Magnetic susceptibility of the QCD vacuum at finite quark-chemical potential

We investigate the QCD magnetic susceptibility chi at the finite quark-chemical potential (mu>0) and at zero temperature (T=0) to explore the pattern of the magnetic phase transition of the QCD vacuum. For this purpose, we employ the nonlocal chiral quark model derived from the instanton vacuum in the presence of the chemical potential in the chiral limit. Focusing on the Nambu-Goldstone phase, we find that the magnetic susceptibility remains almost stable to mu~200 MeV, and falls down drastically until the the quark-chemical potential reaches the critical point mu_c~320 MeV. Then, the strength of the chi is reduced to be about a half of that at mu=0, and the first-order magnetic phase transition takes place, corresponding to the chiral restoration. From these observations, we conclude that the response of the QCD vacuum becomes weak and unstable to the external electromagnetic field near the critical point, in comparison to that for vacuum. It is also shown that the breakdown of Lorentz invariance for the magnetic susceptibility, caused by the finite chemical potential, turns out to be small.Comment: 12 pages, 2 figure

Marginal deterrence in the enforcement of law: Evidence from distributed denial of service attack

Best Faculty Research Paper Award</p

Linear programming method to construct equated item sets for the implementation of periodical computer-based testing for the Korean Medical Licensing Examination

Purpose This study aimed to identify the best way of developing equivalent item sets and to propose a stable and effective management plan for periodical licensing examinations. Methods Five pre-equated item sets were developed based on the predicted correct answer rate of each item using linear programming. These pre-equated item sets were compared to the ones that were developed with a random item selection method based on the actual correct answer rate (ACAR) and difficulty from item response theory (IRT). The results with and without common items were also compared in the same way. ACAR and the IRT difficulty were used to determine whether there was a significant difference between the pre-equating conditions. Results There was a statistically significant difference in IRT difficulty among the results from different pre-equated conditions. The predicted correct answer rate was divided using 2 or 3 difficulty categories, and the ACAR and IRT difficulty parameters of the 5 item sets were equally constructed. Comparing the item set conditions with and without common items, including common items did not make a significant contribution to the equating of the 5 item sets. Conclusion This study suggested that the linear programming method is applicable to construct equated-item sets that reflect each content area. The suggested best method to construct equated item sets is to divide the predicted correct answer rate using 2 or 3 difficulty categories, regardless of common items. If pre-equated item sets are required to construct a test based on the actual data, several methods should be considered by simulation studies to determine which is optimal before administering a real test

Potential effectiveness of digital therapeutics specialized in executive functions as adjunctive treatment for clinical symptoms of attention-deficit/hyperactivity disorder: a feasibility study

IntroductionThe role of digital therapeutics (DTx) in the effective management of attention deficit/hyperactivity disorder (ADHD) is beginning to gain clinical attention. Therefore, it is essential to verify their potential efficacy.MethodWe aimed to investigate the improvement in the clinical symptoms of ADHD by using DTx AimDT01 (NUROW) (AIMMED Co., Ltd., Seoul, Korea) specialized in executive functions. NUROW, which consists of Go/No-go Task- and N-Back/Updating-based training modules and a personalized adaptive algorithm system that adjusts the difficulty level according to the user’s performance, was implemented on 30 Korean children with ADHD aged 6 to 12 years. The children were instructed to use the DTx for 15 min daily for 4 weeks. The Comprehensive attention test (CAT) and Childhood Behavior Checklist (CBCL) were used to assess the children at baseline and endpoint. In contrast, the ADHD-Rating Scale (ARS) and PsyToolkit were used weekly and followed up at 1 month, for any sustained effect. Repeated measures ANOVA was used to identify differences between the participants during visits, while t-tests and Wilcoxon signed-rank tests were used to identify changes before and after the DTx.ResultsWe included 27 participants with ADHD in this analysis. The ARS inattention (F = 4.080, p = 0.010), hyperactivity (F = 5.998. p &lt; 0.001), and sum (F = 5.902, p &lt; 0.001) significantly improved. After applying NUROW, internalized (t = −3.557, p = 0.001, 95% CI = −3.682-−0.985), other (Z = −3.434, p = 0.001, effect size = −0.661), and sum scores (t = −3.081, p = 0.005, 95% CI = −10.126-−2.022) were significantly changed in the CBCL. The overall effect was confirmed in the ARS sustained effect analysis even after 1 month of discontinuing the DTx intervention.DiscussionAccording to caregivers, the findings indicate that DTx holds potential effect as an adjunctive treatment in children with ADHD, especially in subjective clinical symptoms. Future studies will require detailed development and application targeting specific clinical domains using DTx with sufficient sample sizes.Clinical trial registration: KCT0007579