Keterlibatan Organ Pada Pasien Leptospirosis Di Rsup Dr Kariadi Semarang

Background: Leptospirosis is a zoonotic disease that is widespread in the world. The incidence of leptospirosis in Indonesia, especially in Semarang is still quite high and leptospirosis can cause organ involvement that can increase patient morbidity.Purpose: Measuring organ involvement in patients with leptospirosis in the Hospital Dr. Kariadi and analyze differences in organ involvement in icteric leptospirosis and anicteric leptospirosis patients.Methods: This study is a descriptive analytic. Data were taken from the case record form of clinical research data leptospirosis Hospital Dr. Kariadi. Subjects were all patients with confirmed leptospirosis, with a total of 84 patients. Diagnosis is made by MAT. Differences in liver organ involvement, kidney, lung and heart were analyzed by Fisher's Exact test, while the difference in hematologic organ involvement were analyzed by Kolmogorov Smirnof 2 samples.Results: In patients with icteric leptospirosis, organ involvement is the liver appears most 100%. In anikteric leptospirosis patients, organ involvement is the most widely kidney 76.9%. The difference between the kidney and liver organ involvement in patients with icteric leptospirosis and anikteric leptospirosis is significant with p <0.05. The difference between organ involvement lungs, heart, and hematology in patients with icteric leptospirosis and anikteric leptospirosis is not significant with p>0.05.Conclusion: There is a difference between engagement kidney and liver in icteric leptospirosis and anikteric leptospirosis patienrs. There is no difference between organ involvement pulmonary, cardiac and hematological in icteric leptospirosis and anikteric leptospirosis patients