Maximum LOD scores at DYX loci in the original dataset ‘r’ indicates maximization of lod score under recessive model, ‘d’ under dominant model.

<p>Maximum LOD scores at DYX loci in the original dataset ‘r’ indicates maximization of lod score under recessive model, ‘d’ under dominant model.</p

Pedigree of French-Canadian origin multiplex for RE (blue) and reading disability (red); arrow indicates proband.

<p>Pedigree of French-Canadian origin multiplex for RE (blue) and reading disability (red); arrow indicates proband.</p

Genome-wide LOD scores exceeding 2.0 in two-point MMLS linkage analysis for Reading Disability (RD) in original dataset; LOD scores for broader phenotypes (RD or Speech Sound Disorder (SSD) and RD or CentroTemporal Spikes (CTS)) at these loci also listed.

<p>Genome-wide LOD scores exceeding 2.0 in two-point MMLS linkage analysis for Reading Disability (RD) in original dataset; LOD scores for broader phenotypes (RD or Speech Sound Disorder (SSD) and RD or CentroTemporal Spikes (CTS)) at these loci also listed.</p

Multipoint analysis of Reading Disability on chromosome 7 in original dataset: maximum HLOD = 3.08 at D7S660 under a dominant mode of inheritance with 50% penetrance.

<p>Black line shows the multipoint linkage evidence using a heterogeneity LOD score (HLOD); dotted black line shows the LOD score; and blue line the information content.</p