PENENTUAN KANDUNGAN TOTAL FLAVONOID DAN TOTAL FENOL DARI AKAR KERSEN (Mutingia calabura) SERTA AKTIVITASNYA SEBAGAI ANTIOKSIDAN

Penelitian ini bertujuan untuk mengetahui kadar fenol dan flavonoid total dari ekstrak akar kersen serta aktivitas antioksidannya. Hasil ekstraksi 1 kg akar kersen menghasilkan ekstrak etanol (30,56 g), kloroform (6,52 g), etilasetat (6,1 g), n-butanol (3,21 g) dan air (4,65 g). Penapisan fitokimia menunjukkan ekstrak yang positif flavonoid adalah ekstrak air, kloroform, etanol dan etil asetatsedangkankelimaekstrak tersebut positif mengandung polifenol.  Ekstrak etanol, n-butanol, kloroform, etil asetat, dan air memiliki kandungan total fenol berturut-turut yaitu 12,62%, 3,81%, 6,12%, 8,75%, dan 11,93%. Kandungan flavonoid pada ekstrak etanol, kloroform, etil asetat, dan air berturut-turut yaitu 0,22%, 0,05%, 0,12%, dan 0,03%. Aktivitas antioksidan pada ekstrak etanol diukur dengan metode DPPH dan dinyatakan dengan nilai IC50 sebesar 36,44 pp

PROVISION OF CINNAMON BARK ETHANOL EXTRACT (Cinnamomum burmanii Blume) LOWER BLOOD SUGAR LEVELS HYPERGLYCEMIC WISTAR RATS

Cinnamon plant (Cinnamomum burmanii Blume) is a tall plant that contains secondary metabolites and is widely consumed by the community for generations which is used as a medicinal ingredient. The part of the cinnamon plant that is widely used by the community is the bark. Cinnamon bark extraction was carried out by maceration method in 96% ethanol followed by evaporation until a thick extract was formed. Furthermore, characterization was carried out and applied to hyperglycemic wistar rats by observing the decrease in blood sugar levels. The results showed that the moisture content was 9.62% and the yield was 14.74% and the phytochemical test showed that the cinnamon bark extract was positive for polyphenols and flavonoids. Cinnamon bark extract was able to reduce blood sugar levels of hyperglycemic wistar rats to reach normal which was observed from the third day after being injected with alloxan until the seventeenth day