113,038 research outputs found
Assessment of closure coefficients for compressible-flow turbulence models
A critical assessment is made of the closure coefficients used for turbulence length scale in existing models of the transport equation, with reference to the extension of these models to compressible flow. It is shown that to satisfy the compressible 'law of the wall', the model coefficients must actually be functions of density gradients. The magnitude of the errors that result from neglecting this dependence on density varies with the variable used to specify the length scale. Among the models investigated, the k-omega model yields the best performance, although it is not completely free from errors associated with density terms. Models designed to reduce the density-gradient effect to an insignificant level are proposed
Pion Form Factor in the Factorization Formalism
Based on the light-cone (LC) framework and the factorization formalism,
the transverse momentum effects and the different helicity components'
contributions to the pion form factor are recalculated. In
particular, the contribution to the pion form factor from the higher helicity
components (), which come from the spin-space Wigner
rotation, are analyzed in the soft and hard energy regions respectively. Our
results show that the right power behavior of the hard contribution from the
higher helicity components can only be obtained by fully keeping the
dependence in the hard amplitude, and that the dependence in LC wave
function affects the hard and soft contributions substantially. As an example,
we employ a model LC wave function to calculate the pion form factor and then
compare the numerical predictions with the experimental data. It is shown that
the soft contribution is less important at the intermediate energy region.Comment: 21 pages, 4 figure
Information on the Pion Distribution Amplitude from the Pion-Photon Transition Form Factor with the Belle and BaBar Data
The pion-photon transition form factor (TFF) provides strong constraints on
the pion distribution amplitude (DA). We perform an analysis of all existing
data (CELLO, CLEO, BaBar, Belle) on the pion-photon TFF by means of light-cone
pQCD approach in which we include the next-to-leading order correction to the
valence-quark contribution and estimate the non-valence-quark contribution by a
phenomenological model based on the TFF's limiting behavior at both
and . At present, the pion DA is not definitely determined, it is
helpful to have a pion DA model that can mimic all the suggested behaviors,
especially to agree with the constraints from the pion-photon TFF in whole
measured region within a consistent way. For the purpose, we adopt the
conventional model for pion wavefunction/DA that has been constructed in our
previous paper \cite{hw1}, whose broadness is controlled by a parameter . We
fix the DA parameters by using the CELLO, CLEO, BABAR and Belle data within the
smaller region ( GeV), where all the data are consistent
with each other. And then the pion-photon TFF is extrapolated into larger
region. We observe that the BABAR favors which has the behavior close
to the Chernyak-Zhitnitsky DA, whereas the recent Belle favors which
is close to the asymptotic DA. We need more accurate data at large region
to determine the precise value of , and the definite behavior of pion DA can
be concluded finally by the consistent data in the coming future.Comment: 6 pages, 5 figures. Slightly changed and references update
An Implication of "Gravity as the Weakest Force"
The negative specific heat of a radiating black hole is indicative of a
cataclysmic endpoint to the evaporation process. In this letter, we suggest a
simple mechanism for circumventing such a dramatic outcome. The basis for our
argument is a conjecture that was recently proposed by Arkani-Hamed and
collaborators. To put it another way, we use their notion of ``Gravity as the
Weakest Force'' as a means of inhibiting the process of black hole evaporation.Comment: 7 pages; v2 some discussion clarifie
Gamma-Ray Burst Afterglows from Realistic Fireballs
A GRB afterglow has been commonly thought to be due to continuous
deceleration of a postburst fireball. Many analytical models have made
simplifications for deceleration dynamics of the fireball and its radiation
property, although they are successful at explaining the overall features of
the observed afterglows. We here propose a model for a GRB afterglow in which
the evolution of a postburst fireball is in an intermediate case between the
adiabatic and highly radiative expansion. In our model, the afterglow is both
due to the contribution of the adiabatic electrons behind the external
blastwave of the fireball and due to the contribution of the radiative
electrons. In addition, this model can describe evolution of the fireball from
the extremely relativistic phase to the non-relativistic phase. Our
calculations show that the fireball will go to the adiabatic expansion phase
after about a day if the accelerated electrons are assumed to occupy the total
internal energy. In all cases considered, the fireball will go to the mildly
relativistic phase about seconds later, and to the non-relativistic
phase after several days. These results imply that the relativistic adiabatic
model cannot describe the deceleration dynamics of the several-days-later
fireball. The comparison of the calculated light curves with the observed
results at late times may imply the presence of impulsive events or energy
injection with much longer durations.Comment: 18 pages, 10 figures, plain latex file, submitted to Ap
An assessment and application of turbulence models for hypersonic flows
The current approach to the Accurate Computation of Complex high-speed flows is to solve the Reynolds averaged Navier-Stokes equations using finite difference methods. An integral part of this approach consists of development and applications of mathematical turbulence models which are necessary in predicting the aerothermodynamic loads on the vehicle and the performance of the propulsion plant. Computations of several high speed turbulent flows using various turbulence models are described and the models are evaluated by comparing computations with the results of experimental measurements. The cases investigated include flows over insulated and cooled flat plates with Mach numbers ranging from 2 to 8 and wall temperature ratios ranging from 0.2 to 1.0. The turbulence models investigated include zero-equation, two-equation, and Reynolds-stress transport models
TTC5 is required to prevent apoptosis of acute myeloid leukemia stem cells
Using a screening strategy, we identified the tetratricopeptide repeat (TPR) motif protein, Tetratricopeptide repeat domain 5 (TTC5, also known as stress responsive activator of p300 or Strap) as required for the survival of human acute myeloid leukemia (AML) cells. TTC5 is a stress-inducible transcription cofactor known to interact directly with the histone acetyltransferase EP300 to augment the TP53 response. Knockdown (KD) of TTC5 induced apoptosis of both murine and human AML cells, with concomitant loss of clonogenic and leukemia-initiating potential; KD of EP300 elicited a similar phenotype. Consistent with the physical interaction of TTC5 and EP300, the onset of apoptosis following KD of either gene was preceded by reduced expression of BCL2 and increased expression of pro-apoptotic genes. Forced expression of BCL2 blocked apoptosis and partially rescued the clonogenic potential of AML cells following TTC5 KD. KD of both genes also led to the accumulation of MYC, an acetylation target of EP300, and the form of MYC that accumulated exhibited relative hypoacetylation at K148 and K157, residues targeted by EP300. In view of the ability of excess cellular MYC to sensitize cells to apoptosis, our data suggest a model whereby TTC5 and EP300 cooperate to prevent excessive accumulation of MYC in AML cells and their sensitization to cell death. They further reveal a hitherto unappreciated role for TTC5 in leukemic hematopoiesis
Low Scale Non-universal, Non-anomalous U(1)'_F in a Minimal Supersymmetric Standard Model
We propose a non-universal U(1)'_F symmetry combined with the Minimal
Supersymmetric Standard Model. All anomaly cancellation conditions are
satisfied without exotic fields other than three right-handed neutrinos.
Because our model allows all three generations of chiral superfields to have
different U(1)'_F charges, upon the breaking of the U(1)'_F symmetry at a low
scale, realistic masses and mixing angles in both the quark and lepton sectors
are obtained. In our model, neutrinos are predicted to be Dirac fermions and
their mass ordering is of the inverted hierarchy type. The U(1)'_F charges of
the chiral super-fields also naturally suppress the mu term and automatically
forbid baryon number and lepton number violating operators. While all
flavor-changing neutral current constraints in the down quark and charged
lepton sectors can be satisfied, we find that constraint from D0-D0bar turns
out to be much more stringent than the constraints from the precision
electroweak data.Comment: 21 pages, 2 figures; v2: discussion on sparticle mass spectrum
included, 27 pages, 2 figure
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