5 research outputs found
Why Are tRNAs Overproduced in the Absence of Maf1, a Negative Regulator of RNAP III, Not Fully Functional?
No full textActive Center Control of Termination by RNA Polymerase III and tRNA Gene Transcription Levels In Vivo
No full textSub1 and Maf1, Two Effectors of RNA Polymerase III, Are Involved in the Yeast Quiescence Cycle
No full textAltered nuclear tRNA metabolism in La-deleted Schizosaccharomyces pombe is accompanied by a nutritional stress response involving Atf1p and Pcr1p that is suppressible by Xpo-t/Los1p
Get PDFThe La protein controls pre-tRNA metabolism in nuclei. Deletion of Schizosaccharomyces pombe La leads to altered pre-tRNA metabolism and up-regulation of amino acid genes and nutrient-sensitive growth defects, accompanied by apparently inefficient tRNA nuclear export. These sla1-Δ phenotypes are suppressed by modest overexpression of the tRNA nuclear export factor Los1p
