Blockchain-based fake news traceability and verification mechanism

The rapid development of the Internet and Internet of Things has rapidly introduced human society into the information age, and the way of fake news production has been updated, which has greatly affected the normal life of human beings. In order to identify worthless fake news and trace massive fake news data from unknown sources, and share valuable news data to fully disseminate effective real news, news owners usually store news data in cloud. Users of IoT terminals can access news data on demand without storing it locally. However, the authenticity of the fictive newspaper numbers source, which is easy to destroy, and the social media platform. Besides, when massive news data is saved on cloud server, the news owners have to at the risk of lose physical control over news data and it will face the risk of fake news being disseminated and real news being falsified. Thus, this paper proposes a novel mechanism for secure storage of news data using blockchain technology. Firstly, traceability and verification of fake news data is improved by the cooperative storage model on and off the chain. Secondly due to the inability of past polynomial commitment to update the commitment, we will be a hindrance to use polynomial commitment to build a secure authentication protocol. Therefore, in this paper, we design the update algorithm for polynomial commitment in order to be able to guarantee the consistency of on-chain and blockchain database news data

Data_Sheet_2_Cuproptosis key gene FDX1 is a prognostic biomarker and associated with immune infiltration in glioma.CSV

Recent studies have found that the protein encoded by the FDX1 gene is involved in mediating Cuproptosis as a regulator of protein lipoylation and related to immune response process of tumors. However, the specific biological function of FDX1 in glioma is currently unclear. To explore the potential function of FDX1, this study explored the correlation between the expression of FDX1 in cancers and survival prognosis by analyzing the public databases of GEPIA and Cbioportal. Immune infiltration was analyzed by the TIMER2.0 database in tumors. The possible biological processes and functions of FDX1-related in glioma were annotated through gene enrichment. Relationship between Cuproptosis and autophagy was explored through gene co-expression studies. Summary and conclusions of this study: (1) FDX1 is highly expressed in gliomas and associated with poor prognosis in low-grade gliomas (LGG). (2) Gene annotation indicates that FDX1 is mainly involved in the tumor protein lipoylation and cell death. (3) FDX1 expression is positively correlated with the infiltration of immune cells. (4) LIPT2 and NNAT, two other genes involved in lipoylation, may be unidentified marker gene for Cuproptosis. And the Cuproptosis genes related to FDX1 were positively correlated with the expression of autophagy marker genes Atg5, Atg12, and BECN-1. This evidence suggests that there may be some interaction between FDX1 mediated Cuproptosis and autophagy. In summary, FDX1 may serve as a potential immunotherapy target and prognostic marker for Glioma.</p

Sources and symptoms of stress among nurses in the first Chinese anti-Ebola medical team during the Sierra Leone aid mission: A qualitative study

Objective: This study investigated the sources of stress, corresponding symptoms, and stress relief among nurses of the first Chinese anti-Ebola medical team during the Sierra Leone aid mission. Method: A purposive sampling method was used and 10 nurses were selected from the first Chinese anti-Ebola medical team that was dispatched to Sierra Leone. Data were collected via phone and semi-structured interviews, then analyzed using Colaizzi's seven-step method. Results: The data showed three major themes: (1) The causes of stress during the Sierra Leone aid mission mainly related to unsafety, responsibility, and unfamiliarity; (2) Physical, cognitive, emotional, and behavioral symptoms were documented; (3) Nurses experienced relief from stress after the mission. Conclusion: Targeted measures, proper responses and good community support can effectively lower stress among nurses on anti-Ebola missions. Keywords: Anti-Ebola medical team, Nurses, Pressure, Qualitative researc

Data_Sheet_1_Cuproptosis key gene FDX1 is a prognostic biomarker and associated with immune infiltration in glioma.CSV

Recent studies have found that the protein encoded by the FDX1 gene is involved in mediating Cuproptosis as a regulator of protein lipoylation and related to immune response process of tumors. However, the specific biological function of FDX1 in glioma is currently unclear. To explore the potential function of FDX1, this study explored the correlation between the expression of FDX1 in cancers and survival prognosis by analyzing the public databases of GEPIA and Cbioportal. Immune infiltration was analyzed by the TIMER2.0 database in tumors. The possible biological processes and functions of FDX1-related in glioma were annotated through gene enrichment. Relationship between Cuproptosis and autophagy was explored through gene co-expression studies. Summary and conclusions of this study: (1) FDX1 is highly expressed in gliomas and associated with poor prognosis in low-grade gliomas (LGG). (2) Gene annotation indicates that FDX1 is mainly involved in the tumor protein lipoylation and cell death. (3) FDX1 expression is positively correlated with the infiltration of immune cells. (4) LIPT2 and NNAT, two other genes involved in lipoylation, may be unidentified marker gene for Cuproptosis. And the Cuproptosis genes related to FDX1 were positively correlated with the expression of autophagy marker genes Atg5, Atg12, and BECN-1. This evidence suggests that there may be some interaction between FDX1 mediated Cuproptosis and autophagy. In summary, FDX1 may serve as a potential immunotherapy target and prognostic marker for Glioma.</p