83 research outputs found
Myanmar Climate-Smart Agriculture Strategy
Myanmar has committed to apply CSA to contribute to regional food security and environmental protection during the 24th ASEAN Summit on May 10, 2014. The Myanmar CSA strategy encompasses the development of technical, policy and investment conditions to achieve a sustainable agricultural development for food security and nutrition through climate-resilient and sustainable agriculture. Myanmarâs CSA strategy aims to be socially, culturally and politically appropriate, environment-friendly and economically feasible to promote and attain sustainable agriculture, food security and nutrition, agricultural development and climate change adaptation and mitigation. Myanmarâs CSA strategy also aims to provide context and analysis for addressing agriculture in international climate negotiations to better inform climate negotiators and other stakeholders by identifying options and unpacking issues of interest
English Intermediate-Task Training Improves Zero-Shot Cross-Lingual Transfer Too
Intermediate-task training---fine-tuning a pretrained model on an
intermediate task before fine-tuning again on the target task---often improves
model performance substantially on language understanding tasks in monolingual
English settings. We investigate whether English intermediate-task training is
still helpful on non-English target tasks. Using nine intermediate
language-understanding tasks, we evaluate intermediate-task transfer in a
zero-shot cross-lingual setting on the XTREME benchmark. We see large
improvements from intermediate training on the BUCC and Tatoeba sentence
retrieval tasks and moderate improvements on question-answering target tasks.
MNLI, SQuAD and HellaSwag achieve the best overall results as intermediate
tasks, while multi-task intermediate offers small additional improvements.
Using our best intermediate-task models for each target task, we obtain a 5.4
point improvement over XLM-R Large on the XTREME benchmark, setting the state
of the art as of June 2020. We also investigate continuing multilingual MLM
during intermediate-task training and using machine-translated
intermediate-task data, but neither consistently outperforms simply performing
English intermediate-task training
Second Primary Malignancies after Autologous Hematopoietic Cell Transplantation for Multiple Myeloma
AbstractRecent studies demonstrate an increased risk of second primary malignancies (SPMs) in patients with multiple myeloma (MM) receiving maintenance lenalidomide after autologous stem cell transplantation (ASCT). We explored the possibility of other risk factors driving post-ASCT SPMs in patients with MM through analysis of our large transplantation database in conjunction with our Long-Term Follow-Up Program. We conducted a retrospective cohort study of 841 consecutive patients with MM who underwent ASCT at City of Hope between 1989 and 2009, as well as a nested case-control analysis evaluating the role of all therapeutic exposures before, during, and after ASCT. Median duration of follow-up for the entire cohort was 3.4 years (range, 0.3-19.9 years). Sixty cases with a total of 70 SPMs were identified. The overall cumulative incidence of SPMs was 7.4% at 5 years and 15.9% at 10 years when nonmelanoma skin cancers (NMSCs) were included and 5.3% at 5 years and 11.2% at 10 years when NMSCs were excluded. Multivariate analysis of the entire cohort revealed associations of both older age (â„55 years; relative risk, 2.3; P < .004) and race (non-Hispanic white; relative risk, 2.4; PÂ = .01) with an increased risk of SPM. Furthermore, thalidomide exposure demonstrated a trend toward increased risk (odds ratio, 3.5; PÂ = .15); however, an insufficient number of patients were treated with lenalidomide to allow us to accurately assess the risk of this agent. Exclusion of NMSCs retained the association with these variables but was accompanied by loss of statistical significance. This large single-institution analysis identified associations between race and older age and increased risk of developing SPM. The trend toward increased risk with thalidomide exposure suggests a class effect from immunomodulatory drugs that might not be restricted to lenalidomide
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