Team-based learning (TBL): An Argument for Faculty’s Evaluation

Team-based learning (TBL) is increasingly used for presenting educational information to students in colleges of pharmacy. Several studies have shown a positive impact on students both in terms of academic performance and comprehension. Current literature does not provide the full perspective of faculty, who are incorporating this methodology into the classroom. Cross-sectional surveys and commentary within manuscripts describe mixed findings regarding the faculty’s perception of TBL. The aims of this paper are: 1) to describe why faculty evaluation of TBL is important, 2) to outline variables for consideration in faculty evaluations of TBL, and 3) to describe uses for the data from faculty evaluation of TBL

Conditional citizens? welfare rights and responsibilities in the late 1990s

In Britain the relationship between welfare rights and responsibilities has undergone change. A new welfare 'consensus' that emphasizes a citizen ship centred on notions of duty rather than rights has been built. This has allowed the state to reduce its role as a provider of welfare and also defend a position in which the welfare rights of some citizens are increas ingly conditional on those individuals meeting compulsory responsibili ties or duties. This concentration on individual responsibility/duty has undermined the welfare rights of some of the poorest members of society. Three levels of debate are considered within the article: academic, pol itical and 'grassroots'. The latter is included in an attempt to allow some 'bottom up' views into what is largely a debate dominated by social sci entists and politicians

Effects of temperature and microbial disruption on juvenile kelp Ecklonia radiata and its associated bacterial community

Ocean warming can affect the development and physiological responses of kelps, and under future climate change scenarios, increasing seawater temperatures pose a major threat to these habitat-forming species. However, little is known about the effects of warming on epiphytic bacterial communities and how an altered microbiome may interact with temperature stress, affecting the condition and survival of kelp, particularly of the potentially more vulnerable early life stages. Here, we tested the effects of thermal stress on the growth and physiological responses of juvenile kelp Ecklonia radiata in which their epiphytic bacterial community was experimentally disrupted using antimicrobials, simulating dysbiosis. We hypothesized that, under thermal stress (23°C, simulating a extreme scenario of ocean warming in Tasmania), kelp with a disrupted bacterial community would be more strongly affected than kelp with an undisrupted microbiome or kelp under ambient temperature (14°C) but with a disrupted microbiota. Thermal stress reduced growth, increased tissue bleaching and negatively affected net photosynthesis of kelp. In addition, a substantial change in the epiphytic bacterial community structure was also found under thermal stress conditions, with an increase in the abundance of potentially pathogenic bacterial groups. However, microbial disruption did not act synergistically with thermal stress to affect kelp juveniles. These results suggest that effects of elevated temperature on juvenile kelps is not microbially-mediated and that juveniles may be less susceptible to disruptions of their microbiome

Selective Breeding for a Behavioral Trait Changes Digit Ratio

The ratio of the length of the second digit (index finger) divided by the fourth digit (ring finger) tends to be lower in men than in women. This 2D∶4D digit ratio is often used as a proxy for prenatal androgen exposure in studies of human health and behavior. For example, 2D∶4D ratio is lower (i.e. more “masculinized”) in both men and women of greater physical fitness and/or sporting ability. Lab mice have also shown variation in 2D∶4D as a function of uterine environment, and mouse digit ratios seem also to correlate with behavioral traits, including daily activity levels. Selective breeding for increased rates of voluntary exercise (wheel running) in four lines of mice has caused correlated increases in aerobic exercise capacity, circulating corticosterone level, and predatory aggression. Here, we show that this selection regime has also increased 2D∶4D. This apparent “feminization” in mice is opposite to the relationship seen between 2D∶4D and physical fitness in human beings. The present results are difficult to reconcile with the notion that 2D∶4D is an effective proxy for prenatal androgen exposure; instead, it may more accurately reflect effects of glucocorticoids, or other factors that regulate any of many genes

Otitis Media in a New Mouse Model for CHARGE Syndrome with a Deletion in the Chd7 Gene

Otitis media is a middle ear disease common in children under three years old. Otitis media can occur in normal individuals with no other symptoms or syndromes, but it is often seen in individuals clinically diagnosed with genetic diseases such as CHARGE syndrome, a complex genetic disease caused by mutation in the Chd7 gene and characterized by multiple birth defects. Although otitis media is common in human CHARGE syndrome patients, it has not been reported in mouse models of CHARGE syndrome. In this study, we report a mouse model with a spontaneous deletion mutation in the Chd7 gene and with chronic otitis media of early onset age accompanied by hearing loss. These mice also exhibit morphological alteration in the Eustachian tubes, dysregulation of epithelial proliferation, and decreased density of middle ear cilia. Gene expression profiling revealed up-regulation of Muc5ac, Muc5b and Tgf-β1 transcripts, the products of which are involved in mucin production and TGF pathway regulation. This is the first mouse model of CHARGE syndrome reported to show otitis media with effusion and it will be valuable for studying the etiology of otitis media and other symptoms in CHARGE syndrome

Latitude, digit ratios, and Allen's and Bergmann's rules: a comment on Loehlin, McFadden, Medland, and Martin (2006)

Comments on an article by J. C. Loehlin, D. McFadden, S. E. Medland and N. G. Martin (see record 2007-07455-014). The authors investigated the relationship between latitude and digit ratio (2D:4D). Like digit ratio, height has been suggested to reflect physical masculinization. Height is also positively correlated with perceptual-verbal ability (in women) and mental rotation ability. Latitude effect may not be completely independent of the hypothesized organizational effects of testosterone. Sex ratios appear to be influenced by circulating hormone levels in the parents around the time of conception and sex ratios at birth appear to be male-biased towards the equator and relatively male-biased at high latitudes. Regardless, any link between organizational testosterone and stature on the one hand and digit ratio on the other, and inter-ethnic variation in all three physical traits, requires further investigation. We suggest that much of the variance in digit ratio attributable to latitude is actually due to an allometric relationship between body size and digit ratio across populations.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/83881/1/latitude_digit_ratios_a_comment_on_loehlin.pd