kt Effects in Direct-Photon Production

We discuss the phenomenology of initial-state parton-kt broadening in direct-photon production and related processes in hadron collisions. After a brief summary of the theoretical basis for a Gaussian-smearing approach, we present a systematic study of recent results on fixed-target and collider direct-photon production, using complementary data on diphoton and pion production to provide empirical guidance on the required amount of kt broadening. This approach provides a consistent description of the observed pattern of deviation of next-to-leading order QCD calculations relative to the direct-photon data, and accounts for the shape and normalization difference between fixed-order perturbative calculations and the data. We also discuss the uncertainties in this phenomenological approach, the implications of these results on the extraction of the gluon distribution of the nucleon, and the comparison of our findings to recent related work.Comment: LaTeX, uses revtex and epsf, 37 pages, 15 figure

A simplified structure for the second order cosmological perturbation equations

Increasingly accurate observations of the cosmic microwave background and the large scale distribution of galaxies necessitate the study of nonlinear perturbations of Friedmann-Lemaitre cosmologies, whose equations are notoriously complicated. In this paper we present a new derivation of the governing equations for second order perturbations within the framework of the metric-based approach that is minimal, as regards amount of calculation and length of expressions, and flexible, as regards choice of gauge and stress-energy tensor. Because of their generality and the simplicity of their structure our equations provide a convenient starting point for determining the behaviour of nonlinear perturbations of FL cosmologies with any given stress-energy content, using either the Poisson gauge or the uniform curvature gauge.Comment: 30 pages, no figures. Changed title to the one in published version and some minor changes and addition

A Field Range Bound for General Single-Field Inflation

We explore the consequences of a detection of primordial tensor fluctuations for general single-field models of inflation. Using the effective theory of inflation, we propose a generalization of the Lyth bound. Our bound applies to all single-field models with two-derivative kinetic terms for the scalar fluctuations and is always stronger than the corresponding bound for slow-roll models. This shows that non-trivial dynamics can't evade the Lyth bound. We also present a weaker, but completely universal bound that holds whenever the Null Energy Condition (NEC) is satisfied at horizon crossing.Comment: 16 page

Targeting the master regulator mTOR: A new approach to prevent the neurological of consequences of parasitic infections?

© 2017 The Author(s). A systematic analysis of 240 causes of death in 2013 revealed that parasitic diseases were responsible for more than one million deaths. The vast majority of these fatalities resulted from protozoan infections presenting with neurological sequelae. In the absence of a vaccine, development of effective therapies is essential to improving global public health. In 2015, an intriguing strategy to prevent cerebral malaria was proposed by Gordon et al. 2015 mBio, 6:e00625. Their study suggested that inhibition of the mammalian target of rapamycin prevented experimental cerebral malaria by blocking the damage to the blood brain barrier and stopping the accumulation of parasitized red blood cells and T cells in the brain. Here, we hypothesize that the same therapeutic strategy could be adopted for other protozoan infections with a brain tropism, to prevent cerebral parasitosis by limiting pathogen replication and preventing immune mediated destruction of brain tissue

Heavy Quark Mass Effects in Deep Inelastic Scattering and Global QCD Analysis

A new implementation of the general PQCD formalism of Collins, including heavy quark mass effects, is described. Important features that contribute to the accuracy and efficiency of the calculation of both neutral current (NC) and charged current (CC) processess are explicitly discussed. This new implementation is applied to the global analysis of the full HERA I data sets on NC and CC cross sections, with correlated systematic errors, in conjunction with the usual fixed-target and hadron collider data sets. By using a variety of parametrizations to explore the parton parameter space, robust new parton distribution function (PDF) sets (CTEQ6.5) are obtained. The new quark distributions are consistently higher in the region x ~ 10^{-3} than previous ones, with important implications on hadron collider phenomenology, especially at the LHC. The uncertainties of the parton distributions are reassessed and are compared to the previous ones. A new set of CTEQ6.5 eigenvector PDFs that encapsulates these uncertainties is also presented.Comment: 32 pages, 12 figures; updated, Publication Versio

Examination of direct-photon and pion production in proton-nucleon collisions

We present a study of inclusive direct-photon and pion production in hadronic interactions, focusing on a comparison of the ratio of gamma/pi0 yields with expectations from next-to-leading order perturbative QCD (NLO pQCD). We also examine the impact of a phenomenological model involving k_T smearing (which approximates effects of additional soft-gluon emission) on absolute predictions for photon and pion production and their ratio.Comment: 20 pages, 12 figures. Minor changes in wording and in figure

Homozygous knockout of the piezo1 gene in the zebrafish is not associated with anemia

We have now examined the erythroid phenotype in this zebrafish strain carrying a ZFN genomic knockout of piezo1. Genotyping was performed as previously described. In contrast to the anemic phenotype observed in zebrafish subjected to morpholino knockdown of piezo, the genomic ZFN knockout of piezo1 did not segregate either with anemia in the 3-dpf embryo or with dysmorphic erythrocyte morphology in the adult fish

A New Scintillator Tile/Fiber Preshower Detector for the CDF Central Calorimeter

A detector designed to measure early particle showers has been installed in front of the central CDF calorimeter at the Tevatron. This new preshower detector is based on scintillator tiles coupled to wavelength-shifting fibers read out by multi-anode photomultipliers and has a total of 3,072 readout channels. The replacement of the old gas detector was required due to an expected increase in instantaneous luminosity of the Tevatron collider in the next few years. Calorimeter coverage, jet energy resolution, and electron and photon identification are among the expected improvements. The final detector design, together with the R&D studies that led to the choice of scintillator and fiber, mechanical assembly, and quality control are presented. The detector was installed in the fall 2004 Tevatron shutdown and started collecting colliding beam data by the end of the same year. First measurements indicate a light yield of 12 photoelectrons/MIP, a more than two-fold increase over the design goals.Comment: 5 pages, 10 figures (changes are minor; this is the final version published in IEEE-Trans.Nucl.Sci.

Prompt photons at RHIC

We calculate the inclusive cross section for prompt photon production in heavy-ion collisions at RHIC energies ($\sqrt{s}=130$ GeV and $\sqrt{s}=200$ GeV) in the central rapidity region including next-to-leading order, $O(\alpha_{em}\alpha_s^2)$, radiative corrections, initial state nuclear shadowing and parton energy loss effects. We show that there is a significant suppression of the nuclear cross section, up to $\sim 30$ at $\sqrt{s}=200$ GeV, due to shadowing and medium induced parton energy loss effects. We find that the next-to-leading order contributions are large and have a strong $p_t$ dependence.Comment: 9 pages, 5 figures, expanded discussion of the K facto

High Q^2 Deep Inelastic Scattering at HERA

High Q^2 NC and CC cross-sections as measured at HERA can give information on two distinct areas of current interest. Firstly, supposing that all the electroweak parameters are well known, these cross-sections may be used to give information on parton distributions at high x and high Q^2. Secondly, supposing that parton distributions are well known, after evolution in Q^2 from the kinematic regime where they are already measured, these cross-sections can be used to give information on electroweak parameters in a process where the exchanged boson is `spacelike' rather than `timelike'. WG1 addressed itself to clarifying the limits of our present and possible future knowledge on both these areas.Comment: 26 pages, 12 figures. Uses iopart.cls, iopart12.clo, axodraw.sty. Report of WG1 of the 3rd UK Phenomenology Workshop on HERA Physics, Durham 1998. To be published in Journal of Physics