3,372 research outputs found

    Simple Syllable Structure and English Pre-nucleus Glides

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    Dual-Counting Feet in English

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    The syllabic trochee is assumed for English. However, all syllable-counting theories require devices to consult moraic information, guaranteeing the at heavy syllables receive stress. Furthermore, given the standard assumption that a minimal word is a foot, syllable counting theories predict that the minimal word in English is disyllabic. However, this disyllabic minimal word requirement is plainly inadequate. On the other hand, mora-counting is not sufficient, either; Hayes'(1995: 123) moraic trochee theory must refer to syllables in order to guarantee that moras belonging to a single syllable cannot be separated into two different feet, i.e., to preserve syllable integrity. Moreover, extrametricality is defined in terms of syllables rather than moras. These suggest, then, that English needs both moraic and syllabic levels. Consequently, I propose to make both moras and syllables represented in the phonological representations for English

    Intra-abdominal Esophageal Duplication Cyst in an Adult

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    Esophageal duplication cysts are congenital anomalies of the foregut that are rarely found in the abdomen. An accurate preoperative diagnosis is not always possible, so the definitive diagnosis can be made by histologic examination of the surgical specimen. We experienced a case of Intra-abdominal esophageal duplication cyst in a 52-year-old female, who initially presented with an esophageal submucosal tumor on upper gastrointestinal endoscopy. She did not have any gastrointestinal symptoms. Barium esophagography, chest computed tomography scan and endoscopic ultrasonography demonstrated the cystic lesion in the intra-abdominal esophagus. Transhiatal enucleation of the lesion was performed successfully via the abdominal approach with no postoperative complications. Histologic study showed that the cyst wall contained a two-layered muscle coat and the surface of the lumen was lined by pseudo-ciliated columnar epithelium. The patient has been doing well without any complaints for 3 months of follow-up period

    Usefulness of Allerkin House Dust Mite Extract for Nasal Provocation Testing

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    Objectives We evaluated the clinical usefulness of Allerkin (Lofarma) for nasal provocation testing (NPT) in patients with rhinitis symptoms, by examining changes in nasal symptoms and acoustic parameters after exposure to house dust mite (HDM) extract. Methods Twenty patients (16 males and 4 females, mean age: 29.6±14.6 years) were enrolled. We performed skin prick test (SPT) before and 15 and 30 minutes after intranasal challenge with Allerkin HDM extract, and we evaluated symptom changes (nasal obstruction, rhinorrhea, sneezing, and itching) using a visual analogue scale. We also evaluated changes in acoustic parameters such as total nasal volume (TNV) and minimal cross-sectional area (MCA) before and after challenge. Results Group A (the nonallergic group, n=8) showed negative results for all tested aeroallergens in SPT and nonprovocative results (29% decrease in TNV/MCA from the baseline value). Patients in group C showed significant aggravation of nasal obstruction compared to those in group A (P<0.05). Thirty minutes after HDM challenge, patients in groups B and C showed significantly greater decreases in MCA compared to those in group A (P<0.01). Conclusion Allerkin HDM extract can be a useful provocative agent in NPT for diagnosing allergic rhinitis and local allergic rhinitis

    Anti-allergic effect of luteolin in mice with allergic asthma and rhinitis

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    Abstract Aim of the study : Results: after the oVa challenge, the number of eosinophils, neutrophils and lymphocytes in BaL fluid was significantly increased in group B, compared to group a (p &lt; 0.001). mice in group C had no significant difference (p &gt; 0.05). on the other hand, group D showed a significant decrease in all inflammatory cells compared to group B (p &lt; 0.05). also, group D showed a significant decrease in iL-4, iL-5 and iL-13 in their lung homogenate compared to groups B and C (p &lt; 0.05). group D also showed a significant decrease in inflammatory cell infiltration after luteolin treatment (p &lt; 0.05). Conclusion: Luteolin had an anti-allergic effect in a murine model of allergic asthma and rhinitis

    FESD: a Functional Element SNPs Database in human

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    We have created the Functional Element SNPs Database (FESD) that categorizes functional elements in human genic regions and provides a set of single nucleotide polymorphisms (SNPs) located within each area. In the FESD, the human genic regions were divided into 10 different functional elements, such as promoter regions, CpG islands, 5′-untranslated regions (5′-UTRs), translation start sites, splice sites, coding exons, introns, translation stop sites, polyadenylation signals and 3′-UTRs, and subsequently, all the known SNPs were assigned to each functional element at their respective position. With the FESD web interface, users can select a set of SNPs in the specific functional elements and get their flanking sequences for genotyping experiments, which will help in finding mutations that contribute to the common and polygenic diseases. A web interface for the FESD is freely available at http://combio.kribb.re.kr/ksnp/resd/
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