Анализ термодинамических параметров нефтепровода с предварительным подогревом нефти в условиях Севера

Объектом исследования является трубопровод, на котором применяется технология перекачки нефти с предварительным подогревом. Цель работы – определить влияние термодинамических характеристик трубопроводного транспорта нефти в условиях Севера на эффективность технологии перекачки нефти с предварительным подогревом. В процессе исследования проводились гидравлические и тепловые расчеты, расчет оптимальной температуры транспорта, расчет экономической эффективности использования технологии транспорта с подогревом. Рассмотрены вопросы корректного описания вязкостно-температурной характеристики нефти для определения оптимальной температуры подогрева нефти, влияния термодинамических параметров системы «нефтепровод-окружающая среда» на эффективность применения предварительного подогрева.The object of research is the hot oil pipeline. Purpose - to determine the influence of the thermodynamic characteristics of the pipeline transport of oil in the North on the effectiveness of technology of hot oil transfer. The study carried out hydraulic and thermal calculations, the calculation of optimal transport temperature, calculation of economic efficiency of use of hot oil transport. The questions of the correct description of viscosity-temperature characteristics of the oil to determine the optimum temperature of heating oil, the effect of thermodynamic parameters of the system "pipeline-environment" on the effectiveness of transport. Presents measures for health and safety point of operation of oil heating, environmental protection, technical and economic part

Understanding hereditary diseases using the dog and human as companion model systems

Animal models are requisite for genetic dissection of, and improved treatment regimens for, human hereditary diseases. While several animals have been used in academic and industrial research, the primary model for dissection of hereditary diseases has been the many strains of the laboratory mouse. However, given its greater (than the mouse) genetic similarity to the human, high number of naturally occurring hereditary diseases, unique population structure, and the availability of the complete genome sequence, the purebred dog has emerged as a powerful model for study of diseases. The major advantage the dog provides is that it is afflicted with approximately 450 hereditary diseases, about half of which have remarkable clinical similarities to corresponding diseases of the human. In addition, humankind has a strong desire to cure diseases of the dog so these two facts make the dog an ideal clinical and genetic model. This review highlights several of these shared hereditary diseases. Specifically, the canine models discussed herein have played important roles in identification of causative genes and/or have been utilized in novel therapeutic approaches of interest to the dog and human