Psychological Capital and Quality of Work Life among employees in public sector: evidence from Ho Chi Minh City Department of Culture and Sports

In the modern world, employee s organizational performance is seen as one of the most important factor in developing an organization for both public and private sectors. The literature review also showed a lack of empirical research on the topic in the context of Vietnam, especially in the public sector about PsyCap in relation with Performance. Therefore, this study aims to examine the impact of PsyCap and Quality of work life on employee performance in public agencies such as Department of Culture and Sport in Ho Chi Minh City. 28 questions with the seven-point Likert scale were used to the research. Respondents in this study were 157 employees working full-time in this Department in Ho Chi Minh City. SPSS 20 and AMOS 20 were used to analyze the collected data. The research findings proved the significant effect of PsyCap Performance as well as QWL and performance in the public organizations in Ho Chi Minh City. This study provides not only better understanding of the subject but also the practical implications for personnel management of the organization

Psychological Capital and Quality of Work Life among employees in public sector: evidence from Ho Chi Minh City Department of Culture and Sports

In the modern world, employee s organizational performance is seen as one of the most important factor in developing an organization for both public and private sectors. The literature review also showed a lack of empirical research on the topic in the context of Vietnam, especially in the public sector about PsyCap in relation with Performance. Therefore, this study aims to examine the impact of PsyCap and Quality of work life on employee performance in public agencies such as Department of Culture and Sport in Ho Chi Minh City. 28 questions with the seven-point Likert scale were used to the research. Respondents in this study were 157 employees working full-time in this Department in Ho Chi Minh City. SPSS 20 and AMOS 20 were used to analyze the collected data. The research findings proved the significant effect of PsyCap Performance as well as QWL and performance in the public organizations in Ho Chi Minh City. This study provides not only better understanding of the subject but also the practical implications for personnel management of the organization

Multimodal analysis of methylomics and fragmentomics in plasma cell-free DNA for multi-cancer early detection and localization

Despite their promise, circulating tumor DNA (ctDNA)-based assays for multi-cancer early detection face challenges in test performance, due mostly to the limited abundance of ctDNA and its inherent variability. To address these challenges, published assays to date demanded a very high-depth sequencing, resulting in an elevated price of test. Herein, we developed a multimodal assay called SPOT-MAS (screening for the presence of tumor by methylation and size) to simultaneously profile methylomics, fragmentomics, copy number, and end motifs in a single workflow using targeted and shallow genome-wide sequencing (~0.55×) of cell-free DNA. We applied SPOT-MAS to 738 non-metastatic patients with breast, colorectal, gastric, lung, and liver cancer, and 1550 healthy controls. We then employed machine learning to extract multiple cancer and tissue-specific signatures for detecting and locating cancer. SPOT-MAS successfully detected the five cancer types with a sensitivity of 72.4% at 97.0% specificity. The sensitivities for detecting early-stage cancers were 73.9% and 62.3% for stages I and II, respectively, increasing to 88.3% for non-metastatic stage IIIA. For tumor-of-origin, our assay achieved an accuracy of 0.7. Our study demonstrates comparable performance to other ctDNA-based assays while requiring significantly lower sequencing depth, making it economically feasible for population-wide screening