A global bifurcation theorem for a multiparameter positone problem and its application to the one-dimensional perturbed Gelfand problem

We study the global bifurcation and exact multiplicity of positive solutions for u 00(x) + λ fε(u) = 0, − 1 0 is a bifurcation parameter, ε ∈ Θ is an evolution parameter, and Θ ≡ (σ1, σ2) is an open interval with 0 ≤ σ1 < σ2 ≤ ∞. Under some suitable hypotheses on fε , we prove that there exists ε0 ∈ Θ such that, on the (λ, kuk∞)-plane, the bifurcation curve is S-shaped for σ1 < ε < ε0 and is monotone increasing for ε0 ≤ ε < σ2. We give an application to prove global bifurcation of bifurcation curves for the one-dimensional perturbed Gelfand problem

Design of High Efficiency Illumination for LED Lighting

A high efficiency illumination for LED street lighting is proposed. For energy saving, this paper uses Class-E resonant inverter as main electric circuit to improve efficiency. In addition, single dimming control has the best efficiency, simplest control scheme and lowest circuit cost among other types of dimming techniques. Multiple serial-connected transformers used to drive the LED strings as they can provide galvanic isolation and have the advantage of good current distribution against device difference. Finally, a prototype circuit for driving 112 W LEDs in total was built and tested to verify the theoretical analysis

Advanced Techniques for Computational and Information Sciences

New techniques in computational and information sciences have played an important role in keeping advancing the so called knowledge economy. Advanced techniques have been introduced to or emerging in almost every field of the scientific world for hundreds of years, which has been accelerated since the late 1970s when the advancement in computers and digital technologies brought the world into the Information Era. In addition to the rapid development of computational intelligence and new data fusion techniques in the past thirty years [1–4], mobile and cloud computing, grid computing driven numeric computation models, big data intelligence, and other emerging technologies have not only expanded the scope of traditional simulation and modelling in many scientific and engineering disciplines [5–8] but also enabled the fusion of traditional and contemporary methods in almost every field in the world [9–11]

Safety and Efficacy of Tien-Hsien Liquid Practical in Patients with Refractory Metastatic Breast Cancer: A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Phase IIa Trial

To evaluate the safety and efficacy of Tien-Hsien Liquid Practical (THL-P), a Chinese herbal mixture, in patients with refractory metastatic breast cancer, we performed a randomized, double-blind, placebo-controlled, parallel-group, phase IIa pilot trial. Patients were randomly assigned to either receive THL-P or matching placebo and followed up every 4 weeks for 24 weeks. The primary endpoint was changes in the global health status/quality of life (GHS/QOL) scale. The secondary endpoints were changes in functional and symptom scales, immunomodulating effects, and adverse events. Sixty-three patients were enrolled between June 2009 and June 2011. The intent-to-treat population included 28 patients in the THL-P group and 11 patients in the placebo group. Compared to the placebo group, the THL-P group had significant improvement from baseline to last visit in GHS/QOL (41.7 versus −33.3; P < 0.05), CD3, CD4/CD8, CD19, CD16+56 positive cells (P < 0.05), and higher levels of physical, role, emotional, and cognitive functioning, as well as decreased fatigue and systemic side effects. Treatment-related adverse events were mild constipation and localized itching, and no serious adverse events were reported. THL-P appears to be a safe alternative adjuvant treatment for patients with refractory metastatic breast cancer, as it effectively improves QOL and palliates cancer-related symptoms

Applications of Differential CDMA Schemes and Control Technology for Distribution Substations

This paper presents an approach to achieve monitoring and control of distribution systems in a distribution substation using power-line communication (PLC) combined with Hadamard code. Four different techniques, i.e., binary phase shift keying (BPSK), quadrature phase shift keying (QPSK), 16-quadrature amplitude modulator (QAM) and 64-QAM in code division multiple access (CDMA), are employed. With spreading-spectrum modulation and demodulation in the studied PLC system, the proposed approach can achieve reliable high-speed information transmission through power lines. With Hadamard code, the signals corresponding to different relays are orthogonal to each other and the interference among them can be reduced. The proposed approach has the advantages of high-speed detection, bi-direction communication, reading and backup data, control and turn-off functions, displaying the real-time system information, etc. When 100 kHz is used as the carrier frequency for 256 relays under power-line noise below 14 dB, the simulation results show that the bit error rate (BER) is less than 10-5 . The proposed scheme can be applied to the smart-grid distribution substation of the studied distribution systems