9,539 research outputs found
Effect of material properties on ductility of reinforced concrete beams
Reinforced concrete (RC) is one of the most important building materials and is widely used in civil engineering structures. The constituents of reinforced concrete such as concrete and steel are very complex due to their different mechanical properties. The stress-strain behavior of concrete under short term compression loading is considered parabolic and that of the steel is elastic plastic. Concrete and reinforcing steel are represented by separate material models that are combined together to describe the behavior of the RC beam sections. The end displacements of the steel element are assumed to be compatible with the boundary displacements of the concrete element which implied perfect bond between them. This paper presents the effects of materials properties such as concrete compressive strength, yield strength of steel and reinforcement content on the curvature ductility of singly reinforced concrete beams as well as doubly reinforced concrete beams. From the analyses, it is observed that the ductility of a singly RC beam decreases as the tension steel content is increased, and the presence of compression steel increases the ductility significantly. For the same reinforcement content the increase in compressive strength of concrete increases curvature ductility of reinforced concrete section and for a doubly reinforced section rate of increase of curvature is more than that of a singly reinforced section. However, the moment ratio increases at a relatively slow rate than that of singly reinforced beams. On the other hand the ductility of RC beams decreases as the strength of reinforcement is increased
Innovation in engineering consultancy: a case for competitive advantage
The internationalisation of the engineering consultancy services brings new challenges to its competitiveness. Service innovation is the way to enhance competitiveness. Although competitive innovation in the 1990s was achieved by information and communication technologies adoption, it is no longer sustainable without the combination of entrepreneurship, learning, sharing, knowledge and creativity, and by using information and communication technologies as a tool. The firm and the individual face challenges from external perceptions, internal beliefs, institutional legacies and organisation cultural misalignments. This paper proposes a knowledge-based model for re-engineering the firm with a learning culture. If engineering consultancy is a knowledge-based business whose asset is the employees, then the firm has to manage knowledge in an organisational learning and sharing context for the innovation purpose. Knowledge management with a human resource strategy for learning is a means to leverage the know-how, experience and judgment of the pool of highly qualified labour to achieve the innovation objective by replacing irrelevant work routines with dynamic ones
Stakeholders assessment of constraints to project delivery in the Nigerian construction industry
The central goal of construction stakeholders is to successfully deliver projects to stated
objective (s). However, for decades, construction projects have been plagued by perennial
constraints of cost and time overruns, poor quality, and lack of sustainability. The objective of
this paper is to identify and assess the constraints to construction project delivery, and to
recommend solutions to enhance project performance. This paper adopted both quantitative
and qualitative methods to establish the constraints in the Nigerian construction industry. A
pilot survey and literature reviewed revealed a total of fifty (50) construction constraints,
which were further classified into eight (8) major groups. Well-structured questionnaires were
administered to construction stakeholders (client, consultant and contractor) in Abuja, the
federal capital city of Nigeria. Relative Importance Index (RII) was used to analyze the data
using Likert scale. The results suggest that cost/time overrun related factors (inability to
reduce project cost), Stakeholders interactive-related factors (inability to establish client value
system), Client-related factors (Delay in interim payment and finance problem), and Labor/
material-related factors (escalation of material prices and materials quality variability) are the
most prevalent constraints in the Nigerian construction environment. To mitigate the effects
of these challenges, it is suggested that a formal innovative approach should be used by
stakeholders to address the problems of poor communication, high project cost, and delay.
Clients should also take measures to provide adequate funding and should promptly honor
interim certificates
Endovascular Aneurysm Repair (EVAR) for infra-renal Abdominal Aortic Aneurysm (AAA) under local anaesthesia - initial experience in Hospital Kuala Lumpur
This is our initial report on the first 4 cases of infra-renal abdominal aortic aneurysms undergoing Endovascular Aneurysm Repair (EVAR) with local anaesthesia, controlled sedation and monitoring by an anaesthetist. All 4 patients were males with a mean age of 66.7 years. Only one (1) required ICU stay of 2 days for cardiac monitoring due to bradycardia and transient hypotension post procedure. No mortality or major post operative morbidity was recorded and the mean hospital stay post procedure was 3.5 days (range 2-5 days)
Retention of knowledge following training of students in basic trauma life support
Introduction: In the course of their undergraduate training at
the International Medical University, students receive a
Basic Trauma Life Support course.
Objective: We wanted to test the long-term retention of
knowledge (after 16 months) of third year medical students
who had received training in Basic Trauma Life Support
Method: To assess the retention of knowledge one cohort of
students who received the training course were tested again
16 months later using the same 30 question One Best
Answer quiz.
Results: Seventy-three students who underwent the course
sat for the Retention test. The number of students who
passed the Retention test was not significantly different
from the test taken immediately after the course. The mean
scores, 62.5% and 59.5% respectively, were however
significantly different.
Conclusion: Our study involves a relatively long interval
between the course and retention of knowledge test shows
encouraging results
Adherence of Streptococcus pneumoniae and expression analysis of neuraminidase gene (NanA and NanB) after interaction of A549 human lung epithelial cells with pneumococcal strains of various serotypes
Aims: Streptococcus pneumoniae is the most common bacterial respiratory pathogen that can lead to invasive diseases
such as pneumonia, bacteremia, and meningitis. The interaction of S. pneumoniae with host respiratory epithelial cells is
crucial in the colonization of human respiratory tract and involve in the virulence. The aim of the study is to investigate
the adherence of S. pneumoniae and the effect of serotypic variation on neuraminidase genes (NanA and NanB) after
interaction of A549 human lung epithelial cells with S. pneumoniae serotypes.
Methodology and results: Six different serotypes of S. pneumoniae were used (1, 3, 5, 19F, 23F, and 14). A549
human lung epithelial cells were inoculated with pneumococcal strains of different serotype for 3 hours. The number of
adherent bacteria was determined by serial dilution followed by spread plate technique on tryptic soy agar supplemented
with 5% sheep blood. Bacterial RNA was harvested from the infected A549 cells. The differential expression level of
neuraminidases was observed by quantitative real-time PCR (qRT-PCR). Based on bacterial adherence assay, serotype
14 showed highest adherence, meanwhile, serotype 23F showed lowest adherence. This suggests that serotype 14 has
a better affinity to adhere to A549 cells as compared to serotype 23F. Higher NanA gene expression was observed in
serotype 5, 23F and 19F, while lower expression in serotype 14. In contrast, NanB gene shows low-level expression in
serotype 23F and 19F, while higher expression in serotype 14. This postulates that NanA and NanB gene may have
different functions in the pathogenesis of S. pneumoniae.
Conclusion, significance and impact of study: Our finding on differential expression of neuraminidase gene of S.
pneumoniae of various serotypes on A549 cells might give a better understanding of host pathogen interaction between
bacteria serotypes and host cell
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