Analysis of the Movement of Chlamydomonas Flagella: The Function of the Radial-spoke System Is Revealed by Comparison of Wild-type and Mutant Flagella

The mutation uni-1 gives rise to uniflagellate Chlamydomonas cells which rotate around a fixed point in the microscope field, so that the flagellar bending pattern can be photographed easily . This has allowed us to make a detailed analysis of the wild-type flagellar bending pattern and the bending patterns of flagella on several mutant strains. Cells containing uni-1, and recombinants of uni-1 with the suppressor mutations, sup(_pf)-1 and sup(_pf)-3, show the typical asymmetric bending pattern associated with forward swimming in Chlamydomonas, although sup(_pf)-1 flagella have about one-half the normal beat frequency, apparently as the result of defective function of the outer dynein arms. The pf-17 mutation has been shown to produce nonmotile flagella in which radial spoke heads and five characteristic axonemal polypeptides are missing. Recombinants containing pf-17 and either sup(_pf)-1 or sup(_pf)-3 have motile flagella, but still lack radial-spoke heads and the associated polypeptides . The flagellar bending pattern of these recombinants lacking radial-spoke heads is a nearly symmetric, large amplitude pattern which is quite unlike the wild-type pattern . However, the presence of an intact radial-spoke system is not required to convert active sliding into bending and is not required for bend initiation and bend propagation, since all of these processes are active in the sup(_pf) pf-17 recombinants. The function of the radial-spoke system appears to be to convert the symmetric bending pattern displayed by these recombinants into the asymmetric bending pattern required for efficient swimming, by inhibiting the development of reverse bends during the recovery phase of the bending cycle

Dirac cohomology, elliptic representations and endoscopy

The first part (Sections 1-6) of this paper is a survey of some of the recent developments in the theory of Dirac cohomology, especially the relationship of Dirac cohomology with (g,K)-cohomology and nilpotent Lie algebra cohomology; the second part (Sections 7-12) is devoted to understanding the unitary elliptic representations and endoscopic transfer by using the techniques in Dirac cohomology. A few problems and conjectures are proposed for further investigations.Comment: This paper will appear in `Representations of Reductive Groups, in Honor of 60th Birthday of David Vogan', edited by M. Nervins and P. Trapa, published by Springe

I Know Why You Went to the Clinic: Risks and Realization of HTTPS Traffic Analysis

Revelations of large scale electronic surveillance and data mining by governments and corporations have fueled increased adoption of HTTPS. We present a traffic analysis attack against over 6000 webpages spanning the HTTPS deployments of 10 widely used, industry-leading websites in areas such as healthcare, finance, legal services and streaming video. Our attack identifies individual pages in the same website with 89% accuracy, exposing personal details including medical conditions, financial and legal affairs and sexual orientation. We examine evaluation methodology and reveal accuracy variations as large as 18% caused by assumptions affecting caching and cookies. We present a novel defense reducing attack accuracy to 27% with a 9% traffic increase, and demonstrate significantly increased effectiveness of prior defenses in our evaluation context, inclusive of enabled caching, user-specific cookies and pages within the same website

Deterministic spatio-temporal control of nano-optical fields in optical antennas and nano transmission lines

We show that pulse shaping techniques can be applied to tailor the ultrafast temporal response of the strongly confined and enhanced optical near fields in the feed gap of resonant optical antennas (ROAs). Using finite-difference time-domain (FDTD) simulations followed by Fourier transformation, we obtain the impulse response of a nano structure in the frequency domain, which allows obtaining its temporal response to any arbitrary pulse shape. We apply the method to achieve deterministic optimal temporal field compression in ROAs with reduced symmetry and in a two-wire transmission line connected to a symmetric dipole antenna. The method described here will be of importance for experiments involving coherent control of field propagation in nanophotonic structures and of light-induced processes in nanometer scale volumes.Comment: 5 pages, 5 figure

Segue Between Favorable and Unfavorable Solvation

Solvation of small and large clusters are studied by simulation, considering a range of solvent-solute attractive energy strengths. Over a wide range of conditions, both for solvation in the Lennard-Jones liquid and in the SPC model of water, it is shown that the mean solvent density varies linearly with changes in solvent-solute adhesion or attractive energy strength. This behavior is understood from the perspective of Weeks' theory of solvation [Ann. Rev. Phys. Chem. 2002, 53, 533] and supports theories based upon that perspective.Comment: 8 pages, 7 figure

Resonant elastic soft x-ray scattering in oxygen-ordered YBa_2Cu_3O_{6+delta}

Static charge-density wave (CDW) and spin-density wave (SDW) order has been convincingly observed in La-based cuprates for some time. However, more recently it has been suggested by quantum oscillation, transport and thermodynamic measurements that density wave order is generic to underdoped cuprates and plays a significant role in YBa_2Cu_3O_{6+delta} (YBCO). We use resonant soft x-ray scattering at the Cu L and O K edges to search for evidence of density wave order in Ortho-II and Ortho-VIII oxygen-ordered YBCO. We report a null result -- no evidence for static CDW order -- in both Ortho-II and Ortho-VIII ordered YBCO. While this does not rule out static CDW order in the CuO_2 planes of YBCO, these measurements place limits on the parameter space (temperature, magnetic field, scattering vector) in which static CDW order may exist. In addition, we present a detailed analysis of the energy and polarization dependence of the Ortho-II superstructure Bragg reflection [0.5 0 0] at the Cu L edge. The intensity of this peak, which is due to the valence modulations of Cu in the chain layer, is compared with calculations using atomic scattering form factors deduced from x-ray absorption measurements. The calculated energy and polarization dependence of the scattering intensity is shown to agree very well with the measurement, validating the approach and providing a framework for analyzing future resonant soft x-ray scattering measurements.Comment: 11 pages, 9 figure

Magneto-controlled nonlinear optical materials

We exploit theoretically a magneto-controlled nonlinear optical material which contains ferromagnetic nanoparticles with a non-magnetic metallic nonlinear shell in a host fluid. Such an optical material can have anisotropic linear and nonlinear optical properties and a giant enhancement of nonlinearity, as well as an attractive figure of merit.Comment: 11 pages, 2 figures. To be published in Appl. Phys. Let