Vitamin D Levels Are Inversely Associated with Liver Fat Content and Risk of Non-Alcoholic Fatty Liver Disease in a Chinese Middle-Aged and Elderly Population: The Shanghai Changfeng Study - Fig 1

<p>The average LFC (%) in male (left) and female (right) subjects with different vitamin D status with a serum 25(OH)D <50nmol/L, = 50–75nmol/L and >75nmol/L. The liver fat content was significantly higher in male subjects with vitamin D deficiency and insufficiency, but not in female subjects.</p

Characteristics of the study participants according to vitamin D levels.

<p>Characteristics of the study participants according to vitamin D levels.</p

MOESM2 of Lipid profiling of the therapeutic effects of berberine in patients with nonalcoholic fatty liver disease

Additional file 2: Figure S1. The line graph of the glucose tolerance test (0–3 h). Data were mean ± SD, LSI: lifestyle intervention, BBR plus LSI: berberine treatment plus lifestyle intervention. *P < 0.05 when comparing before and after berberine plus lifestyle intervention treatment, #P < 0.05 when comparing before and after lifestyle intervention alone treatment

Multivariate regression analysis for the association between liver fat content (dependent variable) and 25(OH)D categories (independent variables) in different models in men.

<p>Multivariate regression analysis for the association between liver fat content (dependent variable) and 25(OH)D categories (independent variables) in different models in men.</p

Changes in the β and <i>P</i> values of age for AUCage after successively adjusting FPG, 2-h PG, eGFR, Hb and RBC count.

<p>Changes in the β and <i>P</i> values of age for AUCage after successively adjusting FPG, 2-h PG, eGFR, Hb and RBC count.</p

Characteristics of participants stratified by age.

<p>Characteristics of participants stratified by age.</p

Association between the liver fat content and prediabetes and diabetes.

a<p>: the risk for prediabetes;</p>b<p>: the risk for new-diabetes mellitus;</p>c<p>: adjusted for age, gender, alanine aminotransferase, aspartate aminotransferase, uric acid, body mass index, waist-to-hip ratio, systolic blood pressure, diastolic blood pressure, high-density lipoprotein cholesterol and triglycerides.</p

Relationship between the age and AUCage.

<p>The AUCage of HbA1c for diagnosing diabetes was negatively correlated with age (r = -0.557, <i>P</i> = 0.001). AUCage, area under the ROC curve in each one-year age group (aged 47–81 years, 35 groups in total).</p

Characteristics of the study participants stratified by the liver fat content.

<p>Data are means ± SE or percentages or percentages or median (25th to 75th percentiles).</p>a<p>P<0.05, ^bP<0.01 vs.quintile 1;</p>c<p>P<0.05, ^dP<0.01 vs. quintile 2;</p>e<p>P<0.05, ^fP<0.01 vs. quintile 3;</p>g<p>P<0.05, ^hP<0.01 vs. quintile 4;</p>i<p>: adjustment for age and gender;</p>j:<p>logarithmically transformed when compared.</p><p>Abbreviations: SBP: systolic blood pressure; DBP: diastolic blood pressure; WHR: waist-to-hip ratio; BMI: body mass index; FBG: fasting blood glucose; PPG: postload plasma glucose; TC: total cholesterol; HDL-c: high-density lipoprotein cholesterol; LDL-c: low-density lipoprotein cholesterol; TG: triglycerides; ALT: alanine aminotransferase; AST: aspartate aminotransferase; UA: uric acid; IFG: impaired fasting glucose; IGT: impaired glucose tolerance; DM: diabetes mellitus.</p

Changes in the β and <i>P</i> values of age for AUCage after adjusting FPG, 2-h PG, eGFR, Hb and RBC count separately.

<p>Changes in the β and <i>P</i> values of age for AUCage after adjusting FPG, 2-h PG, eGFR, Hb and RBC count separately.</p