The Emerging Nature of Participation in Multispecies Interaction Design

Interactive technology has become integral part of daily life for both humans and animals, with animals often interacting with technologized environments on behalf of humans. For some, animals' participation in the design process is essential to design technology that can adequately support their activities. For others, animals' inability to understand and control design activities inevitably stands in the way of multispecies participatory practices. Here, we consider the essential elements of participation within interspecies interactions and illustrate its emergence, in spite of contextual constraints and asymmetries. To move beyond anthropomorphic notions of participation, and consequent anthropocentric practices, we propose a broader participatory model based on indexical semiosis, volition and choice; and we highlight dimensions that could define inclusive participatory practices more resilient to the diversity of understandings and goals among part-taking agents, and better able to account for the contribution of diverse, multispecies agents in interaction design and beyond

Developing the control system of a syringe infusion pump

Infusion pumps have multiple uses according to their location. According to its use, there is a need to control specific parameters. The objective of this work is to implement and to assembly all the modules of an infusion pump, controlling all the functions. The control was implemented with the microcontroller board based Arduino and a webpage was developed to assist the user to record, retrieve and access information about the operating conditions.N/

Boundary critical behaviour at mm-axial Lifshitz points: the special transition for the case of a surface plane parallel to the modulation axes

The critical behaviour of $d$-dimensional semi-infinite systems with $n$-component order parameter $\bm{\phi}$ is studied at an $m$-axial bulk Lifshitz point whose wave-vector instability is isotropic in an $m$-dimensional subspace of $\mathbb{R}^d$. Field-theoretic renormalization group methods are utilised to examine the special surface transition in the case where the $m$ potential modulation axes, with $0\leq m\leq d-1$, are parallel to the surface. The resulting scaling laws for the surface critical indices are given. The surface critical exponent $\eta_\|^{\rm sp}$, the surface crossover exponent $\Phi$ and related ones are determined to first order in \epsilon=4+\case{m}{2}-d. Unlike the bulk critical exponents and the surface critical exponents of the ordinary transition, $\Phi$ is $m$-dependent already at first order in $\epsilon$. The \Or(\epsilon) term of $\eta_\|^{\rm sp}$ is found to vanish, which implies that the difference of $\beta_1^{\rm sp}$ and the bulk exponent $\beta$ is of order $\epsilon^2$.Comment: 21 pages, one figure included as eps file, uses IOP style file

Casimir forces in binary liquid mixtures

If two ore more bodies are immersed in a critical fluid critical fluctuations of the order parameter generate long ranged forces between these bodies. Due to the underlying mechanism these forces are close analogues of the well known Casimir forces in electromagnetism. For the special case of a binary liquid mixture near its critical demixing transition confined to a simple parallel plate geometry it is shown that the corresponding critical Casimir forces can be of the same order of magnitude as the dispersion (van der Waals) forces between the plates. In wetting experiments or by direct measurements with an atomic force microscope the resulting modification of the usual dispersion forces in the critical regime should therefore be easily detectable. Analytical estimates for the Casimir amplitudes Delta in d=4-epsilon are compared with corresponding Monte-Carlo results in d=3 and their quantitative effect on the thickness of critical wetting layers and on force measurements is discussed.Comment: 34 pages LaTeX with revtex and epsf style, to appear in Phys. Rev.

Renormalized couplings and scaling correction amplitudes in the N-vector spin models on the sc and the bcc lattices

For the classical N-vector model, with arbitrary N, we have computed through order \beta^{17} the high temperature expansions of the second field derivative of the susceptibility \chi_4(N,\beta) on the simple cubic and on the body centered cubic lattices. (The N-vector model is also known as the O(N) symmetric classical spin Heisenberg model or, in quantum field theory, as the lattice O(N) nonlinear sigma model.) By analyzing the expansion of \chi_4(N,\beta) on the two lattices, and by carefully allowing for the corrections to scaling, we obtain updated estimates of the critical parameters and more accurate tests of the hyperscaling relation d\nu(N) +\gamma(N) -2\Delta_4(N)=0 for a range of values of the spin dimensionality N, including N=0 [the self-avoiding walk model], N=1 [the Ising spin 1/2 model], N=2 [the XY model], N=3 [the classical Heisenberg model]. Using the recently extended series for the susceptibility and for the second correlation moment, we also compute the dimensionless renormalized four point coupling constants and some universal ratios of scaling correction amplitudes in fair agreement with recent renormalization group estimates.Comment: 23 pages, latex, no figure

Improved high-temperature expansion and critical equation of state of three-dimensional Ising-like systems

High-temperature series are computed for a generalized $3d$ Ising model with arbitrary potential. Two specific ``improved'' potentials (suppressing leading scaling corrections) are selected by Monte Carlo computation. Critical exponents are extracted from high-temperature series specialized to improved potentials, achieving high accuracy; our best estimates are: $\gamma=1.2371(4)$, $\nu=0.63002(23)$, $\alpha=0.1099(7)$, $\eta=0.0364(4)$, $\beta=0.32648(18)$. By the same technique, the coefficients of the small-field expansion for the effective potential (Helmholtz free energy) are computed. These results are applied to the construction of parametric representations of the critical equation of state. A systematic approximation scheme, based on a global stationarity condition, is introduced (the lowest-order approximation reproduces the linear parametric model). This scheme is used for an accurate determination of universal ratios of amplitudes. A comparison with other theoretical and experimental determinations of universal quantities is presented.Comment: 65 pages, 1 figure, revtex. New Monte Carlo data by Hasenbusch enabled us to improve the determination of the critical exponents and of the equation of state. The discussion of several topics was improved and the bibliography was update

YangZheng XiaoJi exerts anti-tumour growth effects by antagonising the effects of HGF and its receptor, cMET, in human lung cancer cells

BACKGROUND: Hepatocyte growth factor (HGF) is a cytokine that has a profound effect on cancer cells by stimulating migration and invasion and acting as an angiogenic factor. In lung cancer, the factor also plays a pivotal role and is linked to a poor outcome in patients. In particular, HGF is known to work in combination with EGF on lung cancer cells. In the present study, we investigated the effect of a traditional Chinese medicine reported in cancer therapies, namely YangZheng XiaoJi (YZXJ) on lung cancer and on HGF mediated migration and invasion of lung cancer cells. METHODS: Human lung cancer cells, SKMES1 and A549 were used in the study. An extract from the medicine was used. Cell migration was investigated using the EVOS and by ECIS. Cell–matrix adhesion and in vitro invasion were assessed. In vivo growth of lung cancer was tested using an in vivo xenograft tumour model and activation of the HGF receptor in lung tumours by an immunofluorescence method. RESULTS: Both lung cancer cells increased their migration in response to HGF and responded to YZXJ by reducing their speed of migration. YZXJ markedly reduced the migration and in vitro invasiveness induced by HGF. It worked synergistically with PHA665752 and SU11274, HGF receptor inhibitors on the lung cancer cells both on HGF receptor activation and on cell functions. A combination of HGF and EGF resulted in a greater increase in cell migration, which was similarly inhibited by YZXJ, and in combination with the HGF receptor and EGF receptor inhibitors. In vivo, YZXJ reduced the rate of tumour growth and potentiated the effects of PHA665752 on tumour growth. It was further revealed that YZXJ significantly reduced the degree of phosphorylation of the HGF receptor in lung tumours. CONCLUSION: YZXJ has a significant role in reducing the migration, invasion and in vivo tumour growth of lung cancer and acts to inhibit the migratory and invasive effects induced by HGF and indeed by HGF/EGF. This effect is likely attributed to the inhibition of the HGF receptor activation. These results indicate that YZXJ has a therapeutic role in lung cancer and that combined strategy with methods to block HGF and EGF should be considered. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s12967-015-0639-1) contains supplementary material, which is available to authorized users