4,140 research outputs found
RFID-enabled real-time manufacturing for automotive part and accessory suppliers
Automotive part and accessory manufacturers (APAMs) at the lower tiers of the automotive vertical have been following leading vehicle assemblers in adopting RFID (Radio Frequency Identification) and ubiquitous computing technologies, aiming to alleviate their advanced manufacturing systems. RFID-enabled real-time traceability and visibility facilitate the implementation of advanced strategies such as Just-In-Time (JIT) lean / responsive manufacturing and mass customization (MC). Being typically small and medium sized, however, APAMs are faced up with business and technical challenges which are summarized by the so-called "three high problems". They are high cost, high risk and high level of requirement for technical skills. Based on a series of industrial field studies, this paper establishes an innovative service-oriented business model for overcoming the "three high Problems" based on the concept of Product Service Systems (PSS) and RFID gateway technology.published_or_final_versionThe 40th International Conference on Computers and Industrial Engineering (CIE 2010), Awaji, Japan, 25-28 July 2010. In Proceedings of CIE40, 2010, p. 1-
Naming Objects in BIM: A Convention and a Semiautomatic Approach
A consistent and easily recognizable name is the primary identifier of an object in building information modeling (BIM). Existing naming conventions vary significantly and require extensive manual work that is often tedious and error-prone. This study (1) develops a standardized naming convention for BIM objects and (2) devises a semiautomatic naming approach for saving manual work. In the proposed naming convention, each segment is included by referencing BIM standards with a consideration of BIM users’ actual needs, and the semiautomatic approach is formalized for both completed and ongoing BIM models. Validated by a control experiment and feedback from the project manager and BIM engineers of a real-life project, this research can be immediately applied to realize standardized BIM object names. This study also generates practical implications for BIM-based project management, where standardized BIM object names are required for supporting object identification and information incorporation throughout a project lifecycle. - See more at: http://ascelibrary.org/doi/10.1061/%28ASCE%29CO.1943-7862.0001314#sthash.XOoOaKep.dpufpostprin
On the force field optimisation of β -lactam cores using the force field Toolkit
When employing molecular dynamics (MD) simulations for computer-aided drug design, the quality of the used force fields is highly important. Here we present reparametrisations of the force fields for the core molecules from 9 different β-lactam classes, for which we utilized the force field Toolkit and Gaussian calculations. We focus on the parametrisation of the dihedral angles, with the goal of reproducing the optimised quantum geometry in MD simulations. Parameters taken from CGenFF turn out to be a good initial guess for the multiplicity of each dihedral angle, but the key to a successful parametrisation is found to lie in the phase shifts. Based on the optimised quantum geometry, we come up with a strategy for predicting the phase shifts prior to the dihedral potential fitting. This allows us to successfully parameterise 8 out of the 11 molecules studied here, while the remaining 3 molecules can also be parameterised with small adjustments. Our work highlights the importance of predicting the dihedral phase shifts in the ligand parametrisation protocol, and provides a simple yet valuable strategy for improving the process of parameterising force fields of drug-like molecules
A case of implementing RFID-based real-time shop-floor material management for household electrical appliance manufacturers
Radio Frequency Identification (RFID) technologies provide automatic and accurate object data capturing capability and enable real-time object visibility and traceability. Potential benefits have been widely reported for improving manufacturing shop-floor management. However, reports on how such potentials come true in real-life shop-floor daily operations are very limited. As a result, skeptics overwhelm enthusiasm. This paper contributes to the re-vitalization of RFID efforts in manufacturing industries by presenting a real-life case study of applying RFID for managing material distribution in a complex assembly shop-floor at a large air conditioner manufacturer. The case study discusses how technical, social and organizational issues have been addressed throughout the project within the company. It is hoped that insights and lessons gained be generalized for future efforts across household electrical appliance manufacturers that share similar shop-floor. © 2010 The Author(s).published_or_final_versionSpringer Open Choice, 21 Feb 201
Dirac operators and the Very Strange Formula for Lie superalgebras
Using a super-affine version of Kostant's cubic Dirac operator, we prove a
very strange formula for quadratic finite-dimensional Lie superalgebras with a
reductive even subalgebra.Comment: Latex file, 25 pages. A few misprints corrected. To appear in the
forthcoming volume "Advances in Lie Superalgebras", Springer INdAM Serie
Establishing production service system and information collaboration platform for mold and die products
This paper investigates how the new concept of product service systems can be used and extended to transform, elevate, and revitalize traditional equipment manufacturing industry such as the Mold and Die (MD) sector. A mold and die production service systems (MPSS) framework is established based on recent developments within our industrial collaborators. Within the MPSS framework, MD manufacturers become more specialized in producing MD products and components while sharing and outsourcing manufacturing-oriented services (MOS) from a service provider. Typical services include collaborative order pooling and release, collaborative project progress status tracking, contractor-managed collaborative outsourcing, collaborative product design, collaborative production planning and scheduling, and after-sales technical supports. MOSs are designed, developed, and deployed as SaaS (software as application services) following the service-oriented architecture. Collectively, they form iMPSS-an Information and Collaboration Platform that enables MPSS. The use of iMPSS leads to benefits for stakeholders involved in providing mold and die functionality including better shopfloor decisions and reduced IT investments. © 2010 The Author(s).published_or_final_versionSpringer Open Choice, 21 Feb 201
Deformation of the Fermi surface in the extended Hubbard model
The deformation of the Fermi surface induced by Coulomb interactions is
investigated in the t-t'-Hubbard model. The interplay of the local U and
extended V interactions is analyzed. It is found that exchange interactions V
enhance small anisotropies producing deformations of the Fermi surface which
break the point group symmetry of the square lattice at the Van Hove filling.
This Pomeranchuck instability competes with ferromagnetism and is suppressed at
a critical value of U(V). The interaction V renormalizes the t' parameter to
smaller values what favours nesting. It also induces changes on the topology of
the Fermi surface which can go from hole to electron-like what may explain
recent ARPES experiments.Comment: 5 pages, 4 ps figure
Spin-enhanced nanodiamond biosensing for ultrasensitive diagnostics
The quantum spin properties of nitrogen-vacancy defects in diamond enable diverse applications in quantum computing and communications. However, fluorescent nanodiamonds also have attractive properties for in vitro biosensing, including brightness, low cost and selective manipulation of their emission. Nanoparticle-based biosensors are essential for the early detection of disease, but they often lack the required sensitivity. Here we investigate fluorescent nanodiamonds as an ultrasensitive label for in vitro diagnostics, using a microwave field to modulate emission intensity and frequency-domain analysis to separate the signal from background autofluorescence, which typically limits sensitivity. Focusing on the widely used, low-cost lateral flow format as an exemplar, we achieve a detection limit of 8.2 × 10−19 molar for a biotin–avidin model, 105 times more sensitive than that obtained using gold nanoparticles. Single-copy detection of HIV-1 RNA can be achieved with the addition of a 10-minute isothermal amplification step, and is further demonstrated using a clinical plasma sample with an extraction step. This ultrasensitive quantum diagnostics platform is applicable to numerous diagnostic test formats and diseases, and has the potential to transform early diagnosis of disease for the benefit of patients and populations
Expanding genotype/phenotype of neuromuscular diseases by comprehensive target capture/NGS
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