Assessing and Comparing E-Mail Responsiveness in the Bavarian Public Sector

E-mail is the most important electronic communication medium for governments with their constituents. While there are a lot of matur ity models and benchmarking studies focusing on the tech nological and organizational integration of information technology in governments, the “customer side” of e-government maturity has been often neglected. Replicating studies from Australia, New Zealand, Slovenia and Denmark, this study explores the responsiveness concerning customer-government e-mail correspondence for the Bavarian Public Sector. Our study assesses the response rate and quality of 375 e-mails send to public administrations in Bavaria. Our results show that the Bavarian Public Administration has a poor responsiveness compared to other countries in terms of both quantity and quality. Based on our results, we provide recommendations for future research and practice

LEVERAGE ONCE, EARN REPEATEDLY – CAPABILITIES FOR CREATING AND APPROPRIATING VALUE IN CLOUD PLATFORM ECOSYSTEMS

Information technology (IT) advancements enabled new delivery models (i.e. Cloud Computing), thereby facilitating the emergence of new business models in the IT industry, such as Cloud platform ecosystems. With their growing acceptance and diffusion in practice, we need a deeper understanding of their IT capabilities in order to implement their business model, thereby creating and appropriating value. We draw on empirical data from four case studies of Cloud platform ecosystems utilizing a framework on IT-enabled business models for data analysis. We found four key motivations for inter-firm collaboration that each generated business model requirements specified in the context of Cloud platform ecosystems. These drive the development of unique B2B IT capabilities enabling value crea-tion and appropriation mechanisms. We propose three dyadic (relation-specific) IT customization and two network IT standardization (network-oriented) capabilities based on our cross case analysis. Fur-thermore, we describe prevalent value creation and appropriation mechanisms and suggest two addi-tional mechanisms grounded in the data: downstream capabilities and platform resourcing. We pro-vide a possible reasoning on the underlying logic of IT capabilities, value creation and appropriation of Cloud platform ecosystems

Up in the cloud: Understanding the chasm between expectations and reality

CEOs increasingly demand their IT function to fully exploit the opportunities of cloud computing for their company. At the same time, we observe that employees make experiences with cloud services in their private life, which they seamlessly transfer and expect in the workplace - a phenomenon called cloud consumerization. Thereby, employees use self-deployed cloud services for solving business problems which they find more useful than the IT products provided by work. In light of these revolutionary changes, we propose that user experiences and outcomes are contingent on the process through which cloud services are adopted in companies. Systemizing cloud adoption as a continuum of top-down and bottom-up processes, we assume that adoption processes are distinct with respect to users’ social and governance context. In this paper, we outline the theoretical and methodological foundation, provide details on the expected theoretical contributions and give information regarding next steps of our research project

A systemizing research framework for Web 2.0

Web 2.0 has recently been one of the most discussed topics in Information Systems science and practice. However, little consensus is found on what its components and characteristics actually are and what a comprehensive conceptualization might look like. This paper tries to shed light on these questions by systemizing the phenomenon’s characteristics in a hierarchical framework. In a first step, we apply content and cluster analysis on contributions of the field and inductively identify 103 raw categories which are then clustered into ten subcategories and two main categories. Namely these identified main categories of Web 2.0 are: ‘Technological Characteristics’ and ‘Socioeconomic Characteristics’. In a second step, we pretest and optimize the constructs for applicability and ambiguities and finally apply them to evaluate on the importance and weighting of the discovered subcategories. The resulting framework is found to comply with common quality measures for content analysis and classification schemes. It can be used to analyze and explore economic or social phenomena associated with Web 2.0 in a systematic manner

How cloud computing impacts stock market prices

Cloud computing is an evolution of computing technology and reflects a shift in the way it is delivered to businesses and individuals. Enterprises can significantly lower their cost of ownership, reduce time to value and faster adapt to changing needs in a globalized economy. Despite research and practice predict productivity increases and cost savings when migrating to the cloud one question remains unanswered: Does the adoption of cloud computing increase the market value of the firm? We try to answer this question by applying the event study methodology on companies that recently announced the deployment of cloud computing. Overall, we find significant positive abnormal returns. We find that investors specifically reward innovative and strategically motivated adoption of cloud computing. As a key implication of our results, we recommend in particular IT executives in large companies within the service industry to reassess their portfolio and foster the adoption of strategic and innovative cloud services

Transforming Growth Factor β1 Oppositely Regulates the Hypertrophic and Contractile Response to β-Adrenergic Stimulation in the Heart

BACKGROUND: Neuroendocrine activation and local mediators such as transforming growth factor-β₁ (TGF-β₁) contribute to the pathobiology of cardiac hypertrophy and failure, but the underlying mechanisms are incompletely understood. We aimed to characterize the functional network involving TGF-β₁, the renin-angiotensin system, and the β-adrenergic system in the heart. METHODS: Transgenic mice overexpressing TGF-β₁ (TGF-β₁-Tg) were treated with a β-blocker, an AT₁-receptor antagonist, or a TGF-β-antagonist (sTGFβR-Fc), were morphologically characterized. Contractile function was assessed by dobutamine stress echocardiography in vivo and isolated myocytes in vitro. Functional alterations were related to regulators of cardiac energy metabolism. RESULTS: Compared to wild-type controls, TGF-β₁-Tg mice displayed an increased heart-to-body-weight ratio involving both fibrosis and myocyte hypertrophy. TGF-β₁ overexpression increased the hypertrophic responsiveness to β-adrenergic stimulation. In contrast, the inotropic response to β-adrenergic stimulation was diminished in TGF-β₁-Tg mice, albeit unchanged basal contractility. Treatment with sTGF-βR-Fc completely prevented the cardiac phenotype in transgenic mice. Chronic β-blocker treatment also prevented hypertrophy and ANF induction by isoprenaline, and restored the inotropic response to β-adrenergic stimulation without affecting TGF-β₁ levels, whereas AT₁-receptor blockade had no effect. The impaired contractile reserve in TGF-β₁-Tg mice was accompanied by an upregulation of mitochondrial uncoupling proteins (UCPs) which was reversed by β-adrenoceptor blockade. UCP-inhibition restored the contractile response to β-adrenoceptor stimulation in vitro and in vivo. Finally, cardiac TGF-β₁ and UCP expression were elevated in heart failure in humans, and UCP--but not TGF-β₁--was downregulated by β-blocker treatment. CONCLUSIONS: Our data support the concept that TGF-β₁ acts downstream of angiotensin II in cardiomyocytes, and furthermore, highlight the critical role of the β-adrenergic system in TGF-β₁-induced cardiac phenotype. Our data indicate for the first time, that TGF-β₁ directly influences mitochondrial energy metabolism by regulating UCP3 expression. β-blockers may act beneficially by normalizing regulatory mechanisms of cellular hypertrophy and energy metabolism

Inflammation, ECG changes and pericardial effusion: Whom to biopsy in suspected myocarditis?

The role of endomyocardial biopsies in patients with clinically suspected acute myocarditis, myocarditis in the past, and dilated cardiomyopathy is discussed controversially. In fact, it is still under discussion whether information obtained from endomyocardial biopsies is relevant for further clinical decisions. Therefore this Critical Perspective will deal with the question, which patient should undergo endomyocardial biopsy investigations for an etiopathogenic differentiation of the disease and for the possible choice of immunomodulatory treatment strategies