65 research outputs found
Metabolism of halophilic archaea
In spite of their common hypersaline environment, halophilic archaea are surprisingly different in their nutritional demands and metabolic pathways. The metabolic diversity of halophilic archaea was investigated at the genomic level through systematic metabolic reconstruction and comparative analysis of four completely sequenced species: Halobacterium salinarum, Haloarcula marismortui, Haloquadratum walsbyi, and the haloalkaliphile Natronomonas pharaonis. The comparative study reveals different sets of enzyme genes amongst halophilic archaea, e.g. in glycerol degradation, pentose metabolism, and folate synthesis. The carefully assessed metabolic data represent a reliable resource for future system biology approaches as it also links to current experimental data on (halo)archaea from the literature
Effect of peptide binding on amide proton exchange rates in the PDZ2 domain from human phosphatase hPTP1E
UI - 99120577NRC publication: Ye
Structural studies of the major glycolipid from Saccharopolyspora genus
NRC publication: Ye
Fusion proteins could generate false positives in peptide phage display
UI - 99111974NRC publication: Ye
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