10 research outputs found

    Prevalensi Karies dan Indeks D E F pada Murid-murid Kelas I, II, dan III Sekolah Dasar yang Berada di Sekitar Klinik Kerja Mahasiswa Fakultas Kedokteran Gigi UNPAD

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    Penelitian ini bertujuan untuk mengetahui gambaran umum tentang statuskesehatan gigi dan mulut pada murid-murid kelas I, II, dan III Sekolah Dasaryang berada di sekitar Klinik Kerja Mahasiswa FKG Unpad dengan melihatprevalensi karies dan indeks def-nya. Jenis penelitian ini adalah deskriptif.Sampel penelitian sebanyak 333 orang murid, yaitu murid-murid kelas I, II, danIII dari 4 buah Sekolah Dasar diambil secara acak, yang berlokasi di sekitar klinikkerja mahasiswa FKG Unpad. Hasil penelitian menunjukkan prevalensi kariesadalah sebesar 99,9% yang berarti hampir semua anak pada penelitian inimenderita karies, sedangkan indeks def adalah 10,2 artinya pada setiap anakyang diperiksa terdapat 10,2 gigi yang mengalami karies, ditambal, dan sudahdicabut atau diindikasikan untuk pencabutan. Hal ini menunjukkan bahwakeadaan kesehatan gigi dan mulut murid-murid kelas I, II, dan III Sekolah Dasaryang berada di sekitar klinik kerja mahasiswa FKG Unpad adalah buruk

    Pharmacological Activity of Chemical Compounds of Potato Peel Waste (Solanum tuberosum L.) in vitro: A Scoping Review

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    Wahyu Hidayat,1,* Irna Sufiawati,1,* Mieke Hemiawati Satari,2,* Ronny Lesmana,3 Solachuddin Ichwan4 1Department of Oral Medicine, Faculty of Dentistry, Universitas Padjadjaran, Bandung, Indonesia; 2Departmen of Oral Biology, Faculty of Medicine, Bandung Islamic University, Bandung, Indonesia; 3Department of Anatomy, Physiology and Biology Cell, Faculty of Medicine, Universitas Padjadjaran, Bandung, Indonesia; 4Dentistry Programme PAPRSB, Institute of Health Sciences, Universiti of Brunei Darussalam, Bandar Seri Bagawan, Brunei Darussalam*These authors contributed equally to this workCorrespondence: Wahyu Hidayat, Email [email protected]: The potato (Solanum tuberosum L.) is a short-lived tuber plant with a round to oval shape and varying colors, depending on the variety. It is known that only the inside of the potato is used, while the peel is generally discarded. However, recent studies have shown that potato peels contain many health-beneficial compounds.Purpose: This study aimed to investigate the compounds present in potato peels and their in vitro activities.Methods: A scoping review following the PRISMA guidelines was conducted. The selection process involved identifying articles of in vitro research published within the last 10 years (2012– 2022). Electronic searches were conducted using the portals Scopus, ScienceDirect, EBSCOhost, and Portal Garuda by using the keywords “potato” or “Solanum tuberosum” and “peel” or “skin”. The search was limited to articles in English with full text availability.Results: The screening process resulted in a total of 4773 articles from the four search engines; 14 articles were obtained that met the requirements for the review, most of which use extract preparations in their research. Extracts of flavonoids, phenols, and glycoalkaloids are the most frequently studied compounds, and their antioxidant and anti-inflammatory activity have undergone extensive research.Conclusion: The potential compounds contained in potato peels, including flavonoids, phenols, and glycoalkaloids, are highly abundant and offer numerous benefits. Provides opportunities for further research to prove the potential pathway activity of the compound. These compounds have been the subject of extensive research, suggesting their significance in the context of health and nutrition.Keywords: flavonoid, peel, antioxidants, anti-inflammator

    The Effects of Potato (Solanum tuberosum L. vs. Granola; Solanaceae) Peel Extract Gel on Gingival Wound Healing in Wistar Rats

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    Faradila Tiarasanti,1,&ast; Irna Sufiawati,1,&ast; Eri Amalia,2 Kartika Indah Sari,3 Cucu Zubaedah,4 Veni Takarini5 1Department of Oral Medicine, Faculty of Dentistry, Padjadjaran University, Bandung, Indonesia; 2Department of Pharmaceutics and Pharmaceutical Technology, Faculty of Pharmacy, Padjadjaran University, Bandung, Indonesia; 3Department of Oral Biology, Faculty of Dentistry, Padjadjaran University, Bandung, Indonesia; 4Department of Dental Public Health, Faculty of Dentistry, Padjadjaran University, Bandung, Indonesia; 5Department of Dental Material Science and Technology, Faculty of Dentistry, Padjadjaran University, Bandung, Indonesia&ast;These authors contributed equally to this workCorrespondence: Irna Sufiawati, Department of Oral Medicine, Faculty of Dentistry, Padjadjaran University, Jalan Sekeloa No. 1, Bandung, West Java, 40132, Indonesia, Tel +62-22-2504985, Email [email protected]: Phenolic compounds with antioxidant, antimicrobial, and anti-inflammatory properties have been identified in potatoes (Solanum tuberosum L.; Solanaceae), which may potentially contribute to wound healing. The study aimed to evaluate the effect of potato peel extract gel Granola variety on oral gingival wound healing in Wistar Rats.Methods: This research was a true experimental in vivo study, involving 30 male Wistar rats, aged 12– 14 weeks and weighing approximately 150 to 200 grams. Surgical vertical incisions, each 3 mm in length, were made on the mandibular gingiva. The test group consisted of six subgroups, each comprising 5 rats. The negative control group received a base gel, while treatment groups were given 1% povidone-iodine solution, 0.1% triamcinolone acetonide oral paste, and 2%, 4%, and 6% potato peel extract gel. Wound lengths were measured on days 3, 7, and 14 to evaluate the healing process. Statistical analysis used the ANOVA test, a p-value of < 0.05 was considered statistically significant.Results: All experimental groups showed a reduction in wound length on days 3, 7, and 14. Notably, the application of 4% and 6% potato peel extract gel formulations facilitated to faster wound healing on day 3, surpassing the povidone-iodine and triamcinolone acetonide groups. However, by days 7 and 14, both the povidone-iodine group and the 6% formulation group demonstrated superior outcomes, although the differences in values were not statistically significant (p < 0.05).Conclusion: Potato peel extract gel formulations at 4% and 6% concentrations were found to expedite the healing of incision wounds, showing no statistically significant difference from the povidone-iodine and triamcinolone acetonide groups. Therefore, potato peel extract gel holds excellent potential for development as an alternative medicine for natural and safe wound healing therapy.Keywords: potato peel extract, gel, wound healin

    Summated Xerostomia Inventory to detect both xerostomia and salivary gland hypofunction

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    OBJECTIVE: This study aims to evaluate the diagnostic performance of the Summated Xerostomia Inventory (SXI-ID) questionnaire in detecting xerostomia and salivary gland hypofunction (SGH). SUBJECTS AND METHODS: This diagnostic study first underwent a validity and reliability test. Participants were randomly sampled from the Geriatric Clinics of Dr. Hasan Sadikin Hospital, Bandung, Indonesia. The SXI-ID was generated through a forward-backward translation, after which its validity (item-total item correlations), internal consistency (Cronbach’s alpha), and test-retest reliability (kappa statistic) were all assessed. The diagnostic performance of the SXI-ID in detecting SGH was evaluated using receiver operating characteristic (ROC) curve analysis. RESULTS: A total of 60 participants (aged ≄60 years) were involved in this study, most of whom were female (75%). The internal consistency of the SXI-ID was acceptable (α = 0.823), and its test-retest reliability was perfect (K= 1.00). ROC analysis showed that an SXI-ID cut-off value > 11 could detect SGH with a sensitivity of 96.0%, a specificity of 100.0%, and an area under the curve of 0.985 (p < 0.001). CONCLUSIONS: The SXI-ID questionnaire is a valid and reliable tool to detect xerostomia and SGH in older Indonesians, and a score of 11 or above is useful to identify those with a low salivary flow

    HIV-1 proteins gp120 and tat induce the epithelial–mesenchymal transition in oral and genital mucosal epithelial cells

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    Release of HIV-1 sequestered in the vesicles of oral and genital mucosal epithelial cells by epithelial-lymphocyte interaction

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