A 3D ANALYSIS OF THE VOllEYBAll SPIKE

The purpose of this study was to identify and describe the biomechanical characteristics of the high school volleyball players jump spikes. Eleven elite male players participated in this study. Two Peak high-speed cameras (120 Hz) were genlocked to record the spiking action. The results showed that the spiking techniques of male high school volleyball players are quite similar to those of university volleyball players except for contact ball height. It is suggested that coaches should train the young players jumping ability and fast spiking motion in order to improve spiking power

Understanding the antecedents of consumer brand engagement by managing brand communities on social media

As social media provide companies with opportunities to create touch-points by enabling consumers to interact with brands in new ways, a key issue for organizations is how to use brand communities to engage customers and enhance their relationships with brands. Brand community interactivity is one of the latest developments to engage consumers in online brand communities. The objective of brand communities is not only to attract potential customers, but also to retain loyal consumers and gain advocates. Thus, brands and companies’ social media activity should be appropriately organized and managed for high-level consumer brand engagement (CBE), which is a comprehensive construct that allow companies to examine the bond between their brands and consumers. The essence of this CBE bond is related to the involvement of consumers, as it increases the touch-points between them and the brand. This study examined perceived interactivity as a driving factor in the context of a brand community on social media with the purpose of encouraging consumer community engagement, community satisfaction, and consumer brand engagement (CBE). Two second-order constructs were operationalized in the research model. Communication, responsiveness, and control were treated as reflective factors to create the second-order construct “perceived interactivity,” while the other second-order construct “CBE” comprised cognitive processing, affection, and activation as reflective indicators. The results, based on data collected from 328 social media users who are followers of a smartphone brand’s Facebook page, indicated that perceived interactivity is likely to significantly affect consumer community engagement and community satisfaction, which in turn foster brand engagement. Successful social media marketing practices for companies should take responsibility for transforming consumer community engagement into CBE, as it is imperative for organizations building brand communities to enhance their consumer community satisfaction through proper community management to achieve high CBE

An Enhanced Screenshot Interaction with Animated Stickers to Promote Learning Transfer

This study has implemented a platform, namely piniton.tw, rolling out a redesign of user interaction with screenshot. It is an excellent environment for students’ collaborative learning, as students upload screenshots and interact with each other to complete assignments by using animated stickers. As the study intended to investigate how to promote learning transfer by means of such enhanced screenshot interaction with animated stickers, task difficulty, online participation, and learning transfer were chosen as the basis for the research model. By applying the technology acceptance model, perceived ease of use, perceived usefulness, and behavioral intention were included. The results indicated that students’ perceived ease of use and perceived usefulness are likely to significantly affect their behavioral intention, which in turn promote learning transfer. An implication is that students’ learning transfer could be prompted greatly by enhancing their intention to use such platform that provides enhanced screenshot interaction with animated stickers

Stimulatory Effects of Androgens on Eel Primary Ovarian Development - from Phenotypes to Genotypes

Androgens stimulate primary ovarian development in Vertebrate. Japanese eels underwent operation to sample the pre- and post-treated ovarian tissues from the same individual. Ovarian phenotypic or genotypic data were mined in a pair. A correlation between the initial ovarian status (determined by kernel density estimation (KDE), presented as a probability density of oocyte size) and the consequence of androgen (17MT) treatment (change in ovary) has been showed. The initial ovarian status appeared to be important to influence ovarian androgenic sensitivity. The initial ovary was important to the outcomes of androgen treatments, and ePAV (expression presence-absence variation) is existing in Japanese eel by analyze DEGs; core, unique, or accessory genes were identified, the sensitivities of initial ovaries were correlated with their gene expression profiles. We speculated the importance of genetic differential expression on the variations of phenotypes by 17MT, and transcriptomic approach seems to allow extracting multiple layers of genomic data

The Size Stability of Alginate Beads by Different Ionic Crosslinkers

Few studies have discussed the stability of gelled alginate bead size. Therefore, the present study investigated the dynamic shrinkage of gelled alginate beads affected by two common ionic crosslinkers at different concentrations and temperatures. The results indicate that the gelled alginate beads gradually shrank with longer gelling times. The beads incubated in a Ca2+ solution shrank more dramatically than those incubated in a Ba2+ solution. Those incubated at room temperature exhibited greater shrinkage than those incubated at a low temperature. A 25% size reduction occurred in the 1% Ca2+ solution at room temperature after 300 minutes of gelling time. The alginate beads gelled took at least 120 minutes to become stable after the ionic gelation process

How Does Social Media Interactivity Affect Brand Loyalty?

As social media has become a prominent platform for networking, many organizations have begun to establish more than one brand community, as a set of supplements to their branded websites. Once most online brand interactions take place on social networking sites rather than branded sites, such customer-oriented interactions will become much more complicated and unpredictable. It is a real challenge for organizations to build successful customer-brand relationships through social networking sites. Hence, organizations that wish to enhance brand loyalty by running brand communities face the challenge of effectively conducting social customer relationship management (CRM) tactics. As social media users are susceptible to highly interactive features, understanding the nature of social media interactivity in brand communities is the key to building successful social CRM. The aim of the study is to investigate not only the effect of social media interactivity on community benefits, but also the effect of community benefits on brand loyalty. In addition to measuring the direct effects of social influence and media richness on brand loyalty, the study assessed the indirect effect of responsiveness on brand loyalty by means of community benefits, including knowledge gains and sense of membership. The results, based on data collected from 229 social media users who are followers of a Super Basketball League (SBL) team’s Facebook page, indicated that media richness had a strong, positive, and direct effect on brand loyalty, and that responsiveness had direct effects on their knowledge gains and their sense of membership, which in turn affected brand loyalty indirectly

TNFAIP3, a negative regulator of the TLR signaling pathway, is a potential predictive biomarker of response to antidepressant treatment in major depressive disorder

AbstractInflammation and abnormalities in Toll-like receptor (TLR) expression and activation have been linked to major depressive disorder (MDD). However, negative regulators of TLR pathways have not been previously investigated in this context. Here, we sought to investigate the association of depression severity, measured by the 17-item Hamilton Depression Rating Scale (HAMD-17), with mRNA expression levels of negative regulators of the TLR pathway, including SOCS1, TOLLIP, SIGIRR, MyD88s, NOD2 and TNFAIP3, in peripheral blood mononuclear cells (PBMCs) from 100 patients with MDD and 53 healthy controls, before and after treatment with antidepressants. Positive regulators of the TLR4 pathway, including Pellino 1, TRAF6 and IRAK1, were also investigated. Among all patients, MyD88s, and TNFAIP3 mRNAs were expressed at lower levels in PBMCs from patients with MDD. Multiple linear regression analyses revealed that TNFAIP3 mRNA expression before treatment was inversely correlated with severity of depression and effectively predicted improvement in HAMD-17 scores. Among 79 treatment-completers, only TNFAIP3 mRNA was significantly increased by treatment with antidepressants for 4 weeks. Treatment of human monocytes (THP-1) and mouse microglia (SIM-A9) cell lines with fluoxetine significantly increased TNFAIP3 mRNA expression and suppressed IL-6 levels. The suppressive effect of fluoxetine on IL-6 was attenuated by knockdown of TNFAIP3 expression. These findings suggest that both dysfunction of the negative regulatory system in patients with MDD and antidepressant treatment exert anti-inflammatory effects, at least in part through increased expression of the TNFAIP3 gene. They also indicate that modulating expression of the TNFAIP3 gene to rebalance TLR-mediated inflammatory signaling may be potential therapeutic strategy for treating MDD