9 research outputs found
Antihypertensive effect of a fixed-dose combination of losartan /hydrochlorothiazide in patients with uncontrolled hypertension: a multicenter study
Get PDFRenin- angiotensin system in control of vascular reactivity
No full textThis paper aimed to present recent knowledge of the role of the renin-angiotensin system (RAS) in the control of vascular relaxation mechanisms and the relation to development and maintenance of hypertension. The emphasisis given on the role of oxidative stress and NO ā dependent and prostanoid - dependent vascular relaxation mechanisms that are impaired in SS salt-sensitive rat strain (that exhibit chronically low plasma renin activity), and restored in consomic SS.13BN rats (that have chromosome 13, containing renin gene, introgressed from BN rat into SS genetic background). In conclusion, results of numerous experimental studies suggest that hypoactive (as well as hyperactive) RAS may contribute to development and maintenance of hypertension due to the effects of angiotensin II on vascular reactivity
Prevalence and Associated Factors of Prehypertension and Hypertension in Iranian Population: The Lifestyle Promotion Project (LPP)
No full textDysregulation of microRNAs and renin-angiotensin system in high salt diet-induced cardiac dysfunction in uninephrectomized rats
No full textExcessive salt consumption causes systemic calcium mishandling and worsens microarchitecture and strength of long bones in rats
No full textSalicornia: evaluating the halophytic extremophile as a food and a pharmaceutical candidate
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