing Runoff and Soil Loss under Consecutive Rainfall Storms

The use of anionic polyacrylamide (PAM) as a soil conditioner could help prevent soil loss by water. In this study, we determined the effective granular PAM rate that best reduces runoff and soil loss from Oxisols. Furthermore, the effectiveness of the selected PAM rate was tested by applying it in a mixture with gypsum (G) or lime (L). The study was conducted in two phases: (i) Dry PAM rates of 0 (C), 20 kg ha−1 (P20), 40 kg ha−1 (P40), and 60 kg ha−1 (P60) were applied onto soil surface and run for six consecutive rainfall storms of 70 mm h−1 intensity for 1 h duration, and the effective PAM rate was selected; and (ii) G (4 t ha−1) or L (2 t ha−1) were applied alone or mixed with the selected PAM rate. The P20 was found to be effective in reducing runoff in the beginning while P40 and P60 were more effective starting from the third storm through the end of the consecutive storms, but with no statistically significant difference between P40 and P60. Hence, P40 was selected as the most suitable rate for the given test soil and rainfall pattern. On the other hand, the mixed application of P40 with G or L increased infiltration rate (IR) in the first two storms through improving soil solution viscosity. However, effectiveness of the mixtures had diminished by various degrees as rain progressed, as compared to P40 alone, which could be attributed to the rate and properties of G and L. In conclusion, the variation in effectiveness of PAM rates in reducing runoff with storm duration could indicate that the effective rates shall be selected based on the climatic region in that lower rates for the short rains or higher rates for elongated rains. Moreover, combined application of PAM with L could offer a good option to both fairly reduce soil erosion and improve land productivity especially in acidic soils like Oxisols, which requires further field verification