BIOINFORMATICS ParIS Genome Rearrangement server

Summary: ParIS Genome Rearrangement is a web server for a Bayesian analysis of unichromosomal genome pairs. The underlying model allows inversions, transpositions and inverted transpositions. The server generates a Markov chain using a Partial Importance Sampler technique, and samples trajectories of mutations from this chain. The user can specify several marginalizations to the posterior: the posterior distribution of number of mutations needed to transform one genome to another, length distribution of mutations, number of mutations happened at a given site. Both text and graphical outputs are available. We provide a limited server, a downloadable unlimited server which can be installed locally on any linux/Unix operating system, and a database of mitochondrial gene orders

ParIS Genome Rearrangement server.

SUMMARY: ParIS Genome Rearrangement is a web server for a Bayesian analysis of unichromosomal genome pairs. The underlying model allows inversions, transpositions and inverted transpositions. The server generates a Markov chain using a Partial Importance Sampler technique, and samples trajectories of mutations from this chain. The user can specify several marginalizations to the posterior: the posterior distribution of number of mutations needed to transform one genome into another, length distribution of mutations, number of mutations that have occurred at a given site. Both text and graphical outputs are available. We provide a limited server, a downloadable unlimited server that can be installed locally on any linux/Unix operating system, and a database of mitochondrial gene orders

BIOINFORMATICS APPLICATIONS NOTE Genome analysis ParIS Genome Rearrangement server

Summary: ParIS Genome Rearrangement is a web server for a Bayesian analysis of unichromosomal genome pairs. The underlying model allows inversions, transpositions and inverted transpositions. The server generates a Markov chain using a Partial Importance Sampler technique, and samples trajectories of mutations from this chain. The user can specify several marginalizations to the posterior: the posterior distribution of number of mutations needed to transform one genome into another, length distribution of mutations, number of mutations that have occurred at a given site. Both text and graphical outputs are available. We provide a limited server, a downloadable unlimited server that can be installed locally on any linux/Unix operating system, and a database of mitochondrial gene orders

Attempts on artificial induction of sexual maturation of sterlet (Acipenser ruthenus) and identification of late spermatogenesis stage in hermaphroditic fish

Abstract Most of the 27 species of sturgeons are endangered or close to extinction which is connected to habitat degradation, water pollution and overfishing. Conservation programmes are facing the problem of late maturation which can be reached between 5 and 11 years depending on the species and gender. The aim of our study was to investigate the possibility of shortening the sexual maturation using hormonal administration, and measure the blood serum hormone content to distinguish different genders and maturation stages. There was no effect of a 20-week-long hormonal treatment (10 mg carp pituitary/bodyweight kg/week) on the sexual maturation. The number of females was relatively high (67.6% n = 23) and the number of males was relatively low (11.8%, n = 4). Moreover, the number of hermaphroditic fish was surprisingly high (20.6%, n = 7) and appeared independently from hormone administration. Hermaphroditic fish had fully developed spermatozoa and could be distinguished by the increased level of testosterone hormone in blood serum