Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity

Many genetic loci affect circulating lipid levels, but it remains unknown whether lifestyle factors, such as physical activity, modify these genetic effects. To identify lipid loci interacting with physical activity, we performed genome-wide analyses of circulating HDL cholesterol, LDL cholesterol, and triglyceride levels in up to 120,979 individuals of European, African, Asian, Hispanic, and Brazilian ancestry, with follow-up of suggestive associations in an additional 131,012 individuals. We find four loci, in/near CLASP1, LHX1, SNTA1, and CNTNAP2, that are associated with circulating lipid levels through interaction with physical activity; higher levels of physical activity enhance the HDL cholesterol-increasing effects of the CLASP1, LHX1, and SNTA1 loci and attenuate the LDL cholesterol- increasing effect of the CNTNAP2 locus. The CLASP1, LHX1, and SNTA1 regions harbor genes linked to muscle function and lipid metabolism. Our results elucidate the role of physical activity interactions in the genetic contribution to blood lipid levels

Comparing branch biomass prediction equations for <i>Abies</i><i>baisamea</i>

The use of sapwood cross-sectional area at breast height (S) was compared with the use of diameter at breast height (D) and total height (H) for predicting branch weight per tree (B). Data obtained by destructive sampling of 58 balsam fir (Abiesbalsamea (L.) Mill.) trees growing in western and northern Newfoundland were used to fit a simple linear and a nonlinear model using D2H and to fit a simple linear and two nonlinear models using S. Coefficients of determination and standard error of estimates were similar for all equations. There were large differences in estimates of branch weight per hectare between equations for 25 cruised stands. The relationship between B and leaf area was used to evaluate the accuracy of stand estimates. The allometric equation using S as the independent variable provided the most accurate estimates. </jats:p

Fast semi-supervised segmentation of in-situ tree color images

International audienceIn this paper we present an original semi-supervised method for the segmentation of in situ tree color images which combines color quantization, adaptive fragmentation of learning areas defined by the human operator and labeling propagation. A mathematical morphology post-processing is introduced to emphasize the narrow and thin structures which characterize branches. Applied in the L*a*b* color system, this method is well adapted to easily adjust the learning set so that the resultant labeling corresponds to the accuracy achieved by the human operator. The method has been embarked and evaluated on a tablet to help tree professionals in their expertise or diagnosis. The images, acquired and processed with a mobile device, present more or less complex background both in terms of content and lightness, more or less dense foliage and more or less thick branches. Results are good on images with soft lightness without direct sunlight

Oak forest carbon and water simulations: model intercomparisons and evaluations against independent data

Models represent our primary method for integration of small-scale, process-level phenomena into a comprehensive description of forest-stand or ecosystem function. They also represent a key method for testing hypotheses about the response of forest ecosystems to multiple changing environmental conditions. This paper describes the evaluation of 13 stand-level models varying in their spatial, mechanistic, and temporal complexity for their ability to capture intra- and interannual components of the water and carbon cycle for an upland, oak-dominated forest of eastern Tennessee. Comparisons between model simulations and observations were conducted for hourly, daily, and annual time steps. Data for the comparisons were obtained from a wide range of methods including: eddy covariance, sapflow, chamber-based soil respiration, biometric estimates of stand-level net primary production and growth, and soil water content by time or frequency domain reflectometry. Response surfaces of carbon and water flux as a function of environmental drivers, and a variety of goodness-of-fit statistics (bias, absolute bias, and model efficiency) were used to judge model performance. A single model did not consistently perform the best at all time steps or for all variables considered. Intermodel comparisons showed good agreement for water cycle fluxes, but considerable disagreement among models for predicted carbon fluxes. The mean of all model outputs, however, was nearly always the best fit to the observations. Not surprisingly, models missing key forest components or processes, such as roots or modeled soil water content, were unable to provide accurate predictions of ecosystem responses to short-term drought phenomenon. Nevertheless, an inability to correctly capture short-term physiological processes under drought was not necessarily an indicator of poor annual water and carbon budget simulations. This is possible because droughts in the subject ecosystem were of short duration and therefore had a small cumulative impact. Models using hourly time steps and detailed mechanistic processes, and having a realistic spatial representation of the forest ecosystem provided the best predictions of observed data. Predictive ability of all models deteriorated under drought conditions, suggesting that further work is needed to evaluate and improve ecosystem model performance under unusual conditions, such as drought, that are a common focus of environmental change discussions