Application of a new choline-imidazole based deep eutectic solvents in hybrid magnetic molecularly imprinted polymer for efficient and selective removal of naproxen from aqueous samples

A magnetic molecularly imprinted polymer (Fe3O4@MIP) with naproxen (as template) was successfully prepared by adding a co-solvent consisting of a choline-imidazole based deep eutectic solvent (ChCl-BuIM) during polymerisation. The morphological, functional group, and magnetic characteristics of the synthesised materials were characterised by elemental analysis, Fourier transform-infrared spectroscopy, scanning electron microscopy, and vibrating sample magnetometer. This hybrid Fe3O4@MIP-ChCl-BuIM material was used as a magnetic adsorbent for efficient and selective removal of naproxen from wastewater samples. A batch adsorption study showed that adsorption of naproxen onto the multilayer surface of the adsorbent through a chemisorption mechanism. The data showed that the adsorption was feasible, spontaneous, and exothermic. The Fe3O4@MIP-ChCl-BuIM removed more naproxen (93.2–97.1%) than Fe3O4@MIP without ChCl-BuIM (83.2–88.9%). This finding confirms that the use of ChCl-BuIM improved both the selectivity and affinity of the MIP adsorbent towards naproxen. Competitive recognition studies of the Fe3O4@MIP-ChCl-BuIM using naproxen and structurally similar non-steroidal anti-inflammatory drugs revealed that the Fe3O4@MIP-ChCl-BuIM had high selectivity for naproxen. A cytotoxicity test showed that the synthesised ChCl-BuIM was non-toxic, as the human normal cell lines MCF-10A, and BEAS-2B maintained viability above 50%. These results show that Fe3O4@MIP-ChCl-BuIM has potential for use as a functional adsorption material for the removal of naproxen from water samples

Magnetic Deep Eutectic Solvents Based Adsorbents For The Removal Of Selected Non-Streoidal Antiinflammotary Drugs

In this study, material based on magnetic choline chloride-butyl imidazole (Fe3O4@ChCl-BuIM) was synthesise via simple co-precipitation method for removal of diclofenac and naproxen from water sample. The synthesised material was characterized by using analytical instrument such as Fourier transform infrared spectroscopy (FTIR), CHN elemental analyser, vibrating sample magnetometer (VSM), scanning electron microscope (SEM), transmission electron microscope (TEM), X-ray diffractometer (XRD), thermogravimetric analyser (TGA), and Brunauer-Emmet-Teller (BET) surface analyser. Preliminary adsorption study of Fe3O4@ChCl-BuIM has showed excellent adsorption capacity for removal of diclofenac and naproxen from water samples compared to unmodified Fe3O4. Both targeted analytes were attracted to the Fe3O4@ChCl-BuIM particles by U U interaction and hydrogen bonding, thus improved the adsorption capacity

Removal of phthalates in aqueos samples using non-ionic silicone surfactant mediated cloud point extraction via spectrophotometry [Penyingkiran ftalat dalam sampel akues menggunakan teknik pengekstrakan titik awan surfaktan silikon tidak berionik dengan spektrofotometri]

Removal of phthalates in environmental compartments become crucial in recent years due to the growing global concern about the health effects of phthalates. In this study, a greener method based on cloud point extraction procedure was developed for the removal of selected phthalates in environmental samples using non-ionic silicone surfactant (DC193C). The parameters affecting the extraction efficiency, such as the surfactant concentration, salt types, salt concentration, temperature and incubation time were evaluated and optimized. Good linearity with correlation coefficients (R2) in the range of 0.9963 – 0.9988 for all calibration curves was obtained. The proposed method was applied in removing the diethhylhexyl phthalate and dibutyl phthalate in river water samples under optimized conditions with satisfactory recoveries in the range of 82 – 98%. © 2019, Malaysian Society of Analytical Sciences. All rights reserved