1 research outputs found
Concise synthesis of Didebromohamacanthin A and Demethylaplysinopsine: Addition of Ethylenediamine and Guanidine Derivatives to the Pyrrole-Amino Acid Diketopiperazines in Oxidative Conditions
Oxidative
nucleophilic addition of ethylenediamine and guanidine derivatives
to pyrrole-amino acid diketopiperazines was shown to provide substituted
5,6-dihydro-2(1<i>H</i>)-piperazinones, quinoxalinones,
and 2-aminoimidazolones. On the basis of this methodology, a concise
approach to natural products didebromohamacanthin A and demethylaplysinopsine
has been demonstrated