345 research outputs found

    Do I Know My Body Size? An Examination of College Students Involved in Fashion

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    Female college students often show their interests in fashion by volunteering to be a model for a senior fashion show. Also, their preferences of a certain clothing style reflect or be reflective of their fashion involvement. This raised following questions: What are the actual and perceived body sizes of the college students wanting to be a fashion model? Do they have any distinctive body image perception? Do they have a better understanding of their weight status and sizes? Thus, this study aims 1) to understand how college students involved in fashion perceive their body images and 2) to assess their body image discrepancies between the actual body sizes and perceived sizes

    The Perception of Colors in Fashion: A Cohort Comparison of Baby Boomers and Generation Y

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    Colors of clothing affect psychology of consumers and the psychological effects and meaning of colors may vary by generation and culture. Thus, the purpose of this study is to investigate if baby boomers and generation Y have different interpretation of colors, and how their color perceptions are related to self-esteem, social motivation for fashion consumption and fashion involvement. A quasi-experimental quantitative survey method was used for this study. Respondents consisted of two generations including 50 baby boomers in age 65 or older and 50 generation Y individuals. Results showed that baby boomers, generally, prefer bright colors such as orange whereas generation Y prefers dark colors such as black. Also, self-esteem and fashion involvement are important factors of understanding their different color perceptions. The results from this study can be useful for apparel manufacturers and retailers to understand each generation\u27s different perceptions of clothing color

    Clothing Selection Motivations and Challenges for Individuals with Alzheimer’s Disease: A Qualitative Exploration of Caregivers’ Viewpoints

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    The study explored current adaptive clothing items that are available for individuals with Alzheimer’s and explore their needs of effective clothing features from their caregiver’s viewpoints

    A Case Study of the 3D Design Process Applied for Customized Art Wears

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    This study was aimed to examine the efficiency of using 3D virtual design tools for customization process and creative design process by creating art wears with 3D design tools for individuals. The 3D Design for Art Wear Project has been conducted by collaborating in creating a wearable form from a digital print in art. For the project, art wears were designed with OptiTex 3D virtual design tool and 3D body scanner to create a seamless art wear from a genuine digital print art Superficial Outgrowth created by the artist. A customized wearable art with 3D design has been developed in this project. It is a remarkable that once a person has been scanned with a 3D body scanner, stored in the 3D system and designed in 3D, mapping the art without unnecessary cutting and no physical fitting process

    A Sizing System for Big & Tall: Comparison between Proportional Sizing System and Linear Regression Model Approach

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    This study aimed to identify applicable sizing systems for big and tall men by examining current menswear sizing systems. A cluster analysis, a linear regression, and t-test with fit comparison plots were employed to test two dominant approaches of sizing systems: 1) a size chart based on proportions of a sampling distribution of means in normal distribution, which is the most common approach of sizing in the apparel industry; and 2) a size chart developed with a liner regression model. Body dimensions from a total of 301 big and tall men height over 71.5 inches and weight over 215 pounds were tested with the two size charts. Similar characteristics of big and tall were identified with the cluster analysis. While the sizing system with proportion displayed more deviations, the sizing system with a liner regression model predicted more of actual big and tall men’s body dimensions

    Crystal structure of Cmr5 from Pyrococcus furiosus and its functional implications

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    AbstractThe bacterial acquired immune system consists of clustered regularly interspaced short palindromic repeats (CRISPRs) and CRIPSR-associated (Cas) genes, which include Cas-module repeat-associated mysterious proteins (Cmr). The six Cmr proteins of Pyrococcus furiosus (pfCmr1–pfCmr6) form a Cmr effector complex that functions against exogenous nucleic acid. Among the Cmr proteins, the role of pfCmr5 and its involvement in the complex’s cleavage activity have been obscure. The elucidated pfCmr5 structure has two inserted α-helices compared with the other trimeric Cmr5 structure. However, pfCmr5 exists as a monomeric protein both in the crystalline state and in solution. In vitro assays indicate that pfCmr5 interacts with pfCmr4. These structural and biophysical data might help in understanding the complicated and ill-characterized Cmr effector complex.Structured summary of protein interactionspfCmr4 and pfCmr5 bind by molecular sieving (View interaction)pfCmr4 and pfCmr4 bind by molecular sieving (View interaction)pfCmr5 and pfCmr4 bind by ion exchange chromatography (View interaction

    Cytomegalovirus-associated esophageal ulcer in an immunocompetent infant: When should ganciclovir be administered?

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    Cytomegalovirus (CMV)-associated esophageal ulcer is rare in immunocompetent infants. The presence of inclusion bodies and immunohistochemical staining for CMV in biopsy specimens obtained during esophagogastroduodenoscopy (EGD) indicate that such ulcers occur because of CMV infection. A 7-week-old female infant who experienced frequent vomiting and feeding intolerance was diagnosed with a massive CMV-associated ulcer in the distal esophagus. The ulcer improved after conservative treatment using proton-pump inhibitors; however, ganciclovir was not administered. In a follow-up EGD biopsy specimen, no CMV inclusion bodies were present, and immunohistochemical staining results for this virus were negative. The presence of CMV inclusion bodies indicates active viral replication. If persistent inclusion bodies or positive immunohistochemical staining for CMV is observed in follow-up biopsy specimens, ganciclovir may be used to treat CMV-associated esophageal ulcers

    Risk factors associated with death due to severe fever with thrombocytopenia syndrome in hospitalized Korean patients (2018–2022)

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    Objectives Severe fever with thrombocytopenia syndrome (SFTS) has no vaccine or treatment and an extremely high fatality rate. We aimed to analyze and evaluate the risk factors for death associated with SFTS. Methods Among reports from 2018 to 2022, we compared and analyzed 1,034 inpatients aged 18 years or older with laboratory-confirmed SFTS who underwent complete epidemiological investigations. Results Most of the inpatients with SFTS were aged 50 years or older (average age, 67.6 years). The median time from symptom onset to death was 9 days, and the average case fatality rate was 18.5%. Risk factors for death included age of 70 years or older (odds ratio [OR], 4.82); agriculture-related occupation (OR, 2.01); underlying disease (OR, 7.20); delayed diagnosis (OR, 1.28 per day); decreased level of consciousness (OR, 5.53); fever/chills (OR, 20.52); prolonged activated partial thromboplastin time (OR, 4.19); and elevated levels of aspartate aminotransferase (OR, 2.91), blood urea nitrogen (OR, 2.62), and creatine (OR, 3.21). Conclusion The risk factors for death in patients with SFTS were old age; agriculture-related occupation; underlying disease; delayed clinical suspicion; fever/chills; decreased level of consciousness; and elevated activated partial thromboplastin time, aspartate aminotransferase, blood urea nitrogen, and creatine levels

    Effects of Berberine and Hwangryunhaedok-Tang on Oral Bioavailability and Pharmacokinetics of Ciprofloxacin in Rats

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    Hwangryunhaedok-Tang (HR) and berberine-containing single herbs are used to treat bacterial infection and inflammatory diseases in eastern Asia. The combination of berberine-containing herbal medicines and ciprofloxacin can be an excellent antibacterial chemotherapy against multidrug resistance bacteria. To evaluate the pretreatment effect of berberine and HR, vehicle, berberine (25 and 50 mg/kg/day), and HR (1.4 g/kg/day) were daily administered to rats for five consecutive days. On day 6, ciprofloxacin was administered (10 mg/kg, i.v. and 20 mg/kg, p.o.) to rats. To assess cotreatment effect of berberine and ciprofloxacin, berberine (50 mg/kg) and ciprofloxacin (20 mg/kg) were coadministered by single oral gavage. Pharmacokinetic data were estimated by noncompartmental model. Compared with ciprofloxacin alone (control group), coadministration of berberine (50 mg/kg) and ciprofloxacin significantly decreased Cmax of ciprofloxacin (P<0.05). In addition, the pretreatment of berberine (50 mg/kg/day) and HR (1.4 g/kg/day) significantly decreased Cmax and AUC0→∞, compared with control group (P<0.05). The oral bioavailability of ciprofloxacin was reduced by cotreatment of berberine and pretreatment of berberine and HR. Our results suggest that the expression of P-glycoprotein and organic anion and/or organic cation transporters (OAT/OCT) could take a role in reduced oral bioavailability of ciprofloxacin by berberine and HR
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