Economic impacts of the United States of siting decisions for the international thermonuclear experimental reactor: Executive summary

This summary highlights the results of a study that examined and compared the probable short-term economic impacts of the International Thermonuclear Experimental Reactor (ITER) on the United States (U.S.) if (1) ITER were to be sited in the U.S. or (2) ITER were to be sited in one of the other countries that, along with the U.S., are currently participating in the ITER program. Life-cycle costs associated with ITER construction, operation, and decommissioning were analyzed to assess their economic impact. A number of possible U.S. {open_quotes}host{close_quotes} and U.S. {open_quotes}non-host{close_quotes} technology and cost-sharing arrangements were examined. The study examined both national and local/regional economic impacts, as measured by gross domestic product (GDP), regional output, employment, income, and net exports. These impacts represent a portion of the complex, interrelated set of economic considerations that characterize U.S. host and U.S. non-host participation in ITER

Structure of the Jovian magnetodisk current sheet] initial Galileo observations

Abstract The ten!degree tilt of the Jovian magnetic dipole causes the magnetic equator to move back and forth across Jupiter|s rotational equator and the Galileo orbit that lies therein[ Beyond about 13 Jovian radii\ the equatorial current sheet thins and the magnetic structure changes from quasi!dipolar into magnetodisk!like with two regions of nearly radial but antiparallel magnetic _eld separated by a strong current layer[ The magnetic _eld at the center of the current sheet is very weak in this region[ Herein we examine the current sheet at radial distances from 13Ð44 Jovian radii[ We _nd that the magnetic structure very much resembles the structure seen at planetary magnetopause and tail current sheet crossings There is also transient or patchy reconnection in which short duration strong nor! mal components and fast~ows are seen "Russell and Elphic\ 0867#[ Steady!state reconnection has been con! _rmed only at the terrestrial magnetopause but evidence for transient reconnection has been found at Mercury "Russell and Walker\ 0874#^Earth "Russell and Elphic\ 0867# and Jupiter "Walker and Russell\ 0874#[ Finally\ there is apparently quiescent structure along the mag! netopause normal that seems not to lead to any dynami! cal consequences[ These structured\ but apparently quiescent\ normal components are seen at magnetopause crossings throughout the solar system "Huddleston et al [\ 0886#

Structure of the Jovian magnetodisk current sheet] initial Galileo observations

Abstract The ten!degree tilt of the Jovian magnetic dipole causes the magnetic equator to move back and forth across Jupiter|s rotational equator and the Galileo orbit that lies therein[ Beyond about 13 Jovian radii\ the equatorial current sheet thins and the magnetic structure changes from quasi!dipolar into magnetodisk!like with two regions of nearly radial but antiparallel magnetic _eld separated by a strong current layer[ The magnetic _eld at the center of the current sheet is very weak in this region[ Herein we examine the current sheet at radial distances from 13Ð44 Jovian radii[ We _nd that the magnetic structure very much resembles the structure seen at planetary magnetopause and tail current sheet crossings There is also transient or patchy reconnection in which short duration strong nor! mal components and fast~ows are seen "Russell and Elphic\ 0867#[ Steady!state reconnection has been con! _rmed only at the terrestrial magnetopause but evidence for transient reconnection has been found at Mercury "Russell and Walker\ 0874#^Earth "Russell and Elphic\ 0867# and Jupiter "Walker and Russell\ 0874#[ Finally\ there is apparently quiescent structure along the mag! netopause normal that seems not to lead to any dynami! cal consequences[ These structured\ but apparently quiescent\ normal components are seen at magnetopause crossings throughout the solar system "Huddleston et al [\ 0886#

On the making and taking of professionalism in the further education workplace

This paper examines the changing nature of professional practice in English further education. At a time when neo-liberal reform has significantly impacted on this under-researched and over-market-tested sector, little is known about who its practitioners are and how they construct meaning in their work. Sociological interest in the field has tended to focus on further education practitioners as either the subjects of market and managerial reform or as creative agents operating within the contradictions of audit and inspection cultures. In challenging such dualism, which is reflective of wider sociological thinking, the paper examines the ways in which agency and structure combine to produce a more transformative conception of the further education professional. The approach contrasts with a prevailing policy discourse that seeks to re-professionalise and modernise further education practice without interrogating either the terms of its professionalism or the neo-liberal practices in which it resides

Photobiomodulation preserves mitochondrial redox state and is retinoprotective in a rodent model of retinitis pigmentosa

Photobiomodulation (PBM) by far-red (FR) to near-infrared (NIR) light has been demonstrated to restore the function of damaged mitochondria, increase the production of cytoprotective factors and prevent cell death. Our laboratory has shown that FR PBM improves functional and structural outcomes in animal models of retinal injury and retinal degenerative disease. The current study tested the hypothesis that a brief course of NIR (830 nm) PBM would preserve mitochondrial metabolic state and attenuate photoreceptor loss in a model of retinitis pigmentosa, the P23H transgenic rat. P23H rat pups were treated with 830 nm light (180 s; 25 mW/cm2; 4.5 J/cm2) using a light-emitting diode array (Quantum Devices, Barneveld, WI) from postnatal day (p) 10 to p25. Sham-treated rats were restrained, but not treated with 830 nm light. Retinal metabolic state, function and morphology were assessed at p30 by measurement of mitochondrial redox (NADH/FAD) state by 3D optical cryo-imaging, electroretinography (ERG), spectral-domain optical coherence tomography (SD-OCT), and histomorphometry. PBM preserved retinal metabolic state, retinal function, and retinal morphology in PBM-treated animals compared to the sham-treated group. PBM protected against the disruption of the oxidation state of the mitochondrial respiratory chain observed in sham-treated animals. Scotopic ERG responses over a range of flash intensities were significantly greater in PBM-treated rats compared to sham controls. SD-OCT studies and histological assessment showed that PBM preserved the structural integrity of the retina. These findings demonstrate for the first time a direct effect of NIR PBM on retinal mitochondrial redox status in a well-established model of retinal disease. They show that chronic proteotoxic stress disrupts retinal bioenergetics resulting in mitochondrial dysfunction, and retinal degeneration and that therapies normalizing mitochondrial metabolism have considerable potential for the treatment of retinal degenerative disease

Gangs and guilt: Towards a new theory of horror film

The most basic and unanimous statement made in scholarship on horror films is that horror films are ‘about’ fear: the primary purpose of horror films is to scare viewers. Based on horror films from the 1970s until the present in which child gangs play a significant part, this essay advances a new theory of horror film, namely that horror films primarily seek to elicit not fear but guilt. The analysis focuses on four topics: themes, camera angles, horror’s cinematic casting of ‘abnormality,’ and the rift, unique to the horror genre, between audience ‘alignment’ and ‘allegiance.

Different patterns of labour market integration by migration motivation in Europe: the role of host country human capital

We study whether individual decisions to invest in the host country, namely obtaining equivalent qualifications, improving language skills, or naturalisation explain differences in labour market integration between migrants depending on their initial motivation. We use cross-national European data from the 2008 ad-hoc module of the Labour Force Survey to analyse migrant gaps in labour market participation, employment, occupational status and precarious employment. We find that different rates of and returns to host country human capital explain a substantial part of the improvements in labour market outcomes with years of residence, particularly for non-economic migrants who experience faster growth on average

Mobile Consumer Behavior in Fashion m-Retail: An Eye Tracking Study to Understand Gender Differences

© 2020 ACM. With exponential adoption of mobile devices, consumers increasingly use them for shopping. There is a need to understand the gender differences in mobile consumer behavior. This study used mobile eye tracking technology and mixed-method approach to analyze and compare how male and female mobile fashion consumers browse and shop on smartphones. Mobile eye tracking glasses recorded fashion consumers' shopping experiences using smartphones for browsing and shopping on the actual fashion retailer's website. 14 participants successfully completed this study, half of them were males and half females. Two different data analysis approaches were employed, namely a novel framework of the shopping journey, and semantic gaze mapping with 31 Areas of Interest (AOI) representing the elements of the shopping journey. The results showed that male and female users exhibited significantly different behavior patterns, which have implications for mobile website design and fashion m-retail. The shopping journey map framework proves useful for further application in market research

Complete Haplotype Sequence of the Human Immunoglobulin Heavy-Chain Variable, Diversity, and Joining Genes and Characterization of Allelic and Copy-Number Variation

The immunoglobulin heavy-chain locus (IGH) encodes variable (IGHV), diversity (IGHD), joining (IGHJ), and constant (IGHC) genes and is responsible for antibody heavy-chain biosynthesis, which is vital to the adaptive immune response. Programmed V-(D)-J somatic rearrangement and the complex duplicated nature of the locus have impeded attempts to reconcile its genomic organization based on traditional B-lymphocyte derived genetic material. As a result, sequence descriptions of germline variation within IGHV are lacking, haplotype inference using traditional linkage disequilibrium methods has been difficult, and the human genome reference assembly is missing several expressed IGHV genes. By using a hydatidiform mole BAC clone resource, we present the most complete haplotype of IGHV, IGHD, and IGHJ gene regions derived from a single chromosome, representing an alternate assembly of ∼1 Mbp of high-quality finished sequence. From this we add 101 kbp of previously uncharacterized sequence, including functional IGHV genes, and characterize four large germline copy-number variants (CNVs). In addition to this germline reference, we identify and characterize eight CNV-containing haplotypes from a panel of nine diploid genomes of diverse ethnic origin, discovering previously unmapped IGHV genes and an additional 121 kbp of insertion sequence. We genotype four of these CNVs by using PCR in 425 individuals from nine human populations. We find that all four are highly polymorphic and show considerable evidence of stratification (Fst = 0.3–0.5), with the greatest differences observed between African and Asian populations. These CNVs exhibit weak linkage disequilibrium with SNPs from two commercial arrays in most of the populations tested