1,480 research outputs found

    Dyson-Schwinger Equations with a Parameterized Metric

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    We construct and solve the Dyson-Schwinger equation (DSE) of quark propagator with a parameterized metric, which connects the Euclidean metric with the Minkowskian one. We show, in some models, the Minkowskian vacuum is different from the Euclidean vacuum. The usual analytic continuation of Green function does not make sense in these cases. While with the algorithm we proposed and the quark-gluon vertex ansatz which preserves the Ward-Takahashi identity, the vacuum keeps being unchanged in the evolution of the metric. In this case, analytic continuation becomes meaningful and can be fully carried out.Comment: 10 pages, 7 figures. To appear in Physical Review

    Method to Predict Crowding Effects by Postprocessing Molecular Dynamics Trajectories: Application to the Flap Dynamics of HIV-1 Protease.

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    The internal dynamics of proteins inside of cells may be affected by the crowded intracellular environments. Here, we test a novel approach to simulations of crowding, in which simulations in the absence of crowders are postprocessed to predict crowding effects, against the direct approach of simulations in the presence of crowders. The effects of crowding on the flap dynamics of HIV-1 protease predicted by the postprocessing approach are found to agree well with those calculated by the direct approach. The postprocessing approach presents distinct advantages over the direct approach in terms of accuracy and speed and is expected to have broad impact on atomistic simulations of macromolecular crowding

    Dissecting the High Rate Constant for the Binding of a Ribotoxin to the Ribosome

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    Phase diagram and critical endpoint for strongly-interacting quarks

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    We introduce a method based on the chiral susceptibility, which enables one to draw a phase diagram in the chemical-potential/temperature plane for strongly-interacting quarks whose interactions are described by any reasonable gap equation, even if the diagrammatic content of the quark-gluon vertex is unknown. We locate a critical endpoint (CEP) at (\mu^E,T^E) ~ (1.0,0.9)T_c, where T_c is the critical temperature for chiral symmetry restoration at \mu=0; and find that a domain of phase coexistence opens at the CEP whose area increases as a confinement length-scale grows.Comment: 4 pages, 3 figure

    Emerging Paradigms of Neural Network Pruning

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    Over-parameterization of neural networks benefits the optimization and generalization yet brings cost in practice. Pruning is adopted as a post-processing solution to this problem, which aims to remove unnecessary parameters in a neural network with little performance compromised. It has been broadly believed the resulted sparse neural network cannot be trained from scratch to comparable accuracy. However, several recent works (e.g., [Frankle and Carbin, 2019a]) challenge this belief by discovering random sparse networks which can be trained to match the performance with their dense counterpart. This new pruning paradigm later inspires more new methods of pruning at initialization. In spite of the encouraging progress, how to coordinate these new pruning fashions with the traditional pruning has not been explored yet. This survey seeks to bridge the gap by proposing a general pruning framework so that the emerging pruning paradigms can be accommodated well with the traditional one. With it, we systematically reflect the major differences and new insights brought by these new pruning fashions, with representative works discussed at length. Finally, we summarize the open questions as worthy future directions
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