1,648 research outputs found

    EFFECTS OF WHOLE BODY VIBRATION TRAINING ON KNEE EXTENSOR MUSCLE STRENGTH AND RATE OF FORCE DEVELOPMENT

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    This study compared the effects of 8-week whole-body vibration (WBV) training programs on knee extensor muscle strength and rate of force development. Twenty physically active male subjects were randomly assigned to a whole-body vibration training group (WBV; n =10) or a sham training group (SHAM; n = 10). Maximal voluntary isometric joint moment, rate of force development (RFD) and contractile impulse of the knee extensors were assessed before and after the training period. There were significant differences between WBV and sham groups on improvement percentage of maximum joint moment, RFD and contractile impulse in knee extensor. We concluded that not only knee extensor muscle strength could be enhanced but also muscle contractile abilty could be faster after a 8-week WBV training program

    When Social Influence Meets Item Inference

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    Research issues and data mining techniques for product recommendation and viral marketing have been widely studied. Existing works on seed selection in social networks do not take into account the effect of product recommendations in e-commerce stores. In this paper, we investigate the seed selection problem for viral marketing that considers both effects of social influence and item inference (for product recommendation). We develop a new model, Social Item Graph (SIG), that captures both effects in form of hyperedges. Accordingly, we formulate a seed selection problem, called Social Item Maximization Problem (SIMP), and prove the hardness of SIMP. We design an efficient algorithm with performance guarantee, called Hyperedge-Aware Greedy (HAG), for SIMP and develop a new index structure, called SIG-index, to accelerate the computation of diffusion process in HAG. Moreover, to construct realistic SIG models for SIMP, we develop a statistical inference based framework to learn the weights of hyperedges from data. Finally, we perform a comprehensive evaluation on our proposals with various baselines. Experimental result validates our ideas and demonstrates the effectiveness and efficiency of the proposed model and algorithms over baselines.Comment: 12 page

    Signatures of strong correlation effects in resonant inelastic x-ray scattering studies on cuprates

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    Recently, spin excitations in doped cuprates have been measured using resonant inelastic x-ray scattering. The paramagnon dispersions show the large hardening effect in the electron-doped systems and seemingly doping independence in the hole-doped systems, with the energy scales comparable to that of the antiferromagnetic (AFM) magnons. This anomalous hardening effect and the lack of softening were partially explained by using the strong-coupling t−J model but with a three-site term [Nat. Commun. 5, 3314 (2014)], although the hardening effect is already present even without the latter. By considering the t−t′−t"−J model and using the slave-boson mean-field theory, we obtain, via the spin-spin susceptibility, the spin excitations in qualitative agreement with the experiments. The doping-dependent bandwidth due to the strong correlation physics is the origin of the hardening effect. We also show that dispersions in the AFM regime, different from those in the paramagnetic (PM) regime, hardly vary with dopant density. These excitations are mainly collective in nature instead of particle-hole-like. We further discuss the interplay and different contributions of these two kinds of excitations in the PM phase and show that the dominance of the collective excitation increases with decreasing dopant concentrations

    PHYSIOLOGICAL AND ELECTROMYOGRAPHIC RESPONSES AT THREE LEVELS OF BICYCLE SEAT HEIGHT

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    Recently, bicycle riding has become one of the most popular exercises. As the use time increased, the risk of pedalling injury raised. Holmes (1994) indicated that inappropriate bicycle saddle height could result in lower limbs injuries. The motivation of this study was to find out the best riding position that could effectively use energy from the physiology and electromyography measures. The oxygen consumption (VO2), heart rate (HR), respiratory exchange ratio (RER) and the muscle activity (electromyography, EMG) from rectus femoris (RF) and biceps femoris (BF) of lower limb were collected during a 6 min cycling trail in three different heights of bicycle saddle. The purpose of this study was to compare the effects of three different types of bicycle seat heights and different perspectives of muscle activity and physiology’s parameters

    To Enhance the Fire Resistance Performance of High-Speed Steel Roller Door with Water Film System

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    The structure of high-speed roller door with water film has improved in this study. The flameproof water film system is equipped with a water circulating device to reduce the water consumption of water film system. The water film is generated at the roller box of the high-speed roller door in this study. The heating test is done with the full-scale heating furnace. Both cases of the water film on unexposed surface and water film on exposed surface passed the fire resistance test based on ISO 834, proving that the high-speed roller door with water film system has 120A fire resistance period. The main findings indicate that the water film on exposed surface shows that as the amount of water film evaporated by high temperature inside the furnace must be greater than the evaporation capacity of water film on unexposed surface, the required water supply is 660 L more than the water film on unexposed surface

    Forward Genetic Dissection of Biofilm Development by Fusobacterium nucleatum: Novel Functions of Cell Division Proteins FtsX and EnvC.

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    Fusobacterium nucleatum is a key member of the human oral biofilm. It is also implicated in preterm birth and colorectal cancer. To facilitate basic studies of fusobacterial virulence, we describe here a versatile transposon mutagenesis procedure and a pilot screen for mutants defective in biofilm formation. Out of 10 independent biofilm-defective mutants isolated, the affected genes included the homologs of the Escherichia coli cell division proteins FtsX and EnvC, the electron transport protein RnfA, and four proteins with unknown functions. Next, a facile new gene deletion method demonstrated that nonpolar, in-frame deletion of ftsX or envC produces viable bacteria that are highly filamentous due to defective cell division. Transmission electron and cryo-electron microscopy revealed that the ΔftsX and ΔenvC mutant cells remain joined with apparent constriction, and scanning electron microscopy (EM) uncovered a smooth cell surface without the microfolds present in wild-type cells. FtsX and EnvC proteins interact with each other as well as a common set of interacting partners, many with unknown function. Last, biofilm development is altered when cell division is blocked by MinC overproduction; however, unlike the phenotypes of ΔftsX and ΔenvC mutants, a weakly adherent biofilm is formed, and the wild-type rugged cell surface is maintained. Therefore, FtsX and EnvC may perform novel functions in Fusobacterium cell biology. This is the first report of an unbiased approach to uncover genetic determinants of fusobacterial biofilm development. It points to an intriguing link among cytokinesis, cell surface dynamics, and biofilm formation, whose molecular underpinnings remain to be elucidated.IMPORTANCE Little is known about the virulence mechanisms and associated factors in F. nucleatum, due mainly to the lack of convenient genetic tools for this organism. We employed two efficient genetic strategies to identify F. nucleatum biofilm-defective mutants, revealing FtsX and EnvC among seven biofilm-associated factors. Electron microscopy established cell division defects of the ΔftsX and ΔenvC mutants, accompanied with a smooth cell surface, unlike the microfold, rugged appearance of wild-type bacteria. Proteomic studies demonstrated that FtsX and EnvC interact with each other as well as a set of common and unique interacting proteins, many with unknown functions. Importantly, blocking cell division by MinC overproduction led to formation of a weakly adherent biofilm, without alteration of the wild-type cell surface. Thus, this work links cell division and surface dynamics to biofilm development and lays a foundation for future genetic and biochemical investigations of basic cellular processes in this clinically significant pathogen
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