SE-shapelets: Semi-supervised Clustering of Time Series Using Representative Shapelets

Shapelets that discriminate time series using local features (subsequences) are promising for time series clustering. Existing time series clustering methods may fail to capture representative shapelets because they discover shapelets from a large pool of uninformative subsequences, and thus result in low clustering accuracy. This paper proposes a Semi-supervised Clustering of Time Series Using Representative Shapelets (SE-Shapelets) method, which utilizes a small number of labeled and propagated pseudo-labeled time series to help discover representative shapelets, thereby improving the clustering accuracy. In SE-Shapelets, we propose two techniques to discover representative shapelets for the effective clustering of time series. 1) A \textit{salient subsequence chain} ($SSC$) that can extract salient subsequences (as candidate shapelets) of a labeled/pseudo-labeled time series, which helps remove massive uninformative subsequences from the pool. 2) A \textit{linear discriminant selection} ($LDS$) algorithm to identify shapelets that can capture representative local features of time series in different classes, for convenient clustering. Experiments on UCR time series datasets demonstrate that SE-shapelets discovers representative shapelets and achieves higher clustering accuracy than counterpart semi-supervised time series clustering methods

Intrinsic Alignment in redMaPPer clusters -- II. Radial alignment of satellites toward cluster centers

We study the orientations of satellite galaxies in redMaPPer clusters constructed from the Sloan Digital Sky Survey at $0.1<z<0.35$ to determine whether there is any preferential tendency for satellites to point radially toward cluster centers. We analyze the satellite alignment (SA) signal based on three shape measurement methods (re-Gaussianization, de Vaucouleurs, and isophotal shapes), which trace galaxy light profiles at different radii. The measured SA signal depends on these shape measurement methods. We detect the strongest SA signal in isophotal shapes, followed by de Vaucouleurs shapes. While no net SA signal is detected using re-Gaussianization shapes across the entire sample, the observed SA signal reaches a statistically significant level when limiting to a subsample of higher luminosity satellites. We further investigate the impact of noise, systematics, and real physical isophotal twisting effects in the comparison between the SA signal detected via different shape measurement methods. Unlike previous studies, which only consider the dependence of SA on a few parameters, here we explore a total of 17 galaxy and cluster properties, using a statistical model averaging technique to naturally account for parameter correlations and identify significant SA predictors. We find that the measured SA signal is strongest for satellites with the following characteristics: higher luminosity, smaller distance to the cluster center, rounder in shape, higher bulge fraction, and distributed preferentially along the major axis directions of their centrals. Finally, we provide physical explanations for the identified dependences, and discuss the connection to theories of SA.Comment: 25 pages, 16 figures, 7 tables, accepted to MNRAS. Main statistical analysis tool changed, with the results remain simila

Inhibitory Effects of Resveratrol on PDGF-BB-Induced Retinal Pigment Epithelial Cell Migration via PDGFRβ, PI3K/Akt and MAPK Pathways

Purpose: In diseases such as proliferative vitreoretinopathy (PVR), proliferative diabetic retinopathy, and age-related macular degeneration, retinal pigment epithelial (RPE) cells proliferate and migrate. Moreover, platelet-derived growth factor (PDGF) has been shown to enhance proliferation and migration of RPE cells in PVR. Even resveratrol can suppress the migration and adhesion of many cell types, its effects on RPE cell migration and adhesion remain unknown. In this study, we investigated the inhibitory effects of resveratrol on RPE cell migration induced by PDGF-BB, an isoform of PDGF, and adhesion to fibronectin, a major ECM component of PVR tissue. Methods: The migration of RPE cells was assessed by an electric cell-substrate impedance sensing migration assay and a Transwell migration assay. A cell viability assay was used to determine the viability of resveratrol treated-cells. The cell adhesion to fibronectin was examined by an adhesion assay. The interactions of resveratrol with PDGF-BB were analyzed by a dot binding assay. The PDGF-BB-induced signaling pathways were determined by western blotting and scratch wound healing assay. Results: Resveratrol inhibited PDGF-BB-induced RPE cell migration in a dose-dependent manner, but showed no effects on ARPE19 cell adhesion to fibronectin. The cell viability assay showed no cytotoxicity of resveratrol on RPE cells and the dot binding assay revealed no direct interactions of resveratrol with PDGF-BB. Inhibitory effects of resveratrol on PDGF-BB-induced platelet-derived growth factor receptor β (PDGFRβ) and tyrosine phosphorylation and the underlying pathways of PI3K/Akt, ERK and p38 activation were found; however, resveratrol and PDGF-BB showed no effects on PDGFRα and JNK activation. Scratch wound healing assay demonstrated resveratrol and the specific inhibitors of PDGFR, PI3K, MEK or p38 suppressed PDGF-BB-induced cell migration. Conclusions: These results indicate that resveratrol is an effective inhibitor of PDGF-BB-induced RPE cell migration via PDGFRβ, PI3K/Akt and MAPK pathways, but has no effects on the RPE cell adhesion to fibronectin

Using Hybrid Angle/Distance Information for Distributed Topology Control in Vehicular Sensor Networks

In a vehicular sensor network (VSN), the key design issue is how to organize vehicles effectively, such that the local network topology can be stabilized quickly. In this work, each vehicle with on-board sensors can be considered as a local controller associated with a group of communication members. In order to balance the load among the nodes and govern the local topology change, a group formation scheme using localized criteria is implemented. The proposed distributed topology control method focuses on reducing the rate of group member change and avoiding the unnecessary information exchange. Two major phases are sequentially applied to choose the group members of each vehicle using hybrid angle/distance information. The operation of Phase I is based on the concept of the cone-based method, which can select the desired vehicles quickly. Afterwards, the proposed time-slot method is further applied to stabilize the network topology. Given the network structure in Phase I, a routing scheme is presented in Phase II. The network behaviors are explored through simulation and analysis in a variety of scenarios. The results show that the proposed mechanism is a scalable and effective control framework for VSNs

A SMIL-Based Catalog Presentation System in Electronic Commerce

Web-based catalog presentations play the key-enabling role in E-commerce in recent years. Existing catalog systems often acquire proprietary platforms, cannot deal with TV-like media objects, or consume network bandwidth inefficiently. With the emergence of advanced technologies of Web and multimedia, such hurdles can be removed. The Synchronized Multimedia Integration Language (SMIL), proposed by W3C allows Web designers to design complicated and vivid multimedia presentations in a declarative manner. These presentations are then rendered on a general-purpose browser by a SMIL player. Since the SMIL specification is quite new to the Internet and E-commerce societies, the functionality and applications of players is limited. In this paper, we propose a novel architecture based on Java JMF technology for tackling with such constraints. The effectiveness of the proposed system is validated through an experiment on product catalog presentations

CFD Analysis of Oil Distribution in Oil-injected Screw Compressor

Oil-injected screw compressor has been used in various industries. After decades of continuous research efforts by research teams around the world, the computer tools for rotor profile design, thermodynamic analysis, CFD/CAE calculation, and moving grid generation have been well developed and widely employed in design works. With assistance from the computer tools in performance simulation, designers could clearly understand internal phenomena of a screw compressor, as a reference for performance optimization design, and systematically carry out research works. One important issue inside an oil-injected screw compressor is about oil distribution. Different oil-injected positions and quantities cause different oil distribution inside the compressor. Therefore, the effects of oil sealing and lubrication change. Designers must understand how oil distribution is to deal with oil issues. In this study, CFD analysis was done with dynamic grid technology. Basic performance of screw compressor was calculated and compared with experiment data. Besides, three CFD models with different oil-injected paths were designed and analyzed. The influence of varying oil-injected conditions on oil distribution near contact line, sealing lines, blow holes, and end sides of inlet and outlet are shown in this study. They are used to explain how volumetric efficiency is affected. Especially for oil distribution near contact line, it not only affects volumetric efficiency, but also acts on the lubrication as rotor meshing

Application of Computational Fluid Dynamics to the Lubrication Study of an Oil-injected Screw Compressor

Computational fluid dynamics and mesh generation tools have been well developed, and could be used to calculate the performance of an oil-injected screw compressor. Designers could now effectively obtain reliable results of efficiency, temperature, force and torque. Some physical phenomena inside a screw compressor are not easy to be observed through experiments, such as the oil distribution and the oil film thickness on the rotor surface. Under the ideal lubrication condition, the oil film of proper thickness should be maintained on the local surfaces which are going to contact with each other. This could be numerically explored by computational fluid dynamics. The first case in this study showed the effect of centrifugal force on a thin free surface flow on the rotor surface. Designers could graphically understand how the oil film flows on the rotor surface when rotors separately rotate without meshing with each other and doing the compression work. The second case in this study was the rotor lubrication. The clearance distribution between rotors in the actual contact area was designed by the minimum film thickness and was 1 μm. The pressure gradient on the rotor surface was used to see if the hydrodynamic pressure appeared. Designers could optimize the design of oil injection not only by considering efficiencies, but also by analyzing the pressure gradient and the oil film distribution on rotor surfaces