Multiphase modelling of vascular tumour growth in two spatial dimensions

In this paper we present a continuum mathematical model of vascular tumour growth which is based on a multiphase framework in which the tissue is decomposed into four distinct phases and the principles of conservation of mass and momentum are applied to the normal/healthy cells, tumour cells, blood vessels and extracellular material. The inclusion of a diffusible nutrient, supplied by the blood vessels, allows the vasculature to have a nonlocal influence on the other phases. Two-dimensional computational simulations are carried out on unstructured, triangular meshes to allow a natural treatment of irregular geometries, and the tumour boundary is captured as a diffuse interface on this mesh, thereby obviating the need to explicitly track the (potentially highly irregular and ill-defined) tumour boundary. A hybrid finite volume/finite element algorithm is used to discretise the continuum model: the application of a conservative, upwind, finite volume scheme to the hyperbolic mass balance equations and a finite element scheme with a stable element pair to the generalised Stokes equations derived from momentum balance, leads to a robust algorithm which does not use any form of artificial stabilisation. The use of a matrix-free Newton iteration with a finite element scheme for the nutrient reaction-diffusion equations allows full nonlinearity in the source terms of the mathematical model. Numerical simulations reveal that this four-phase model reproduces the characteristic pattern of tumour growth in which a necrotic core forms behind an expanding rim of well-vascularised proliferating tumour cells. The simulations consistently predict linear tumour growth rates. The dependence of both the speed with which the tumour grows and the irregularity of the invading tumour front on the model parameters are investigated

Cumulant expansion of the periodic Anderson model in infinite dimension

The diagrammatic cumulant expansion for the periodic Anderson model with infinite Coulomb repulsion ($U=\infty$) is considered here for an hypercubic lattice of infinite dimension ($d=\infty$). The same type of simplifications obtained by Metzner for the cumulant expansion of the Hubbard model in the limit of $d=\infty$, are shown to be also valid for the periodic Anderson model.Comment: 13 pages, 7 figures.ps. To be published in J. Phys. A: Mathematical and General (1997

Many-body approach to the nonlinear interaction of charged particles with an interacting free electron gas

We report various many-body theoretical approaches to the nonlinear decay rate and energy loss of charged particles moving in an interacting free electron gas. These include perturbative formulations of the scattering matrix, the self-energy, and the induced electron density. Explicit expressions for these quantities are obtained, with inclusion of exchange and correlation effects.Comment: 11 pages, 5 figures. To appear in Journal of Physics

Fractional Aharonov-Bohm effect in mesoscopic rings

We study the effects of correlations on a one dimensional ring threaded by a uniform magnetic flux. In order to describe the interaction between particles, we work in the framework of the U $\infty$ Hubbard and $t$-$J$ models. We focus on the dilute limit. Our results suggest the posibility that the persistent current has an anomalous periodicity $\phi_{0}/p$, where $p$ is an integer in the range $2\leq p\leq N_{e}$ ($N_{e}$ is the number of particles in the ring and $\phi_{0}$ is the flux quantum). We found that this result depends neither on disorder nor on the detailed form of the interaction, while remains the on site infinite repulsion.Comment: 14 pages (Revtex), 5 postscript figures. Send e-mail to: [email protected]

Variational cluster approach to correlated electron systems in low dimensions

A self-energy-functional approach is applied to construct cluster approximations for correlated lattice models. It turns out that the cluster-perturbation theory (Senechal et al, PRL 84, 522 (2000)) and the cellular dynamical mean-field theory (Kotliar et al, PRL 87, 186401 (2001)) are limiting cases of a more general cluster method. Results for the one-dimensional Hubbard model are discussed with regard to boundary conditions, bath degrees of freedom and cluster size.Comment: 4 pages, final version with minor change

Slow-string limit and "antiferromagnetic" state in AdS/CFT

We discuss a slow-moving limit of a rigid circular equal-spin solution on R x S^3. We suggest that the solution with the winding number equal to the total spin approximates the quantum string state dual to the maximal-dimension ``antiferromagnetic'' state of the SU(2) spin chain on the gauge theory side. An expansion of the string action near this solution leads to a weakly coupled system of a sine-Gordon model and a free field. We show that a similar effective Hamiltonian appears in a certain continuum limit from the half-filled Hubbard model that was recently suggested to describe the all-order dilatation operator of the dual gauge theory in the SU(2) sector. We also discuss some other slow-string solutions with one spin component in AdS_5 and one in S^5.Comment: 32 pages, Latex v2: one footnote and references adde

Strong-Coupling Expansion for the Hubbard Model

A strong-coupling expansion for models of correlated electrons in any dimension is presented. The method is applied to the Hubbard model in $d$ dimensions and compared with numerical results in $d=1$. Third order expansion of the Green function suffices to exhibit both the Mott metal-insulator transition and a low-temperature regime where antiferromagnetic correlations are strong. It is predicted that some of the weak photoemission signals observed in one-dimensional systems such as $SrCuO_2$ should become stronger as temperature increases away from the spin-charge separated state.Comment: 4 pages, RevTex, 3 epsf figures include

Cluster coherent potential approximation for electronic structure of disordered alloys

We extend the single-site coherent potential approximation (CPA) to include the effects of non-local disorder correlations (alloy short-range order) on the electronic structure of random alloy systems. This is achieved by mapping the original Anderson disorder problem to that of a selfconsistently embedded cluster. This cluster problem is then solved using the equations of motion technique. The CPA is recovered for cluster size $N_{c}=1$, and the disorder averaged density-of-states (DOS) is always positive definite. Various new features, compared to those observed in CPA, and related to repeated scattering on pairs of sites, reflecting the effect of SRO are clearly visible in the DOS. It is explicitly shown that the cluster-CPA method always yields positive-definite DOS. Anderson localization effects have been investigated within this approach. In general, we find that Anderson localization sets in before band splitting occurs, and that increasing partial order drives a continuous transition from an Anderson insulator to an incoherent metal.Comment: 7 pages, 6 figures. submitted to PR

A Velocity-based Moving Mesh Virtual Element Method

We present a velocity-based moving mesh virtual element method for the numerical solution of PDEs involving moving boundaries. The virtual element method is used for computing both the mesh velocity and a conservative Arbitrary Lagrangian-Eulerian solution transfer on general polygonal meshes. The approach extends the linear finite element method to polygonal mesh structures, achieving the same degree of accuracy. In the context of moving meshes, a major advantage of the virtual element approach is the ease with which nodes can be inserted on mesh edges. Demonstrations of node insertion techniques are presented to show that moving polygonal meshes can be simply adapted for situations where a boundary encounters a solid object or another moving boundary, without reduction in degree of accuracy

Climate or rural development policy?

Being heavily energy dependent, it is not much of a surprise that Europe pays special attention to reducing the use of fossil fuels. Each one of the ten new member states is characterized by relatively low per capita energy consumption and relatively low energy efficiency, and the share of renewables in their energy mix tends to be low, too. The paper examines the problem when policy measures create a decrease in environmental capital instead of an increase. In this case it hardly seems justified to talk about environmental protection. The authors describe a case of a Hungarian rapeseed oil mill which would not be of too much interest on its own but given that almost all similar plants went bankrupt, there are some important lessons to learn from its survival. The enterprise the authors examined aimed at establishing a micro-regional network. They completed a brown-field development to establish a small plant on the premises of a former large agricultural cooperative. By partnering with the former employees and suppliers of the sometime cooperative, they enjoyed some benefits which all the other green-field businesses focusing on fuel production could not. The project improved food security, energy security and population retention as well