Identifying the youngest HII regions in the Large Magellanic Cloud

Massive stars are known to play an important role in energizing the interstellar medium; however, their formation mechanism is still not well understood. In this study, we have identified compact HII regions around massive young stellar object so that follow-up observations can be made to study how massive stars are formed and how they affect the dynamics of the ambient cloud material in their early lifetime.Ope

Assessment of Runoff and Sediment Yields Using the AnnAGNPS Model in a Three-Gorge Watershed of China

Soil erosion has been recognized as one of the major threats to our environment and water quality worldwide, especially in China. To mitigate nonpoint source water quality problems caused by soil erosion, best management practices (BMPs) and/or conservation programs have been adopted. Watershed models, such as the Annualized Agricultural Non-Point Source Pollutant Loading model (AnnAGNPS), have been developed to aid in the evaluation of watershed response to watershed management practices. The model has been applied worldwide and proven to be a very effective tool in identifying the critical areas which had serious erosion, and in aiding in decision-making processes for adopting BMPs and/or conservation programs so that cost/benefit can be maximized and non-point source pollution control can be achieved in the most efficient way. The main goal of this study was to assess the characteristics of soil erosion, sediment and sediment delivery of a watershed so that effective conservation measures can be implemented. To achieve the overall objective of this study, all necessary data for the 4,184 km2 Daning River watershed in the Three-Gorge region of the Yangtze River of China were assembled. The model was calibrated using observed monthly runoff from 1998 to 1999 (Nash-Sutcliffe coefficient of efficiency of 0.94 and R2 of 0.94) and validated using the observed monthly runoff from 2003 to 2005 (Nash-Sutcliffe coefficient of efficiency of 0.93 and R2 of 0.93). Additionally, the model was validated using annual average sediment of 2000–2002 (relative error of −0.34) and 2003–2004 (relative error of 0.18) at Wuxi station. Post validation simulation showed that approximately 48% of the watershed was under the soil loss tolerance released by the Ministry of Water Resources of China (500 t·km−2·y−1). However, 8% of the watershed had soil erosion of exceeding 5,000 t·km−2·y−1. Sloping areas and low coverage areas are the main source of soil loss in the watershed

A Dinucleotide Deletion in CD24 Confers Protection against Autoimmune Diseases

It is generally believed that susceptibility to both organ-specific and systemic autoimmune diseases is under polygenic control. Although multiple genes have been implicated in each type of autoimmune disease, few are known to have a significant impact on both. Here, we investigated the significance of polymorphisms in the human gene CD24 and the susceptibility to multiple sclerosis (MS) and systemic lupus erythematosus (SLE). We used cases/control studies to determine the association between CD24 polymorphism and the risk of MS and SLE. In addition, we also considered transmission disequilibrium tests using family data from two cohorts consisting of a total of 150 pedigrees of MS families and 187 pedigrees of SLE families. Our analyses revealed that a dinucleotide deletion at position 1527∼1528 (P1527(del)) from the CD24 mRNA translation start site is associated with a significantly reduced risk (odds ratio = 0.54 with 95% confidence interval = 0.34–0.82) and delayed progression (p = 0.0188) of MS. Among the SLE cohort, we found a similar reduction of risk with the same polymorphism (odds ratio = 0.38, confidence interval = 0.22–0.62). More importantly, using 150 pedigrees of MS families from two independent cohorts and the TRANSMIT software, we found that the P1527(del) allele was preferentially transmitted to unaffected individuals (p = 0.002). Likewise, an analysis of 187 SLE families revealed the dinucleotide-deleted allele was preferentially transmitted to unaffected individuals (p = 0.002). The mRNA levels for the dinucleotide-deletion allele were 2.5-fold less than that of the wild-type allele. The dinucleotide deletion significantly reduced the stability of CD24 mRNA. Our results demonstrate that a destabilizing dinucleotide deletion in the 3′ UTR of CD24 mRNA conveys significant protection against both MS and SLE

Genotyping and biofilm formation of Mycoplasma hyopneumoniae and their association with virulence

Mycoplasma hyopneumoniae, the causative agent of swine respiratory disease, demonstrates differences in virulence. However, factors associated with this variation remain unknown. We herein evaluated the association between differences in virulence and genotypes as well as phenotype (i.e., biofilm formation ability). Strains 168 L, RM48, XLW-2, and J show low virulence and strains 232, 7448, 7422, 168, NJ, and LH show high virulence, as determined through animal challenge experiments, complemented with in vitro tracheal mucosa infection tests. These 10 strains with known virulence were then subjected to classification via multilocus sequence typing (MLST) with three housekeeping genes, P146-based genotyping, and multilocus variable-number tandem-repeat analysis (MLVA) of 13 loci. MLST and P146-based genotyping identified 168, 168 L, NJ, and RM48 as the same type and clustered them in a single branch. MLVA assigned a different sequence type to each strain. Simpson’s index of diversity indicates a higher discriminatory ability for MLVA. However, no statistically significant correlation was found between genotypes and virulence. Furthermore, we investigated the correlation between virulence and biofilm formation ability. The strains showing high virulence demonstrate strong biofilm formation ability, while attenuated strains show low biofilm formation ability. Pearson correlation analysis revealed a significant positive correlation between biofilm formation ability and virulence. To conclude, there was no association between virulence and our genotyping data, but virulence was found to be significantly associated with the biofilm formation ability of M. hyopneumoniae

Analysis of Urban Ecological Quality Spatial Patterns and Influencing Factors Based on Remote Sensing Ecological Indices and Multi-Scale Geographically Weighted Regression

With the acceleration of urbanization, problems such as urban ecological environment quality have become increasingly prominent. How to scientifically analyze and evaluate the spatial pattern of urban ecological environment changes and influential variables is a prerequisite for achieving green development and ecological priority new in urban planning. Our study was conducted on Pingtan Island, located in Fujian Province, China. First, we selected Landsat 8 OLI images in 2013, 2017, and 2021. Second, we extracted the remote sensing ecological index (RSEI) from these images and created RSEI maps to assess the spatial-temporal variations and spatial autocorrelation of the ecological environment condition in Pingtan Island. Third, the proportion of land-use types, road, and population density were selected as independent variable factors, RSEI as the dependent variable, least squares regression (OLS), geographically weighted regression (GWR), and multi-scale geographically weighted regression (MGWR) were used to establish global and local regression models. According to the regression coefficients of the model and its spatial distribution, the spatial heterogeneity between the ecological environment and the influencing factors was assessed. The results indicated that: (1) the mean value of the RSEI increased from 0.422 to 0.504 during 2013–2021, indicating that the overall ecological environment improved. (2) Based on the global Moran’s I value, the distribution of ecological environment quality was positively correlated. The local Moran’s I cluster map showed that the high-high cluster gradually extended to the northwest high-altitude region. Low-low clustering gradually extended to the more populous areas in the southeast. (3) The Radj2 of the MGWR model was 0.866, which was better than the results of the OLS model and GWR model, indicating that MGWR had obvious advantages in revealing the spatial heterogeneity between the ecological environment and the influencing factors. Importantly, the results indicate that population density, road density, and the proportion of cropland land and impervious surface in land-use types have varying degrees of negative effects on the urban ecological environment, with the impervious surface being more severe, followed by population density, while forest land in land-use types shows significant positive effects

Object-Based Distinction between Building Shadow and Water in High-Resolution Imagery Using Fuzzy-Rule Classification and Artificial Bee Colony Optimization

Due to the high similarity of the spectra of urban water and building shadows, high-resolution satellite imagery often confuses and wrongly classifies these features. To address this problem, we propose an object-based method for distinguishing building shadow from water using an artificial bee colony algorithm. In the method, four spectral ratio bands are first calculated as additional input parameters for improving the accuracy of segmentation results. During the segmentation, a series of statistical factors, such as spectrum, ratio, and sharp features, are calculated to make up for defects in the high-resolution imagery. Finally, we propose a fuzzy-rule-based classifier to generate extraction rules. The classifier is based on artificial bee colony optimization, which employs the geometric mean (G-mean) as fitness function. The proposed method was carried out on two test sites in Xiamen City. The experimental results based on GF-1 satellite date show that, compared with SVM method, the proposed method improved the overall accuracy of extraction by approximately 6% to 15% and the kappa coefficient values by approximately 0.1 to 0.2. The analysis of the extraction rules also proves that the red/NIR band and the length-width ratio band are significantly influenced by the distinction between building shadow and water

Simulating Urban Growth Using the SLEUTH Model in a Coastal Peri-Urban District in China

China’s southeast coastal areas have witnessed rapid growth in the last two decades, owing mostly to their economic and social attractions. In this paper, we chose Jimei, a coastal peri-urban district of Xiamen city on the southeast coast of China, as a study area to explore the district’s growth dynamics, to predict future sprawl during the next decade and to provide a basis for urban planning. The SLEUTH urban growth model was calibrated against historical data derived from a series of Landsat TM 5 satellite images taken between 1992 and 2007. A Lee-Sallee value of 0.48 was calculated for the district, which is a satisfactory result compared with related studies. Five coefficients of urban growth, diffusion, spread, breed, slope resistance and road gravity had values of 25, 68, 86, 24 and 23, respectively, in 2007. The growth coefficients (i.e., urban character) can capture urban growth characteristics in Jimei district. The urban DNA revealed that, over the study period, urban growth in the district was dominated both by urbanization through establishment of new urban centers, and by expansion outward from existing urban centers. In contrast to interior cities, in which expansions are dramatically shaped by actual road patterns, urban expansion in the district was likely constrained by the nearby coastline. Future urban growth patterns were predicted to 2020 assuming three different development scenarios. The first scenario simulated a continuation of historical urban growth without changing current conditions. The second scenario projected managed growth in which urban growth is limited by a layer with areas excluded from urbanization, which is the future development plan for Jimei district and Xiamen city. The third scenario depicted a growth with maximum protection in which growth was allowed to continue, similar to the second scenario, but with lower diffusion and spread coefficients applied to the growth pattern. The third scenario demonstrated that valuable land could be saved, which is the most desirable outcome for Jimei urban development. The study showed that SLEUTH can be an extremely useful tool for coastal city managers to explore the likely outcomes of their city development plans

Spatio–Temporal Variations in Impervious Surface Patterns during Urban Expansion in a Coastal City: Xiamen, China

Impervious surfaces (IS) coverage is a quantifiable environmental indicator for understanding urban sprawl and its potential impacts on sustainability of urban ecological environments. Numerous studies have previously demonstrated global and regional IS variation, but little attention has been paid to the different internal and external patterns of IS development as urbanization progresses. This study estimates IS coverage in a subtropical coastal area of Xiamen, southeastern China, from Landsat TM/OLI images obtained in 1994, 2000, 2004, 2010, and 2015, and quantifies its spatio–temporal variations using IS change trajectories and radar graphs. During the study period, IS gradually expanded along the shoreline in a pattern resembling the shape of the bay. The land surfaces are classified into four zones: IS1 and IS2, dominated by cultivated land and forest; IS3, complex land use/coverage; and IS4, built-up areas. The progression and transformations of these zones highlight the main trends in IS changes in the study area. The trajectories of the zones form a layered structure in which the urban centers of each district progressively gain IS4, and transformations into IS3 and IS2 extend successively beyond the centers. The orientation of IS expansion in each of the six districts of Xiamen is revealed by radar graphs. The areas containing intermediate and high percentages IS each expanded in generally consistent directions throughout the study period, except in Tong’an district, which showed a change in the direction of expansion of its area of intermediate and high IS

The Impacts of the Expansion of Urban Impervious Surfaces on Urban Heat Islands in a Coastal City in China

The effect of the expansion of urban impervious surfaces on surface urban heat islands (UHIs) has attracted research attention due to its relevance for studies of local climatic change and habitat comfort. In this study, using five satellite images of Xiamen city, Southeast China (four images from the Landsat 5 Thematic Mapper (TM) and one from the Landsat 8 Operational Land Imager/Thermal Infrared Sensor (OLI/TIRS)) acquired in summer between 1989 and 2016, together with spatial statistical methods, the changes in impervious surface area (ISA) were investigated, the spatiotemporal variation of the intensity of urban heat islands (UHIs) was explored, and the relationships between land surface temperature (LST) and the percentage of impervious surface area (ISA%), the normalized difference vegetation index (NDVI), and fractional vegetation coverage (Fv) were investigated. The results showed the following: (1) According to the biophysical composition index (BCI) combined with an ISA post-processing method, Xiamen has witnessed a substantial increase in ISA, showing a 6.1-fold increase from 1989 to 2016. The direction of ISA expansion was consistent throughout the study period in each of the five districts of Xiamen; (2) a bay-like UHI form is observed in the study area, which is remarkably distinct from the central-radial UHI form observed in previous studies of other cities; (3) the extent of UHIs in Xiamen greatly increased between 1989 and 2016, experiencing a 4.7-fold increase in UHI areas during this time. However, during the same period, the urban heat island ratio index (URI)—that is, the ratio of UHI area to ISA—decreased slightly. The UHI area decreased in some urban parts of Xiamen due to a significant increase in vegetation coverage, urban village redevelopment, and the construction of new parks; (4) sea ports and heavy industrial zones are the greatest contributor to surface UHI, followed by urban villages; and (5) LST is strongly positively correlated with ISA%. Each 10% increase in ISA was associated with an increase in summer LST of 0.41 to 0.91 K, which compares well with the results of related studies. This study presents valuable information for the development of regional urban planning strategies to mitigate the effects of UHIs during rapid urbanization