Understanding collaborative supply chain relationships through the application of the Williamson organisational failure framework

Many researchers have studied supply chain relationships however, the preponderance of open markets situations and ‘industry-style’ surveys have reduced the empirical focus on the dynamics of long-term, collaborative dyadic relationships. Within the supply chain the need for much closer, long-term relationships is increasing due to supplier rationalisation and globalisation (Spekman et al, 1998) and more information about these interactions is required. The research specifically tested the well-accepted Williamson’s (1975) Economic Organisations Failure Framework as a theoretical model through which long term collaborative relationships can be

Long Term Collaborative Business Relationships: The Impact of Trust and C3 Behaviour

Long-term, collaborative business relationships are like marriages where tolerance, forbearance and some reduction of freedom as well as innovation are necessary to ensure success. Trust and co-operative behaviours are known to be essential ingredients in securing an environment of continuous improvement but, how they are correlated has yet to be tested. The paper describes a research project within a sample of long-term monopoly businesses as a novel approach to bringing trust and cooperation, co-ordination and collaboration (C3 Behaviour) into sharper focus without competitive distractions. It was found that a correlation between trust and C3 Behaviour and the success of the collaborative relationship exists

Solar residential heating and cooling system

System has been placed in operation to verify technical feasibility of using solar energy to provide residential heating and cooling. Complete system analysis was performed to provide design information

Solar residential heating and cooling system development test program

A solar heating and cooling system is described, which was installed in a simulated home at Marshall Space Flight Center. Performance data are provided for the checkout and initial operational phase for key subsystems and for the total system. Valuable information was obtained with regard to operation of a solar cooling system during the first summer of operation. Areas where improvements and modifications are required to optimize such a system are discussed

CD14 is a ligand for the integrin α4β1

AbstractCell adhesion mediated by the integrin α4β1 plays a key role in many biological processes reflecting both the number and functional significance of α4β1 ligands. The lipopolysaccharide (LPS) receptor, CD14, is a GPI-linked cell surface glycoprotein with a wide range of reported functions and associations, some of which overlap with that of α4β1. This overlap led us to test the specific hypothesis that α4β1 and CD14 interact directly. Jurkat T cells (α4β1+) were found to adhere to a recombinant CD14-Fc protein via α4β1, whilst K562 cells (α4β1−) did not. However, stable reexpression of the α4-subunit conferred this ability. The adhesion of both cell types to CD14 displayed activation state-dependent binding very similar to the interaction of α4β1 with its prototypic ligand, VCAM-1. In solid-phase assays, CD14-Fc bound to affinity-purified α4β1 in a dose-dependent manner that was induced by activating anti-β1 mAbs. Finally, in related experiments, JY cells (α4β7+) were also found to attach to CD14-Fc in an α4-dependent manner. In summary, CD14 is a novel ligand for α4β1, exhibiting similar activation-state dependent binding characteristics as other α4β1 ligands. The biological relevance of this interaction will be the subject of further studies

The twisted Floer homology of torus bundles

Given a torus bundle $Y$ over the circle and a cohomology class $[\omega]\in H^2(Y;\mathbb{Z})$ which evaluates nontrivially on the fiber, we compute the Heegaard Floer homology of $Y$ with twisted coefficients in the universal Novikov ring.Comment: 12 pages, 1 figur