蘇軾前身故事的真相與改寫

北宋禪僧惠洪最早記録了蘇軾前身是雲門宗禪僧五祖師戒的故事。他不僅構建了這個故事，也一手記録了五祖師戒形象的所有元素。惠洪所爲可能與其祖師黄龍慧南叛出雲門宗這一事件相關，他通過建構蘇軾前身故事及五祖師戒形象，來維護黄龍慧南的聲名，表明其並非背叛雲門宗，而是真正傳承雲門法脈。後來蘇軾前身故事被世俗社會引入戲曲小説，並將其與紅蓮故事拼合，展現出與士大夫話語不一樣的面貌，成爲禪宗在世俗社會的傳法手段。五祖師戒在小説戲曲中被訛變爲五戒禪師，這個新形象成爲流傳最廣的蘇軾前身樣態

3D fusion between fluoroscopy angiograms and SPECT myocardial perfusion images to guide percutaneous coronary intervention

Background Percutaneous coronary intervention (PCI) in stable coronary artery disease (CAD) is commonly triggered by abnormal myocardial perfusion imaging (MPI). However, due to the possibilities of multivessel disease, serial stenoses and variability of coronary artery perfusion distribution, an opportunity exists to better align anatomic stenosis with perfusion abnormalities to improve revascularization decisions. This study aims to develop a multi-modality fusion approach to assist decision-making for PCI. Methods and Results Coronary arteries from fluoroscopic angiography (FA) were reconstructed into 3D artery anatomy. Left ventricular (LV) epicardial surface was extracted from SPECT. The artery anatomy and epicardial surface were non-rigidly fused. The accuracy of the 3D fusion was evaluated via both computer simulation and real patient data. Simulated FA and MPI were integrated and then compared with the ground truth from a digital phantom. The distance-based mismatch errors between simulated fluoroscopy and phantom arteries were 1.86 ± 1.43 mm for left coronary arteries (LCA) and 2.21 ± 2.50 mm for right coronary arteries (RCA). FA and SPECT images in 30 patients were integrated and then compared with the ground truth from CT angiograms. The distance-based mismatch errors between the fluoroscopy and CT arteries were 3.84 ± 3.15 mm for LCA and 5.55 ± 3.64 mm for RCA. The presence of the corresponding fluoroscopy and CT arteries in the AHA-17-segment model agreed well with a Kappa value of 0.91 (CI 0.89-0.93) for LCA and a Kappa value of 0.80 (CI 0.67-0.92) for RCA. Conclusions Our fusion approach is technically accurate to assist PCI decision-making and is clinically feasible to be used in the catheterization laboratory. Future studies are necessary to determine if fusion improves PCI-related outcomes

Tau-PET imaging in Parkinson's disease: a systematic review and meta-analysis

BackgroundPathological tau accumulates in the cerebral cortex of Parkinson's disease (PD), resulting in cognitive deterioration. Positron emission tomography (PET) can be used for in vivo imaging of tau protein. Therefore, we conducted a systematic review and meta-analysis of tau protein burden in PD cognitive impairment (PDCI), PD dementia (PDD), and other neurodegenerative diseases and explored the potential of the tau PET tracer as a biomarker for the diagnosis of PDCI.MethodsPubMed, Embase, the Cochrane Library, and Web of Science databases were systematically searched for studies published till 1 June 2022 that used PET imaging to detect tau burden in the brains of PD patients. Standardized mean differences (SMDs) of tau tracer uptake were calculated using random effects models. Subgroup analysis based on the type of tau tracers, meta-regression, and sensitivity analysis was conducted.ResultsA total of 15 eligible studies were included in the meta-analysis. PDCI patients (n = 109) had a significantly higher tau tracer uptake in the inferior temporal lobe than healthy controls (HCs) (n = 237) and had a higher tau tracer uptake in the entorhinal region than PD with normal cognition (PDNC) patients (n = 61). Compared with progressive supranuclear palsy (PSP) patients (n = 215), PD patients (n = 178) had decreased tau tracer uptake in the midbrain, subthalamic nucleus, globus pallidus, cerebellar deep white matter, thalamus, striatum, substantia nigra, dentate nucleus, red nucleus, putamen, and frontal lobe. Tau tracer uptake values of PD patients (n = 178) were lower than those of patients with Alzheimer's disease (AD) (n = 122) in the frontal lobe and occipital lobe and lower than those in patients with dementia with Lewy bodies (DLB) (n = 55) in the occipital lobe and infratemporal lobe.ConclusionIn vivo imaging studies with PET could reveal region-specific binding patterns of the tau tracer in PD patients and help in the differential diagnosis of PD from other neurodegenerative diseases.Systematic review registrationhttps://www.crd.york.ac.uk/PROSPERO/

Interfacial Polycondensation Synthesis of Optically Sensitive Polyurea Microcapsule

TMPTA prepolymer resin and photoinitiators of ITX/TPO had been encapsulated in core-shell structured microcapsules as optical responding ingredients based on interfacial polycondensation method, and polyurea structured microcapsule shell had been formed on the sheared O/W interface. The synthesized microcapsule had regular core-shell structure with the diameter of about 0.455 m and shell thickness of about 40 nm. UV-visible absorption spectra indicated that the encapsulated ITX and TPO photoinitiators could efficiently absorb UV irradiation. Under exposure, the C=C bonds absorbance of the microencapsulated TMPTA decreased rapidly and then nearly unchanged during further exposure after 30 s. This implied that the optical response was achieved by C=C bond cleavage of TMPTA monomer initiated by the photoinitiator radicals, to form network polymers in microcapsules. The relative crosslinking rate was about 50%. Due to core polymer formation, the thermal phase change temperature of exposed microcapsules was narrowed and ranged from 105 to 205 ∘ C, compared with that from 125 to 260 ∘ C of unexposed microcapsules. Furthermore, the image density decrease at longer irradiation time had also verified the optical responding function of the synthesized microcapsules in macroscopic viewpoint

Research on Bi-level Cooperative Robust Planning of Distributed Renewable Energy in Incremental Distribution Network Considering Demand Response

The paper constructs a two-level collaborative planning model for incremental distribution network considering demand response and distributed renewable energy access. In the upper model, the goal is to minimize the investment cost of the distribution network, and the lower model takes the system's operating cost optimally, fully considers the uncertainty of renewable energy output, and introduces robust optimization to solve it. It can be seen from the simulation results that the consideration of demand response in the distribution network planning is conducive to delaying investment costs, enhancing power user load flexibility, and effectively avoiding load shedding and other problems. The research results lay the foundation for the feasibility of demand response resources participating in power grid plannin

Analysis of Key Aroma Components of Three Representative Oolong Tea Varieties by Stir Bar Sorptive Extraction Combined with Gas Chromatography-Olfactory-Mass Spectrometry

Stir bar sorptive extraction (SBSE) combined with gas chromatography-olfactory-mass spectrometry (GC-O-MS) was used to identify and describe the key aroma components of three representative oolong tea varieties, Huangdan, Tieguanyin and Jinguanyin. Comparative analysis was conducted in terms of odor activity value (OAV), aroma character impact (ACI) value and sensory evaluation. The sensory evaluation showed that each variety showed obvious aroma characteristics. Huangdan oolong tea had an obvious floral aroma as well as a slight milky aroma. Tieguanyin oolong tea had a strong floral aroma. Jinguanyin oolong tea had a sweet fruity aroma as well as a slight woody aroma. According to the results of OAV and GC-O-MS analysis, geraniol, phytol, methyl jasmonate, trans-nerol tertiary alcohol, 2-nonone, and phenyl ethanol were identified as key aroma components in Huangdan oolong tea, which provided it with clean and high floral aroma and obvious milky aroma characteristics. In Tieguanyin oolong tea, linalool, 3,5-octylodiene-2-one, linalool oxide, cis-jasmonone, dehydrolinalool, and α-terpineol showed diverse floral aromas, which were closely related to the characteristic aroma of Tieguanyin oolong tea. The key aroma components identified in Jinguanyin oolong tea included linalool, canalaldehyde, geranyl acetone, cis-jasmonone and isoeugenol, which were responsible for the characteristic sweet floral and woody aromas of Jinguanyin oolong tea